hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03414
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NEK2 | Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) | UniProt NCBI |
| TRIP11 | Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) | UniProt NCBI |
| BFSP1 | Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H) | UniProt NCBI |
| BFSP2 | Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L) | UniProt NCBI |
| CENPE | Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-7) (Kinesin-related protein CENPE) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000478 | 0.0345715487774 | 1.0 | NEK2 TRIP11 BFSP1 CENPE BFSP2 | Abnormality of the eye |
| CORUM:1932 | 0.0499494897235 | 0.2 | NEK2 | NEK2-NEK11 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BFSP1 | BFSP2 | 0.92 | 0.843 | bioplex (BFSP2) bioplex_WMM |
| BFSP2 | TRIP11 | 0.383 | 0.551 | bioplex (BFSP2) bioplex_WMM |
| BFSP2 | NEK2 | 0.146 | 0.408 | bioplex (BFSP2) bioplex_WMM |
| BFSP2 | CENPE | 0.108 | 0.373 | bioplex (BFSP2) bioplex_WMM boldt_WMM |
| BFSP1 | CENPE | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CENPE | NEK2 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| TRIP11 | CENPE | 0.008 | 0.061 | bioplex_WMM WMM_only boldt_WMM |
| BFSP1 | NEK2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| BFSP1 | TRIP11 | 0.008 | 0.044 | bioplex_WMM youn_WMM WMM_only |
| TRIP11 | NEK2 | 0.008 | 0.04 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03414 has an average edge precision of 0.251 which is ranked 5359 out of all 6965 complexes.
Related Complexes