hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03435
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRMT1L | TRMT1-like protein (EC 2.1.1.-) | UniProt NCBI |
| RRP7A | Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) | UniProt NCBI |
| NTPCR | Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase) | UniProt NCBI |
| RPS27L | 40S ribosomal protein S27-like (Small ribosomal subunit protein eS27-like) | UniProt NCBI |
| RPS20 | 40S ribosomal protein S20 (Small ribosomal subunit protein uS10) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 0.00259573944873 | 0.6 | RPS20 RPS27L RRP7A | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00304975168622 | 0.6 | RPS20 RPS27L RRP7A | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00355347569673 | 0.6 | RPS20 RPS27L RRP7A | rRNA processing |
| REAC:R-HSA-72695 | 0.017778070678 | 0.4 | RPS27L RPS20 | Formation of the ternary complex, and subsequently, the 43S complex |
| REAC:R-HSA-72702 | 0.0229182830201 | 0.4 | RPS27L RPS20 | Ribosomal scanning and start codon recognition |
| REAC:R-HSA-72649 | 0.0229182830201 | 0.4 | RPS27L RPS20 | Translation initiation complex formation |
| REAC:R-HSA-72662 | 0.0237053784759 | 0.4 | RPS27L RPS20 | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| KEGG:03010 | 0.0353865382697 | 0.4 | RPS27L RPS20 | Ribosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPS20 | RPS27L | 0.394 | 0.555 | hein_WMM bioplex (RPS27L) bioplex_WMM gupta_WMM fraction treiber_WMM |
| RRP7A | RPS20 | 0.274 | 0.486 | bioplex (RRP7A) bioplex_WMM Malo gupta_WMM fraction treiber_WMM |
| RPS20 | TRMT1L | 0.131 | 0.402 | hein_WMM bioplex (TRMT1L) bioplex_WMM gupta_WMM fraction |
| TRMT1L | NTPCR | 0.089 | 0.356 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RPS20 | NTPCR | 0.035 | 0.265 | bioplex_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RRP7A | TRMT1L | 0.009 | 0.107 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RPS27L | TRMT1L | 0.007 | 0.006 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RRP7A | NTPCR | 0.007 | 0.006 | youn_WMM WMM_only |
| RRP7A | RPS27L | 0.007 | 0.002 | youn_WMM WMM_only |
| RPS27L | NTPCR | 0.005 | 0.009 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_03435 has an average edge precision of 0.219 which is ranked 5863 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRMT1L | HuMAP2_02367 HuMAP2_03435 |
| RRP7A | HuMAP2_02186 HuMAP2_02370 HuMAP2_03435 HuMAP2_04524 HuMAP2_06514 |
| NTPCR | HuMAP2_02367 HuMAP2_03435 |
| RPS27L | HuMAP2_02207 HuMAP2_03435 HuMAP2_03749 |
| RPS20 | HuMAP2_02207 HuMAP2_03435 HuMAP2_03749 HuMAP2_05622 |