hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03437

Confidence: Extremely High

Genename	Protein Name	Links
ELMO1	Engulfment and cell motility protein 1 (Protein ced-12 homolog)	UniProt NCBI
DOCK1	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:5337	1.67592346237e-06	1.0	DOCK1 ELMO1	ELMO1-DOCK1 complex
CORUM:5342	5.02777038712e-06	1.0	DOCK1 ELMO1	ELMO1-DOCK1-RAC1 complex
CORUM:5343	5.02777038712e-06	1.0	DOCK1 ELMO1	ELMO1-DOCK1-CRKII complex
REAC:R-HSA-8849471	0.000130722030065	1.0	DOCK1 ELMO1	PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
KEGG:05131	0.000294129448977	1.0	DOCK1 ELMO1	Shigellosis
KEGG:05100	0.000383418745988	1.0	DOCK1 ELMO1	Bacterial invasion of epithelial cells
REAC:R-HSA-9006927	0.00173458078356	1.0	DOCK1 ELMO1	Signaling by Non-Receptor Tyrosine Kinases
REAC:R-HSA-8848021	0.00173458078356	1.0	DOCK1 ELMO1	Signaling by PTK6
REAC:R-HSA-2029482	0.00286750504412	1.0	DOCK1 ELMO1	Regulation of actin dynamics for phagocytic cup formation
REAC:R-HSA-2029480	0.0052959181411	1.0	DOCK1 ELMO1	Fcgamma receptor (FCGR) dependent phagocytosis
REAC:R-HSA-4420097	0.00686290657842	1.0	DOCK1 ELMO1	VEGFA-VEGFR2 Pathway
REAC:R-HSA-194138	0.00812990471598	1.0	DOCK1 ELMO1	Signaling by VEGF
GO:0032045	0.020287053512	1.0	DOCK1 ELMO1	guanyl-nucleotide exchange factor complex
CORUM:5341	0.0499173803268	0.5	ELMO1	ELMO1-DOCK2 complex

Protein 1	Protein 2	Score	Precision	Evidence
ELMO1	DOCK1	1.0	0.949	bioplex (ELMO1) bioplex_WMM

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ComplexPrecisionDistribution

Complex HuMAP2_03437 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.

Related Complexes

Genename	Complexes
ELMO1	HuMAP2_00971 HuMAP2_01146 HuMAP2_02044 HuMAP2_03199 HuMAP2_03437 HuMAP2_03968 HuMAP2_04556 HuMAP2_05175 HuMAP2_05349
DOCK1	HuMAP2_01146 HuMAP2_03199 HuMAP2_03437 HuMAP2_03968 HuMAP2_04378 HuMAP2_04556 HuMAP2_05175 HuMAP2_05349 HuMAP2_05575