hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03444
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SUPT16H | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) | UniProt NCBI |
| SSRP1 | FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:936 | 1.67592346237e-06 | 1.0 | SUPT16H SSRP1 | FACT complex |
| CORUM:934 | 5.02777038712e-06 | 1.0 | SUPT16H SSRP1 | FACT-NEK9 complex |
| CORUM:938 | 1.67592346237e-05 | 1.0 | SUPT16H SSRP1 | FACT complex, UV-activated |
| CORUM:1223 | 9.21757904306e-05 | 1.0 | SUPT16H SSRP1 | H2AX complex, isolated from cells without IR exposure |
| CORUM:7388 | 0.000152509035076 | 1.0 | SUPT16H SSRP1 | CENP-A nucleosomal complex |
| REAC:R-HSA-167238 | 0.000831258037338 | 1.0 | SUPT16H SSRP1 | Pausing and recovery of Tat-mediated HIV elongation |
| REAC:R-HSA-167243 | 0.000831258037338 | 1.0 | SUPT16H SSRP1 | Tat-mediated HIV elongation arrest and recovery |
| REAC:R-HSA-167287 | 0.000940193062392 | 1.0 | SUPT16H SSRP1 | HIV elongation arrest and recovery |
| REAC:R-HSA-167290 | 0.000940193062392 | 1.0 | SUPT16H SSRP1 | Pausing and recovery of HIV elongation |
| CORUM:929 | 0.00111616502594 | 1.0 | SUPT16H SSRP1 | CEN complex |
| REAC:R-HSA-167200 | 0.00158542359541 | 1.0 | SUPT16H SSRP1 | Formation of HIV-1 elongation complex containing HIV-1 Tat |
| REAC:R-HSA-167169 | 0.00158542359541 | 1.0 | SUPT16H SSRP1 | HIV Transcription Elongation |
| REAC:R-HSA-167246 | 0.00158542359541 | 1.0 | SUPT16H SSRP1 | Tat-mediated elongation of the HIV-1 transcript |
| REAC:R-HSA-167152 | 0.00173458078356 | 1.0 | SUPT16H SSRP1 | Formation of HIV elongation complex in the absence of HIV Tat |
| GO:0035101 | 0.00270494046827 | 1.0 | SUPT16H SSRP1 | FACT complex |
| REAC:R-HSA-112382 | 0.00286750504412 | 1.0 | SUPT16H SSRP1 | Formation of RNA Pol II elongation complex |
| REAC:R-HSA-75955 | 0.00286750504412 | 1.0 | SUPT16H SSRP1 | RNA Polymerase II Transcription Elongation |
| REAC:R-HSA-6796648 | 0.00316917126735 | 1.0 | SUPT16H SSRP1 | TP53 Regulates Transcription of DNA Repair Genes |
| REAC:R-HSA-167172 | 0.004164669804 | 1.0 | SUPT16H SSRP1 | Transcription of the HIV genome |
| REAC:R-HSA-674695 | 0.00556574181855 | 1.0 | SUPT16H SSRP1 | RNA Polymerase II Pre-transcription Events |
| REAC:R-HSA-6804756 | 0.00686290657842 | 1.0 | SUPT16H SSRP1 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-162599 | 0.0147112561527 | 1.0 | SUPT16H SSRP1 | Late Phase of HIV Life Cycle |
| REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | SUPT16H SSRP1 | HIV Life Cycle |
| REAC:R-HSA-5633007 | 0.0205233587202 | 1.0 | SUPT16H SSRP1 | Regulation of TP53 Activity |
| REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | SUPT16H SSRP1 | HIV Infection |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SUPT16H | SSRP1 | 1.0 | 0.949 | hein_WMM bioplex (SSRP1) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_03444 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SUPT16H | HuMAP2_00227 HuMAP2_03444 |
| SSRP1 | HuMAP2_00586 HuMAP2_03444 |