hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03462
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDGFC | Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)] | UniProt NCBI |
| HCFC1 | Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] | UniProt NCBI |
| CREB3 | Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)] | UniProt NCBI |
| THAP11 | THAP domain-containing protein 11 | UniProt NCBI |
| DPY30 | Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L) | UniProt NCBI |
| THAP2 | THAP domain-containing protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7224 | 8.39001385941e-06 | 0.333333333333 | THAP11 HCFC1 | HCF1-THAP11 complex |
| CORUM:7260 | 8.39001385941e-06 | 0.333333333333 | THAP11 HCFC1 | HCFC1-THAP11 subcomplex |
| CORUM:7259 | 2.51655344529e-05 | 0.333333333333 | THAP11 HCFC1 | HCFC1-THAP11-ZNF143 complex |
| CORUM:6462 | 0.000234668084372 | 0.333333333333 | DPY30 HCFC1 | MLL1 complex |
| CORUM:6460 | 0.000377010054596 | 0.333333333333 | DPY30 HCFC1 | MLL2 complex |
| CORUM:6469 | 0.000377010054596 | 0.333333333333 | DPY30 HCFC1 | Set1A complex |
| CORUM:6470 | 0.000552750021156 | 0.333333333333 | DPY30 HCFC1 | Set1B complex |
| KEGG:05215 | 0.0246844798555 | 0.333333333333 | PDGFC CREB3 | Prostate cancer |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HCFC1 | CREB3 | 0.471 | 0.606 | bioplex (CREB3) bioplex_WMM |
| CREB3 | PDGFC | 0.277 | 0.485 | bioplex (CREB3) bioplex_WMM |
| HCFC1 | THAP11 | 0.172 | 0.432 | bioplex (THAP11) bioplex_WMM gupta_WMM |
| HCFC1 | THAP2 | 0.035 | 0.265 | bioplex (THAP2) bioplex_WMM |
| HCFC1 | DPY30 | 0.026 | 0.219 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| HCFC1 | PDGFC | 0.008 | 0.047 | bioplex_WMM WMM_only |
| THAP11 | DPY30 | 0.007 | 0.004 | gupta_WMM WMM_only |
Images
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Complex HuMAP2_03462 has an average edge precision of 0.294 which is ranked 4687 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDGFC | HuMAP2_03133 HuMAP2_03462 HuMAP2_03732 HuMAP2_06679 |
| HCFC1 | HuMAP2_01857 HuMAP2_03385 HuMAP2_03462 |
| CREB3 | HuMAP2_03133 HuMAP2_03462 HuMAP2_03732 HuMAP2_06679 |
| THAP11 | HuMAP2_01857 HuMAP2_03385 HuMAP2_03462 HuMAP2_04625 |
| DPY30 | HuMAP2_03462 HuMAP2_03800 |
| THAP2 | HuMAP2_01857 HuMAP2_03462 |