hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03472
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBM8A | RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A) | UniProt NCBI |
| PYM1 | Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) | UniProt NCBI |
| MAGOH | Protein mago nashi homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:755 | 2.25356268047e-09 | 1.0 | PYM1 MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM) |
| KEGG:03015 | 3.30002227102e-06 | 1.0 | PYM1 MAGOH RBM8A | mRNA surveillance pathway |
| CORUM:773 | 3.35600554376e-06 | 0.666666666667 | MAGOH RBM8A | Y14-Magoh complex |
| CORUM:763 | 3.35600554376e-06 | 0.666666666667 | MAGOH RBM8A | Y14-Magoh complex |
| CORUM:1293 | 1.00675659188e-05 | 0.666666666667 | MAGOH RBM8A | IPO13-RBM8A-MAGOH complex |
| KEGG:03013 | 1.76006400333e-05 | 1.0 | PYM1 MAGOH RBM8A | RNA transport |
| CORUM:769 | 2.01342304124e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:754 | 2.01342304124e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14) |
| CORUM:744 | 2.01342304124e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:740 | 2.01342304124e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:6742 | 5.03310689057e-05 | 0.666666666667 | MAGOH RBM8A | SMG1-UPF2-Y14-MAGOH-UPF3B-EIF4A3 complex |
| CORUM:785 | 7.04603414803e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex |
| GO:0035145 | 8.80032001664e-05 | 1.0 | PYM1 MAGOH RBM8A | exon-exon junction complex |
| KEGG:03040 | 0.00373360278335 | 0.666666666667 | MAGOH RBM8A | Spliceosome |
| REAC:R-HSA-72187 | 0.00955880978777 | 0.666666666667 | MAGOH RBM8A | mRNA 3'-end processing |
| CORUM:1181 | 0.010043796241 | 0.666666666667 | MAGOH RBM8A | C complex spliceosome |
| REAC:R-HSA-73856 | 0.0130404028432 | 0.666666666667 | MAGOH RBM8A | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 0.015207050821 | 0.666666666667 | MAGOH RBM8A | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.0195249561753 | 0.666666666667 | MAGOH RBM8A | Transport of Mature Transcript to Cytoplasm |
| GO:0000184 | 0.0212638981157 | 1.0 | PYM1 MAGOH RBM8A | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| CORUM:351 | 0.0324522040239 | 0.666666666667 | MAGOH RBM8A | Spliceosome |
| REAC:R-HSA-927802 | 0.0421579398286 | 0.666666666667 | MAGOH RBM8A | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-975957 | 0.0421579398286 | 0.666666666667 | MAGOH RBM8A | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| HPA:014010_13 | 0.043989983869 | 0.666666666667 | RBM8A PYM1 | endometrium 2; cells in endometrial stroma[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAGOH | RBM8A | 1.0 | 0.949 | hein_WMM bioplex (MAGOH) bioplex_WMM youn_WMM hein (MAGOH,RBM8A) gupta_WMM treiber_WMM |
| MAGOH | PYM1 | 1.0 | 0.949 | hein_WMM bioplex (MAGOH,PYM1) bioplex_WMM youn_WMM hein (MAGOH) |
| RBM8A | PYM1 | 0.384 | 0.55 | hein_WMM bioplex (PYM1) bioplex_WMM youn_WMM hein (RBM8A) gupta_WMM |
Images
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Complex HuMAP2_03472 has an average edge precision of 0.816 which is ranked 895 out of all 6965 complexes.
Related Complexes