hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03515

Confidence: Medium

Genename	Protein Name	Links
MUL1	Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 2.3.2.27) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (MAPL) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218) (RING-type E3 ubiquitin transferase NFKB 1)	UniProt NCBI
PEX19	Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein)	UniProt NCBI
FAM174A	Membrane protein FAM174A (Hepatitis C virus NS5A-transactivated protein 6) (HCV NS5A-transactivated protein 6) (Transmembrane protein 157)	UniProt NCBI
EXOG	Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1)	UniProt NCBI
EXD2	Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2)	UniProt NCBI
SELENOT	Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9)	UniProt NCBI
SELENON	Selenoprotein N (SelN)	UniProt NCBI
MARC2	Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2)	UniProt NCBI
PXMP2	Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein)	UniProt NCBI
NAT14	N-acetyltransferase 14 (EC 2.3.1.-) (K562 cell-derived leucine-zipper-like protein 1)	UniProt NCBI
GLCE	D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase)	UniProt NCBI
RDH12	Retinol dehydrogenase 12 (EC 1.1.1.300) (All-trans and 9-cis retinol dehydrogenase) (Short chain dehydrogenase/reductase family 7C member 2)	UniProt NCBI
TMEM168	Transmembrane protein 168	UniProt NCBI
MGAT2	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II)	UniProt NCBI
MOSPD2	Motile sperm domain-containing protein 2	UniProt NCBI
LETMD1	LETM1 domain-containing protein 1 (Cervical cancer 1 proto-oncogene protein p40) (Cervical cancer proto-oncogene 2 protein) (HCCR-1) (HCRR-2)	UniProt NCBI
B3GALT6	Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)	UniProt NCBI
PEX16	Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16)	UniProt NCBI
HIGD2A	HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b)	UniProt NCBI
QPCTL	Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9603798	0.000465947116487	0.15	PEX19 PXMP2 PEX16	Class I peroxisomal membrane protein import
KEGG:04146	0.00734412325133	0.15	PEX19 PXMP2 PEX16	Peroxisome
KEGG:00534	0.0217545674106	0.1	B3GALT6 GLCE	Glycosaminoglycan biosynthesis - heparan sulfate / heparin
HP:0010656	0.0261172866386	0.15	PEX19 PEX16 B3GALT6	Abnormal epiphyseal ossification

Edges

Protein 1	Protein 2	Score	Precision	Evidence
PEX19	NAT14	0.609	0.674	bioplex (PEX19) bioplex_WMM boldt boldt_WMM
PEX19	MOSPD2	0.4	0.56	bioplex (PEX19) bioplex_WMM
PEX19	MUL1	0.396	0.556	bioplex (PEX19) bioplex_WMM
PEX19	MGAT2	0.212	0.461	bioplex (PEX19) bioplex_WMM
PEX19	PXMP2	0.174	0.432	bioplex (PEX19) bioplex_WMM
EXD2	PEX19	0.16	0.418	bioplex (PEX19) bioplex_WMM
MARC2	PEX19	0.128	0.399	bioplex (PEX19) bioplex_WMM
PEX19	RDH12	0.105	0.369	bioplex (PEX19,RDH12) bioplex_WMM
FAM174A	PEX19	0.071	0.351	bioplex (FAM174A,PEX19) bioplex_WMM
PEX19	SELENON	0.067	0.35	bioplex (PEX19) bioplex_WMM
PEX19	EXOG	0.059	0.333	bioplex (PEX19) bioplex_WMM
FAM174A	TMEM168	0.047	0.293	bioplex (FAM174A) bioplex_WMM
PEX19	B3GALT6	0.041	0.269	bioplex (PEX19) bioplex_WMM
SELENOT	PEX19	0.027	0.227	bioplex (PEX19) bioplex_WMM
PEX19	GLCE	0.026	0.22	bioplex (PEX19) bioplex_WMM
PEX19	QPCTL	0.025	0.217	bioplex (PEX19) bioplex_WMM
PEX19	PEX16	0.025	0.213	bioplex (PEX19) bioplex_WMM
PEX19	LETMD1	0.024	0.214	bioplex (PEX19) bioplex_WMM
PEX19	HIGD2A	0.02	0.184	bioplex (PEX19) bioplex_WMM
LETMD1	PEX16	0.009	0.092	bioplex_WMM WMM_only
GLCE	MUL1	0.009	0.098	bioplex_WMM WMM_only
NAT14	LETMD1	0.008	0.096	bioplex_WMM WMM_only
SELENOT	PEX16	0.008	0.096	bioplex_WMM WMM_only
MARC2	HIGD2A	0.008	0.089	bioplex_WMM WMM_only
FAM174A	HIGD2A	0.008	0.089	bioplex_WMM WMM_only
RDH12	HIGD2A	0.008	0.089	bioplex_WMM WMM_only
FAM174A	MARC2	0.008	0.091	bioplex_WMM WMM_only
MARC2	RDH12	0.008	0.09	bioplex_WMM WMM_only
FAM174A	RDH12	0.008	0.081	bioplex_WMM WMM_only
GLCE	HIGD2A	0.008	0.083	bioplex_WMM WMM_only
MARC2	GLCE	0.008	0.084	bioplex_WMM WMM_only
FAM174A	GLCE	0.008	0.082	bioplex_WMM WMM_only
PEX16	HIGD2A	0.008	0.083	bioplex_WMM WMM_only
GLCE	RDH12	0.008	0.082	bioplex_WMM WMM_only
MARC2	PEX16	0.008	0.08	bioplex_WMM WMM_only
PEX16	MUL1	0.008	0.081	bioplex_WMM WMM_only
FAM174A	PEX16	0.008	0.067	bioplex_WMM WMM_only
LETMD1	MUL1	0.008	0.066	bioplex_WMM WMM_only
PEX16	RDH12	0.008	0.067	bioplex_WMM WMM_only
SELENOT	LETMD1	0.008	0.07	bioplex_WMM WMM_only
NAT14	RDH12	0.008	0.062	bioplex_WMM WMM_only
GLCE	PEX16	0.008	0.06	bioplex_WMM WMM_only
EXOG	HIGD2A	0.008	0.058	bioplex_WMM WMM_only
MARC2	EXOG	0.008	0.055	bioplex_WMM WMM_only
FAM174A	EXOG	0.008	0.043	bioplex_WMM WMM_only
EXOG	RDH12	0.008	0.044	bioplex_WMM WMM_only
EXD2	HIGD2A	0.008	0.035	bioplex_WMM WMM_only
LETMD1	HIGD2A	0.008	0.031	bioplex_WMM WMM_only
MARC2	LETMD1	0.008	0.036	bioplex_WMM WMM_only
SELENOT	HIGD2A	0.008	0.033	bioplex_WMM WMM_only
EXOG	GLCE	0.008	0.028	bioplex_WMM WMM_only
SELENOT	MARC2	0.008	0.03	bioplex_WMM WMM_only
FAM174A	LETMD1	0.008	0.031	bioplex_WMM WMM_only
LETMD1	RDH12	0.008	0.022	bioplex_WMM WMM_only
SELENOT	FAM174A	0.008	0.025	bioplex_WMM WMM_only
EXOG	MUL1	0.008	0.025	bioplex_WMM WMM_only
SELENOT	RDH12	0.008	0.026	bioplex_WMM WMM_only
EXOG	PEX16	0.008	0.028	bioplex_WMM WMM_only
MUL1	HIGD2A	0.008	0.028	bioplex_WMM WMM_only
MARC2	MUL1	0.008	0.016	bioplex_WMM WMM_only
PXMP2	HIGD2A	0.008	0.013	bioplex_WMM WMM_only boldt_WMM
LETMD1	GLCE	0.008	0.025	bioplex_WMM WMM_only
MOSPD2	HIGD2A	0.008	0.025	bioplex_WMM WMM_only
MARC2	MOSPD2	0.008	0.016	bioplex_WMM WMM_only
HIGD2A	QPCTL	0.008	0.014	bioplex_WMM WMM_only boldt_WMM
FAM174A	MUL1	0.008	0.01	bioplex_WMM WMM_only
SELENOT	GLCE	0.008	0.012	bioplex_WMM WMM_only
MUL1	RDH12	0.008	0.013	bioplex_WMM WMM_only
GLCE	QPCTL	0.008	0.01	bioplex_WMM WMM_only
SELENOT	EXOG	0.008	0.014	bioplex_WMM WMM_only
FAM174A	MOSPD2	0.008	0.012	bioplex_WMM WMM_only
MOSPD2	RDH12	0.007	0.013	bioplex_WMM WMM_only
EXD2	PEX16	0.007	0.009	bioplex_WMM WMM_only
MGAT2	HIGD2A	0.007	0.009	bioplex_WMM WMM_only
MOSPD2	GLCE	0.007	0.003	bioplex_WMM WMM_only
MARC2	QPCTL	0.007	0.012	bioplex_WMM WMM_only
MARC2	PXMP2	0.007	0.007	bioplex_WMM WMM_only
MARC2	EXD2	0.007	0.008	bioplex_WMM WMM_only
MOSPD2	PEX16	0.007	0.011	bioplex_WMM WMM_only
FAM174A	PXMP2	0.007	0.008	bioplex_WMM WMM_only
PXMP2	RDH12	0.007	0.014	bioplex_WMM WMM_only
RDH12	QPCTL	0.007	0.012	bioplex_WMM WMM_only
EXOG	LETMD1	0.007	0.011	bioplex_WMM WMM_only
FAM174A	EXD2	0.007	0.009	bioplex_WMM WMM_only
EXD2	RDH12	0.007	0.006	bioplex_WMM WMM_only
B3GALT6	GLCE	0.007	0.006	bioplex_WMM WMM_only
PXMP2	PEX16	0.007	0.005	bioplex_WMM WMM_only
MARC2	NAT14	0.007	0.003	bioplex_WMM WMM_only
NAT14	HIGD2A	0.007	0.003	bioplex_WMM WMM_only
PXMP2	GLCE	0.007	0.005	bioplex_WMM WMM_only
MARC2	MGAT2	0.007	0.003	bioplex_WMM WMM_only
EXD2	GLCE	0.007	0.005	bioplex_WMM WMM_only
FAM174A	NAT14	0.007	0.004	bioplex_WMM WMM_only
FAM174A	SELENON	0.007	0.004	bioplex_WMM WMM_only
FAM174A	MGAT2	0.007	0.003	bioplex_WMM WMM_only
MGAT2	RDH12	0.007	0.001	bioplex_WMM WMM_only
NAT14	PEX16	0.007	0.004	bioplex_WMM WMM_only
TMEM168	PEX19	0.007	0.004	bioplex_WMM WMM_only
MOSPD2	EXOG	0.007	0.003	bioplex_WMM WMM_only
SELENOT	QPCTL	0.007	0.002	bioplex_WMM WMM_only boldt_WMM
PEX16	QPCTL	0.007	0.001	bioplex_WMM WMM_only
SELENOT	MUL1	0.007	0.003	bioplex_WMM WMM_only
SELENON	HIGD2A	0.007	0.004	bioplex_WMM WMM_only
MARC2	SELENON	0.007	0.002	bioplex_WMM WMM_only
NAT14	GLCE	0.007	0.002	bioplex_WMM WMM_only
LETMD1	QPCTL	0.007	0.001	bioplex_WMM WMM_only
EXD2	LETMD1	0.007	0.002	bioplex_WMM WMM_only
MGAT2	GLCE	0.007	0.002	bioplex_WMM WMM_only
B3GALT6	HIGD2A	0.007	0.003	bioplex_WMM WMM_only
MARC2	B3GALT6	0.007	0.002	bioplex_WMM WMM_only
SELENON	RDH12	0.007	0.003	bioplex_WMM WMM_only
MOSPD2	LETMD1	0.007	0.003	bioplex_WMM WMM_only
SELENOT	MOSPD2	0.007	0.001	bioplex_WMM WMM_only
PXMP2	EXOG	0.007	0.002	bioplex_WMM WMM_only
TMEM168	SELENON	0.007	0.0	bioplex_WMM WMM_only
B3GALT6	RDH12	0.007	0.002	bioplex_WMM WMM_only
B3GALT6	PEX16	0.007	0.002	bioplex_WMM WMM_only
TMEM168	B3GALT6	0.007	0.005	bioplex_WMM WMM_only
SELENON	GLCE	0.007	0.005	bioplex_WMM WMM_only
EXD2	EXOG	0.007	0.002	bioplex_WMM WMM_only
MOSPD2	MUL1	0.007	0.006	bioplex_WMM WMM_only
MGAT2	PEX16	0.007	0.003	bioplex_WMM WMM_only
SELENON	PEX16	0.007	0.006	bioplex_WMM WMM_only
PXMP2	LETMD1	0.007	0.003	bioplex_WMM WMM_only
MGAT2	EXOG	0.007	0.006	bioplex_WMM WMM_only
NAT14	EXOG	0.007	0.004	bioplex_WMM WMM_only
SELENOT	PXMP2	0.007	0.003	bioplex_WMM WMM_only
EXOG	QPCTL	0.007	0.001	bioplex_WMM boldt boldt_WMM
SELENOT	EXD2	0.007	0.002	bioplex_WMM WMM_only
PXMP2	MUL1	0.007	0.002	bioplex_WMM WMM_only
MOSPD2	QPCTL	0.007	0.006	bioplex_WMM WMM_only
NAT14	MUL1	0.007	0.0	bioplex_WMM WMM_only boldt_WMM
MGAT2	LETMD1	0.007	0.003	bioplex_WMM WMM_only
EXD2	MOSPD2	0.007	0.005	bioplex_WMM WMM_only
SELENOT	NAT14	0.007	0.002	bioplex_WMM WMM_only
PXMP2	MOSPD2	0.007	0.005	bioplex_WMM WMM_only
LETMD1	B3GALT6	0.007	0.004	bioplex_WMM WMM_only
SELENON	LETMD1	0.006	0.004	bioplex_WMM WMM_only
MGAT2	MOSPD2	0.006	0.006	bioplex_WMM WMM_only
EXD2	MUL1	0.006	0.006	bioplex_WMM WMM_only
MGAT2	MUL1	0.006	0.003	bioplex_WMM WMM_only
EXOG	SELENON	0.006	0.005	bioplex_WMM WMM_only
EXOG	B3GALT6	0.006	0.007	bioplex_WMM WMM_only
SELENOT	MGAT2	0.006	0.004	bioplex_WMM WMM_only
SELENOT	B3GALT6	0.006	0.004	bioplex_WMM WMM_only
MOSPD2	SELENON	0.006	0.004	bioplex_WMM WMM_only
SELENOT	SELENON	0.006	0.006	bioplex_WMM WMM_only
MOSPD2	NAT14	0.006	0.004	bioplex_WMM WMM_only
MOSPD2	B3GALT6	0.006	0.002	bioplex_WMM WMM_only
SELENON	MUL1	0.006	0.005	bioplex_WMM WMM_only
MUL1	QPCTL	0.006	0.002	bioplex_WMM WMM_only
PXMP2	QPCTL	0.006	0.006	bioplex_WMM boldt boldt_WMM
PXMP2	NAT14	0.006	0.001	bioplex_WMM boldt boldt_WMM
EXD2	PXMP2	0.006	0.011	bioplex_WMM WMM_only
B3GALT6	MUL1	0.006	0.013	bioplex_WMM WMM_only
EXD2	QPCTL	0.006	0.01	bioplex_WMM WMM_only
NAT14	SELENON	0.006	0.006	bioplex_WMM WMM_only
PXMP2	SELENON	0.006	0.005	bioplex_WMM WMM_only
EXD2	SELENON	0.006	0.002	bioplex_WMM WMM_only
EXD2	NAT14	0.005	0.013	bioplex_WMM WMM_only
PXMP2	MGAT2	0.005	0.006	bioplex_WMM WMM_only
FAM174A	QPCTL	0.005	0.006	bioplex (FAM174A) bioplex_WMM
PXMP2	B3GALT6	0.005	0.013	bioplex_WMM WMM_only
NAT14	QPCTL	0.005	0.008	bioplex_WMM WMM_only boldt_WMM
EXD2	MGAT2	0.005	0.008	bioplex_WMM WMM_only
EXD2	B3GALT6	0.005	0.01	bioplex_WMM WMM_only
MGAT2	SELENON	0.005	0.01	bioplex_WMM WMM_only
MGAT2	QPCTL	0.005	0.013	bioplex_WMM WMM_only
MGAT2	NAT14	0.005	0.011	bioplex_WMM WMM_only
SELENON	QPCTL	0.004	0.013	bioplex_WMM WMM_only
NAT14	B3GALT6	0.004	0.015	bioplex_WMM WMM_only
B3GALT6	QPCTL	0.004	0.013	bioplex_WMM WMM_only
SELENON	B3GALT6	0.004	0.013	bioplex_WMM WMM_only
FAM174A	B3GALT6	0.004	0.009	bioplex (FAM174A) bioplex_WMM
MGAT2	B3GALT6	0.003	0.016	bioplex_WMM WMM_only

Images

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Complex HuMAP2_03515 has an average edge precision of 0.057 which is ranked 6973 out of all 6965 complexes.

Related Complexes

Genename	Complexes
MUL1	HuMAP2_03515 HuMAP2_06608
PEX19	HuMAP2_03515 HuMAP2_03548 HuMAP2_04739
FAM174A	HuMAP2_02479 HuMAP2_03515 HuMAP2_04031
EXOG	HuMAP2_03515
EXD2	HuMAP2_03515 HuMAP2_05127
SELENOT	HuMAP2_01056 HuMAP2_03515 HuMAP2_05923
SELENON	HuMAP2_03515
MARC2	HuMAP2_03515
PXMP2	HuMAP2_03515
NAT14	HuMAP2_03515 HuMAP2_03548
GLCE	HuMAP2_03515 HuMAP2_03612 HuMAP2_03717
RDH12	HuMAP2_03515 HuMAP2_05696
TMEM168	HuMAP2_02479 HuMAP2_03515 HuMAP2_04031
MGAT2	HuMAP2_03515
MOSPD2	HuMAP2_03515
LETMD1	HuMAP2_03515 HuMAP2_04927 HuMAP2_06222
B3GALT6	HuMAP2_03515
PEX16	HuMAP2_03515
HIGD2A	HuMAP2_03515
QPCTL	HuMAP2_03515 HuMAP2_04132

hu.MAP 2.0: Complex View

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Complex: HuMAP2_03515