hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03521
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CEP350 | Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa) | UniProt NCBI |
| TTLL5 | Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5) | UniProt NCBI |
| CEP19 | Centrosomal protein of 19 kDa (Cep19) | UniProt NCBI |
| PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) | UniProt NCBI |
| FGFR1OP | FGFR1 oncogene partner | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005813 | 0.00128791268804 | 1.0 | CEP350 PPP2R3C TTLL5 CEP19 FGFR1OP | centrosome |
| GO:0005815 | 0.00513369498705 | 1.0 | CEP350 PPP2R3C TTLL5 CEP19 FGFR1OP | microtubule organizing center |
| WP:WP4536 | 0.0173052901509 | 0.4 | FGFR1OP CEP19 | Genes related to primary cilium development (based on CRISPR) |
| GO:0015630 | 0.0477475152415 | 1.0 | CEP350 PPP2R3C TTLL5 CEP19 FGFR1OP | microtubule cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FGFR1OP | CEP350 | 1.0 | 0.949 | hein_WMM bioplex (FGFR1OP) bioplex_WMM youn_WMM hein (FGFR1OP) gupta_WMM gupta (FGFR1OP) boldt_WMM |
| FGFR1OP | PPP2R3C | 1.0 | 0.949 | hein_WMM bioplex (FGFR1OP) bioplex_WMM hein (FGFR1OP,PPP2R3C) gupta_WMM gupta (FGFR1OP) boldt_WMM |
| FGFR1OP | CEP19 | 0.873 | 0.805 | bioplex (FGFR1OP) bioplex_WMM gupta (CEP19) |
| PPP2R3C | CEP350 | 0.09 | 0.355 | hein_WMM bioplex_WMM hein (PPP2R3C) gupta_WMM boldt_WMM |
| FGFR1OP | TTLL5 | 0.024 | 0.211 | hein_WMM youn_WMM hein (FGFR1OP) gupta_WMM |
| CEP19 | CEP350 | 0.008 | 0.042 | bioplex_WMM gupta (CEP19) |
| PPP2R3C | TTLL5 | 0.007 | 0.007 | hein_WMM gupta_WMM WMM_only |
| CEP350 | TTLL5 | 0.005 | 0.006 | hein_WMM youn_WMM gupta_WMM WMM_only |
| CEP19 | PPP2R3C | 0.003 | 0.014 | bioplex_WMM gupta (CEP19) |
Images
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Complex HuMAP2_03521 has an average edge precision of 0.371 which is ranked 3632 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CEP350 | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697 |
| TTLL5 | HuMAP2_01902 HuMAP2_03521 HuMAP2_06301 |
| CEP19 | HuMAP2_01733 HuMAP2_03206 HuMAP2_03521 |
| PPP2R3C | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697 |
| FGFR1OP | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 |