hu.MAP 2.0: Complex View

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP1495	5.0398104697e-06	0.5	SHMT2 SHMT1	Glycine Metabolism
KEGG:00670	0.000306120927358	0.5	SHMT2 SHMT1	One carbon pool by folate
GO:0030170	0.000351729129078	0.75	OAT SHMT2 SHMT1	pyridoxal phosphate binding
GO:0070279	0.000351729129078	0.75	OAT SHMT2 SHMT1	vitamin B6 binding
WP:WP241	0.000633595541779	0.5	SHMT2 SHMT1	One Carbon Metabolism
KEGG:01523	0.000649790903665	0.5	SHMT2 SHMT1	Antifolate resistance
WP:WP2525	0.000729007032317	0.5	SHMT2 SHMT1	Trans-sulfuration and one carbon metabolism
KEGG:00630	0.000869408386689	0.5	SHMT2 SHMT1	Glyoxylate and dicarboxylate metabolism
REAC:R-HSA-196757	0.00105460323216	0.5	SHMT2 SHMT1	Metabolism of folate and pterines
KEGG:00260	0.00147979776218	0.5	SHMT2 SHMT1	Glycine, serine and threonine metabolism
WP:WP3940	0.00188734205227	0.5	SHMT2 SHMT1	One carbon metabolism and related pathways
WP:WP176	0.00230460203011	0.5	SHMT2 SHMT1	Folate Metabolism
GO:0004372	0.00270494046827	0.5	SHMT2 SHMT1	glycine hydroxymethyltransferase activity
GO:1904481	0.00270494046827	0.5	SHMT2 SHMT1	response to tetrahydrofolate
GO:1904482	0.00270494046827	0.5	SHMT2 SHMT1	cellular response to tetrahydrofolate
GO:0019264	0.00270494046827	0.5	SHMT2 SHMT1	glycine biosynthetic process from serine
KEGG:01230	0.00494838688052	0.5	SHMT2 SHMT1	Biosynthesis of amino acids
WP:WP4018	0.00527207105384	0.5	SHMT2 SHMT1	Pathways in clear cell renal cell carcinoma
GO:0019842	0.00587743889796	0.75	OAT SHMT2 SHMT1	vitamin binding
GO:0070905	0.00811409485621	0.5	SHMT2 SHMT1	serine binding
GO:0050897	0.00811409485621	0.5	SHMT2 SHMT1	cobalt ion binding
KEGG:01200	0.012776519361	0.5	SHMT2 SHMT1	Carbon metabolism
GO:0006565	0.0162267366884	0.5	SHMT2 SHMT1	L-serine catabolic process
GO:0006545	0.0162267366884	0.5	SHMT2 SHMT1	glycine biosynthetic process
GO:0008652	0.0198185309013	0.75	OAT SHMT2 SHMT1	cellular amino acid biosynthetic process
GO:0043648	0.023464682987	0.75	OAT SHMT2 SHMT1	dicarboxylic acid metabolic process
MIRNA:hsa-miR-3136-3p	0.0241808944481	0.5	LYPLA2 SHMT2	hsa-miR-3136-3p
MIRNA:hsa-miR-7155-3p	0.0241808944481	0.5	LYPLA2 SHMT2	hsa-miR-7155-3p
GO:0016742	0.0270421395626	0.5	SHMT2 SHMT1	hydroxymethyl-, formyl- and related transferase activity
MIRNA:hsa-miR-134-3p	0.0291936286934	0.5	SHMT2 SHMT1	hsa-miR-134-3p
MIRNA:hsa-miR-921	0.0369995799824	0.5	LYPLA2 SHMT1	hsa-miR-921
MIRNA:hsa-miR-7114-5p	0.0381896870696	0.5	SHMT2 SHMT1	hsa-miR-7114-5p
GO:1901606	0.0396936057372	0.75	OAT SHMT2 SHMT1	alpha-amino acid catabolic process
CORUM:7113	0.0499140284799	0.25	SHMT1	ABRAXAS2-SHMT1 complex
CORUM:7114	0.0499140284799	0.25	SHMT2	ABRAXAS2-SHMT2 complex

Protein 1	Protein 2	Score ?	Precision ?	Evidence ?
OAT	SHMT2	0.696	0.718	bioplex_WMM     Guru     youn_WMM     gupta_WMM     fraction     treiber_WMM
SHMT1	OAT	0.581	0.663	Guru     fraction
SHMT2	LYPLA2	0.064	0.348	youn_WMM     gupta_WMM     fraction
SHMT1	LYPLA2	0.048	0.293	youn_WMM     fraction
OAT	LYPLA2	0.025	0.217	youn_WMM     gupta_WMM     fraction
SHMT1	SHMT2	0.0	0.009	bioplex (SHMT1,SHMT2)     bioplex_WMM     youn_WMM     fraction

?

Click to enlarge

Complex HuMAP2_03524 has an average edge precision of 0.375 which is ranked 3588 out of all 6965 complexes.

Genename	Complexes
LYPLA2	HuMAP2_01176 HuMAP2_03524 HuMAP2_03847 HuMAP2_04782 HuMAP2_06518
SHMT2	HuMAP2_01176 HuMAP2_03524 HuMAP2_04645 HuMAP2_06263 HuMAP2_06518 HuMAP2_06907
SHMT1	HuMAP2_00285 HuMAP2_03524 HuMAP2_04782 HuMAP2_06518 HuMAP2_06907
OAT	HuMAP2_00285 HuMAP2_01176 HuMAP2_01672 HuMAP2_02517 HuMAP2_03524 HuMAP2_04782 HuMAP2_06263 HuMAP2_06518 HuMAP2_06907