hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03545
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PHGDH | D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) | UniProt NCBI |
| EPN3 | Epsin-3 (EPS-15-interacting protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0007503 | 0.0497341708567 | 0.5 | PHGDH | Generalized ichthyosis |
| HP:0007525 | 0.0497341708567 | 0.5 | PHGDH | Yellow subcutaneous tissue covered by thin, scaly skin |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EPN3 | PHGDH | 0.86 | 0.796 | bioplex (EPN3) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_03545 has an average edge precision of 0.796 which is ranked 933 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PHGDH | HuMAP2_01176 HuMAP2_02517 HuMAP2_03545 HuMAP2_04645 HuMAP2_05841 HuMAP2_05939 HuMAP2_06263 |
| EPN3 | HuMAP2_00145 HuMAP2_01711 HuMAP2_03545 HuMAP2_04391 HuMAP2_05841 HuMAP2_05939 HuMAP2_06942 |