hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03546
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| XBP1 | X-box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5) (TREB-5) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form] | UniProt NCBI |
| GAST | Gastrin [Cleaved into: Gastrin-71 (Gastrin component I); Gastrin-52 (G52); Big gastrin (Gastrin component II) (Gastrin-34) (G34); Gastrin (Gastrin component III) (Gastrin-17) (G17); Gastrin-14 (G14); Gastrin-6 (G6)] | UniProt NCBI |
| APOC2 | Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2) [Cleaved into: Proapolipoprotein C-II (ProapoC-II)] | UniProt NCBI |
| CROCC | Rootletin (Ciliary rootlet coiled-coil protein) | UniProt NCBI |
| CROCCP2 | NCBI | |
| PEX14 | Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) | UniProt NCBI |
| DSCR4 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1984 | 0.0249780992026 | 0.2 | PEX14 | PEX14 homodimer complex |
| WP:WP2597 | 0.0372906105173 | 0.2 | GAST | Secretion of Hydrochloric Acid in Parietal Cells |
| WP:WP2596 | 0.0372906105173 | 0.2 | GAST | Gastric acid production |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CROCCP2 | CROCC | 1.0 | 0.949 | bioplex (CROCC) bioplex_WMM |
| CROCCP2 | DSCR4 | 0.313 | 0.506 | bioplex (DSCR4) bioplex_WMM |
| APOC2 | DSCR4 | 0.174 | 0.433 | bioplex (DSCR4) bioplex_WMM |
| XBP1 | CROCC | 0.172 | 0.432 | bioplex (CROCC) bioplex_WMM |
| GAST | CROCCP2 | 0.124 | 0.396 | bioplex (GAST) bioplex_WMM |
| APOC2 | GAST | 0.075 | 0.357 | bioplex (GAST) bioplex_WMM |
| CROCC | PEX14 | 0.024 | 0.215 | bioplex (CROCC) bioplex_WMM |
| APOC2 | CROCCP2 | 0.01 | 0.103 | bioplex_WMM WMM_only |
| XBP1 | CROCCP2 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| XBP1 | PEX14 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| CROCCP2 | PEX14 | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03546 has an average edge precision of 0.315 which is ranked 4408 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| XBP1 | HuMAP2_00754 HuMAP2_00951 HuMAP2_01612 HuMAP2_02041 HuMAP2_02581 HuMAP2_03546 HuMAP2_06108 |
| GAST | HuMAP2_01043 HuMAP2_01591 HuMAP2_02581 HuMAP2_03546 |
| APOC2 | HuMAP2_01043 HuMAP2_01591 HuMAP2_02581 HuMAP2_03546 |
| CROCC | HuMAP2_02581 HuMAP2_03278 HuMAP2_03546 HuMAP2_06108 |
| CROCCP2 | HuMAP2_01591 HuMAP2_02581 HuMAP2_03278 HuMAP2_03546 |
| PEX14 | HuMAP2_03546 HuMAP2_05792 |
| DSCR4 | HuMAP2_01591 HuMAP2_02581 HuMAP2_03546 |