hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03547
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IL17RB | Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor) | UniProt NCBI |
| ATG101 | Autophagy-related protein 101 | UniProt NCBI |
| RB1CC1 | RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200) | UniProt NCBI |
| FAM221B | Protein FAM221B | UniProt NCBI |
| SELENOO | Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.n1) (Selenoprotein O) (SelO) | UniProt NCBI |
| ATG13 | Autophagy-related protein 13 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6232 | 9.01288868683e-09 | 0.5 | ATG101 ATG13 RB1CC1 | ULK1-ATG13-RB1CC1-ATG101 complex |
| CORUM:7091 | 9.01288868683e-09 | 0.5 | ATG101 ATG13 RB1CC1 | FIP200-ULK1-ATG13-ATG101 complex |
| CORUM:7065 | 7.88270302729e-08 | 0.5 | ATG101 ATG13 RB1CC1 | WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex |
| WP:WP4577 | 1.84137562659e-05 | 0.5 | ATG101 ATG13 RB1CC1 | Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway |
| CORUM:6229 | 2.51655344529e-05 | 0.333333333333 | RB1CC1 ATG13 | ULK1-ATG13-RB1CC1 complex |
| CORUM:6230 | 2.51655344529e-05 | 0.333333333333 | RB1CC1 ATG13 | ULK2-ATG13-RB1CC1 complex |
| KEGG:04211 | 0.000147172017102 | 0.5 | ATG101 ATG13 RB1CC1 | Longevity regulating pathway |
| REAC:R-HSA-1632852 | 0.000623257676688 | 0.5 | ATG101 ATG13 RB1CC1 | Macroautophagy |
| KEGG:04140 | 0.000632078586851 | 0.5 | ATG101 ATG13 RB1CC1 | Autophagy - animal |
| REAC:R-HSA-9612973 | 0.00103737446705 | 0.5 | ATG101 ATG13 RB1CC1 | Autophagy |
| WP:WP3844 | 0.00241892882621 | 0.333333333333 | RB1CC1 ATG13 | PI3K-AKT-mTOR signaling pathway and therapeutic opportunities |
| KEGG:04136 | 0.00289648020675 | 0.333333333333 | ATG101 ATG13 | Autophagy - other |
| GO:0000407 | 0.00470617323084 | 0.5 | ATG101 ATG13 RB1CC1 | phagophore assembly site |
| GO:0016237 | 0.020283420769 | 0.333333333333 | RB1CC1 ATG13 | lysosomal microautophagy |
| GO:0034727 | 0.020283420769 | 0.333333333333 | RB1CC1 ATG13 | piecemeal microautophagy of the nucleus |
| WP:WP615 | 0.021546686463 | 0.333333333333 | RB1CC1 ATG13 | Senescence and Autophagy in Cancer |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RB1CC1 | FAM221B | 0.234 | 0.47 | bioplex (FAM221B) bioplex_WMM |
| ATG101 | FAM221B | 0.187 | 0.44 | bioplex (FAM221B) bioplex_WMM |
| ATG13 | FAM221B | 0.039 | 0.264 | bioplex (FAM221B) bioplex_WMM |
| FAM221B | SELENOO | 0.038 | 0.266 | bioplex (FAM221B) bioplex_WMM |
| SELENOO | IL17RB | 0.036 | 0.264 | bioplex (IL17RB) bioplex_WMM |
| ATG13 | RB1CC1 | 0.011 | 0.145 | bioplex_WMM WMM_only |
| ATG13 | ATG101 | 0.01 | 0.128 | bioplex_WMM WMM_only |
| RB1CC1 | ATG101 | 0.009 | 0.107 | bioplex_WMM WMM_only |
| ATG101 | SELENOO | 0.008 | 0.01 | bioplex_WMM WMM_only |
| ATG13 | SELENOO | 0.007 | 0.003 | bioplex_WMM WMM_only |
| RB1CC1 | SELENOO | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03547 has an average edge precision of 0.191 which is ranked 6296 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IL17RB | HuMAP2_01414 HuMAP2_03547 |
| ATG101 | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |
| RB1CC1 | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |
| FAM221B | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |
| SELENOO | HuMAP2_01414 HuMAP2_03547 |
| ATG13 | HuMAP2_00117 HuMAP2_03547 HuMAP2_03789 HuMAP2_03911 |