hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03554
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPA2 | Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2) | UniProt NCBI |
| PNP | Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | UniProt NCBI |
| TRAP1 | Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) | UniProt NCBI |
| VCL | Vinculin (Metavinculin) (MV) | UniProt NCBI |
| ECHS1 | Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001639 | 0.0156015562715 | 0.6 | VCL PPA2 ECHS1 | Hypertrophic cardiomyopathy |
| MIRNA:hsa-miR-196a-5p | 0.0196972657695 | 0.6 | PNP TRAP1 VCL | hsa-miR-196a-5p |
| CORUM:6208 | 0.0249780992026 | 0.2 | PNP | PNP homotrimer complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ECHS1 | PNP | 0.447 | 0.592 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PPA2 | ECHS1 | 0.219 | 0.466 | bioplex (PPA2) bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| TRAP1 | VCL | 0.203 | 0.453 | hein_WMM bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| ECHS1 | VCL | 0.157 | 0.416 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ECHS1 | TRAP1 | 0.146 | 0.409 | bioplex (ECHS1) bioplex_WMM Guru boldt fraction boldt_WMM |
| TRAP1 | PNP | 0.116 | 0.387 | bioplex_WMM boldt fraction boldt_WMM |
| PPA2 | TRAP1 | 0.02 | 0.186 | bioplex (PPA2) bioplex_WMM fraction |
| PNP | VCL | 0.008 | 0.091 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PPA2 | PNP | 0.006 | 0.007 | bioplex (PPA2) bioplex_WMM treiber_WMM |
| PPA2 | VCL | 0.0 | 0.0 | bioplex (PPA2) bioplex_WMM fraction |
Images
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Complex HuMAP2_03554 has an average edge precision of 0.301 which is ranked 4580 out of all 6965 complexes.
Related Complexes