hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03564
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) | UniProt NCBI |
| FAM122A | Protein FAM122A | UniProt NCBI |
| PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03015 | 0.0017077231529 | 0.666666666667 | PPP2R2A PPP2R2D | mRNA surveillance pathway |
| KEGG:05142 | 0.0017077231529 | 0.666666666667 | PPP2R2A PPP2R2D | Chagas disease (American trypanosomiasis) |
| GO:0019888 | 0.00212751596192 | 1.0 | FAM122A PPP2R2A PPP2R2D | protein phosphatase regulator activity |
| KEGG:04071 | 0.00262334701465 | 0.666666666667 | PPP2R2A PPP2R2D | Sphingolipid signaling pathway |
| KEGG:04152 | 0.00277005173367 | 0.666666666667 | PPP2R2A PPP2R2D | AMPK signaling pathway |
| KEGG:04728 | 0.00323398213006 | 0.666666666667 | PPP2R2A PPP2R2D | Dopaminergic synapse |
| GO:0019208 | 0.00360649647245 | 1.0 | FAM122A PPP2R2A PPP2R2D | phosphatase regulator activity |
| KEGG:04261 | 0.00367632825889 | 0.666666666667 | PPP2R2A PPP2R2D | Adrenergic signaling in cardiomyocytes |
| KEGG:05160 | 0.00408648948727 | 0.666666666667 | PPP2R2A PPP2R2D | Hepatitis C |
| KEGG:04390 | 0.00445520604942 | 0.666666666667 | PPP2R2A PPP2R2D | Hippo signaling pathway |
| KEGG:04530 | 0.00464549646756 | 0.666666666667 | PPP2R2A PPP2R2D | Tight junction |
| KEGG:04151 | 0.0198175756043 | 0.666666666667 | PPP2R2A PPP2R2D | PI3K-Akt signaling pathway |
| KEGG:05165 | 0.0214257750703 | 0.666666666667 | PPP2R2A PPP2R2D | Human papillomavirus infection |
| WP:WP4172 | 0.0388642175144 | 0.666666666667 | PPP2R2A PPP2R2D | PI3K-Akt Signaling Pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP2R2A | PPP2R2D | 1.0 | 0.949 | hein_WMM bioplex (PPP2R2D) bioplex_WMM boldt hein (PPP2R2D) gupta_WMM boldt_WMM |
| PPP2R2A | FAM122A | 0.935 | 0.85 | hein_WMM bioplex (FAM122A) bioplex_WMM hein (PPP2R2A) |
| PPP2R2D | FAM122A | 0.889 | 0.818 | hein_WMM bioplex (FAM122A,PPP2R2D) bioplex_WMM hein (PPP2R2D) |
Images
Click to enlarge
Complex HuMAP2_03564 has an average edge precision of 0.872 which is ranked 683 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPP2R2D | HuMAP2_01142 HuMAP2_02007 HuMAP2_02812 HuMAP2_03564 HuMAP2_03797 |
| FAM122A | HuMAP2_01142 HuMAP2_02007 HuMAP2_03564 HuMAP2_03797 HuMAP2_04512 HuMAP2_06203 |
| PPP2R2A | HuMAP2_01142 HuMAP2_02007 HuMAP2_03564 HuMAP2_03797 HuMAP2_04512 |