hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03568
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SF3A3 | Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) | UniProt NCBI |
| SF3A1 | Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | UniProt NCBI |
| SF3A2 | Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62) | UniProt NCBI |
| SNRPB2 | U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'') | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1734 | 6.75231048499e-10 | 0.75 | SF3A3 SF3A2 SF3A1 | SF3A1-SF3A2-SF3A3 complex |
| CORUM:2755 | 1.63060294836e-09 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | 17S U2 snRNP |
| CORUM:1181 | 6.46811126422e-08 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | C complex spliceosome |
| GO:0005686 | 7.46504177371e-08 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | U2 snRNP |
| WP:WP411 | 1.46848778508e-07 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | mRNA Processing |
| KEGG:03040 | 2.052638918e-07 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | Spliceosome |
| GO:1903241 | 3.63274304092e-07 | 0.75 | SF3A3 SF3A2 SF3A1 | U2-type prespliceosome assembly |
| CORUM:351 | 6.95120006013e-07 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | Spliceosome |
| REAC:R-HSA-72163 | 3.66683425084e-06 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 4.37825325788e-06 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | mRNA Splicing |
| GO:0071005 | 5.61829777936e-06 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | U2-type precatalytic spliceosome |
| GO:0071011 | 6.09645078186e-06 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | precatalytic spliceosome |
| GO:0000389 | 7.26438828159e-06 | 0.75 | SF3A3 SF3A2 SF3A1 | mRNA 3'-splice site recognition |
| GO:0097525 | 9.63649068965e-06 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | spliceosomal snRNP complex |
| REAC:R-HSA-72203 | 1.12324610099e-05 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0030532 | 1.45315820527e-05 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | small nuclear ribonucleoprotein complex |
| GO:0120114 | 2.80701671762e-05 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | Sm-like protein family complex |
| GO:0071013 | 4.48297714516e-05 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | catalytic step 2 spliceosome |
| GO:0005684 | 6.52012849586e-05 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | U2-type spliceosomal complex |
| GO:0005681 | 0.000657808747052 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | spliceosomal complex |
| REAC:R-HSA-8953854 | 0.000676603019954 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | Metabolism of RNA |
| GO:0006376 | 0.00106129291317 | 0.75 | SF3A3 SF3A2 SF3A1 | mRNA splice site selection |
| GO:0000245 | 0.0080085486554 | 0.75 | SF3A3 SF3A2 SF3A1 | spliceosomal complex assembly |
| GO:0000377 | 0.00944788787297 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.00944788787297 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | mRNA splicing, via spliceosome |
| GO:0000375 | 0.00981835447646 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | RNA splicing, via transesterification reactions |
| GO:0008380 | 0.0187431053955 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | RNA splicing |
| GO:0006397 | 0.0251226492241 | 1.0 | SF3A3 SNRPB2 SF3A2 SF3A1 | mRNA processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SF3A1 | SF3A3 | 1.0 | 0.949 | hein_WMM bioplex (SF3A1) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SF3A2 | SF3A1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SF3A2 | SF3A3 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SNRPB2 | SF3A1 | 0.738 | 0.738 | bioplex (SF3A1) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SNRPB2 | SF3A3 | 0.408 | 0.566 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SNRPB2 | SF3A2 | 0.088 | 0.353 | bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_03568 has an average edge precision of 0.751 which is ranked 1148 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SF3A3 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 HuMAP2_05951 |
| SF3A1 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 HuMAP2_05951 |
| SF3A2 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 |
| SNRPB2 | HuMAP2_00104 HuMAP2_00496 HuMAP2_02497 HuMAP2_03568 HuMAP2_05096 HuMAP2_06616 |