hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03569
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ADD3 | Gamma-adducin (Adducin-like protein 70) | UniProt NCBI |
| ADD2 | Beta-adducin (Erythrocyte adducin subunit beta) | UniProt NCBI |
| ADD1 | Alpha-adducin (Erythrocyte adducin subunit alpha) | UniProt NCBI |
| FAM122B | Protein FAM122B | UniProt NCBI |
| DPPA4 | Developmental pluripotency-associated protein 4 | UniProt NCBI |
| ANKRD29 | Ankyrin repeat domain-containing protein 29 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5223345 | 7.89904848188e-06 | 0.5 | ADD3 ADD1 ADD2 | Miscellaneous transport and binding events |
| GO:0051016 | 0.00175581235783 | 0.5 | ADD3 ADD1 ADD2 | barbed-end actin filament capping |
| GO:0051693 | 0.00206534926206 | 0.5 | ADD3 ADD1 ADD2 | actin filament capping |
| GO:0030507 | 0.00240920978697 | 0.5 | ADD3 ADD1 ADD2 | spectrin binding |
| GO:0030835 | 0.00278918949629 | 0.5 | ADD3 ADD1 ADD2 | negative regulation of actin filament depolymerization |
| GO:0030834 | 0.00734442516369 | 0.5 | ADD3 ADD1 ADD2 | regulation of actin filament depolymerization |
| GO:0030837 | 0.0108183376095 | 0.5 | ADD3 ADD1 ADD2 | negative regulation of actin filament polymerization |
| GO:0030042 | 0.0118307664632 | 0.5 | ADD3 ADD1 ADD2 | actin filament depolymerization |
| GO:1901880 | 0.0192515670318 | 0.5 | ADD3 ADD1 ADD2 | negative regulation of protein depolymerization |
| GO:0032272 | 0.0239073169747 | 0.5 | ADD3 ADD1 ADD2 | negative regulation of protein polymerization |
| GO:0043242 | 0.0332327932613 | 0.5 | ADD3 ADD1 ADD2 | negative regulation of protein complex disassembly |
| GO:1901879 | 0.0422297014162 | 0.5 | ADD3 ADD1 ADD2 | regulation of protein depolymerization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ANKRD29 | ADD3 | 0.998 | 0.941 | bioplex (ANKRD29) bioplex_WMM |
| ADD2 | ANKRD29 | 0.677 | 0.706 | bioplex (ANKRD29) bioplex_WMM |
| ADD2 | ADD1 | 0.587 | 0.662 | bioplex (ADD2) bioplex_WMM gupta_WMM |
| ADD2 | DPPA4 | 0.428 | 0.576 | bioplex (DPPA4) bioplex_WMM |
| FAM122B | ANKRD29 | 0.225 | 0.465 | bioplex (ANKRD29) bioplex_WMM |
| ADD1 | ANKRD29 | 0.165 | 0.421 | bioplex (ANKRD29) bioplex_WMM |
| ADD1 | ADD3 | 0.026 | 0.22 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ADD2 | ADD3 | 0.021 | 0.19 | bioplex (ADD2) bioplex_WMM gupta_WMM |
| ADD1 | DPPA4 | 0.013 | 0.145 | bioplex (DPPA4) bioplex_WMM |
| FAM122B | ADD2 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| FAM122B | ADD3 | 0.007 | 0.009 | bioplex_WMM gupta_WMM WMM_only |
| FAM122B | ADD1 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_03569 has an average edge precision of 0.362 which is ranked 3727 out of all 6965 complexes.
Related Complexes