hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03582
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CORO6 | Coronin-6 (Coronin-like protein E) (Clipin-E) | UniProt NCBI |
| ABLIM1 | Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin) | UniProt NCBI |
| CORO1C | Coronin-1C (Coronin-3) (hCRNN4) | UniProt NCBI |
| SYNPO | Synaptopodin | UniProt NCBI |
| CTTN | Src substrate cortactin (Amplaxin) (Oncogene EMS1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003779 | 8.42713009363e-05 | 1.0 | SYNPO CTTN CORO1C ABLIM1 CORO6 | actin binding |
| GO:0051015 | 0.00196556700855 | 0.8 | ABLIM1 CTTN CORO1C CORO6 | actin filament binding |
| GO:0008092 | 0.0125790618987 | 1.0 | SYNPO CTTN CORO1C ABLIM1 CORO6 | cytoskeletal protein binding |
| GO:0097581 | 0.022411068229 | 0.6 | ABLIM1 CORO1C CTTN | lamellipodium organization |
| GO:0007015 | 0.0341905711955 | 0.8 | SYNPO CTTN CORO1C CORO6 | actin filament organization |
| KEGG:04530 | 0.0439700127241 | 0.4 | SYNPO CTTN | Tight junction |
| CORUM:1130 | 0.0499494897235 | 0.2 | CTTN | Hip1R-cortactin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CORO6 | CORO1C | 0.331 | 0.521 | bioplex (CORO1C,CORO6) bioplex_WMM youn_WMM |
| CTTN | CORO1C | 0.059 | 0.333 | hein_WMM bioplex_WMM boldt hein (CORO1C) gupta_WMM boldt_WMM treiber_WMM |
| SYNPO | CORO1C | 0.051 | 0.296 | hein_WMM hein (CORO1C) |
| ABLIM1 | CORO1C | 0.045 | 0.286 | hein_WMM bioplex_WMM youn_WMM hein (CORO1C) gupta_WMM |
| CORO6 | ABLIM1 | 0.007 | 0.002 | youn_WMM WMM_only |
| CTTN | CORO6 | 0.007 | 0.002 | WMM_only |
| SYNPO | ABLIM1 | 0.005 | 0.006 | hein_WMM WMM_only |
| CTTN | SYNPO | 0.005 | 0.011 | hein_WMM WMM_only |
| CTTN | ABLIM1 | 0.004 | 0.015 | hein_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_03582 has an average edge precision of 0.164 which is ranked 6591 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CORO6 | HuMAP2_01757 HuMAP2_02262 HuMAP2_02531 HuMAP2_03582 HuMAP2_04613 |
| ABLIM1 | HuMAP2_02789 HuMAP2_03582 HuMAP2_05994 HuMAP2_06814 |
| CORO1C | HuMAP2_03582 HuMAP2_04442 HuMAP2_04615 HuMAP2_06976 |
| SYNPO | HuMAP2_02178 HuMAP2_03582 HuMAP2_04615 HuMAP2_05394 HuMAP2_05638 |
| CTTN | HuMAP2_00558 HuMAP2_03582 HuMAP2_04615 |