hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03597
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CA10 | Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CA-RP X) (CARP X) (Cerebral protein 15) | UniProt NCBI |
| MTERF4 | Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (mTERF domain-containing protein 2) [Cleaved into: mTERF domain-containing protein 2 processed] | UniProt NCBI |
| INSL3 | Insulin-like 3 (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain] | UniProt NCBI |
| TOR1AIP1 | Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B) | UniProt NCBI |
| ASS1 | Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) | UniProt NCBI |
| PIAS4 | E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (RING-type E3 ubiquitin transferase PIAS4) | UniProt NCBI |
| CHCHD4 | Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | UniProt NCBI |
| PPRC1 | Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC) | UniProt NCBI |
| NSUN4 | 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) | UniProt NCBI |
| UNC13D | Protein unc-13 homolog D (Munc13-4) | UniProt NCBI |
| G6PD | Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6793080 | 0.0016286415525 | 0.181818181818 | MTERF4 NSUN4 | rRNA modification in the mitochondrion |
| REAC:R-HSA-8868766 | 0.00487805524375 | 0.181818181818 | MTERF4 NSUN4 | rRNA processing in the mitochondrion |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PIAS4 | CA10 | 0.959 | 0.864 | bioplex (CA10) bioplex_WMM |
| PPRC1 | CA10 | 0.202 | 0.452 | bioplex (CA10) bioplex_WMM |
| MTERF4 | CA10 | 0.162 | 0.418 | bioplex (CA10) bioplex_WMM |
| ASS1 | CA10 | 0.077 | 0.352 | bioplex (CA10) bioplex_WMM |
| NSUN4 | CA10 | 0.06 | 0.336 | bioplex (CA10) bioplex_WMM |
| TOR1AIP1 | CA10 | 0.043 | 0.272 | bioplex (CA10) bioplex_WMM |
| CHCHD4 | TOR1AIP1 | 0.042 | 0.269 | hein_WMM bioplex (TOR1AIP1) bioplex_WMM hein (TOR1AIP1) |
| G6PD | CA10 | 0.036 | 0.264 | bioplex (CA10) bioplex_WMM |
| NSUN4 | INSL3 | 0.026 | 0.221 | bioplex (INSL3) bioplex_WMM |
| UNC13D | G6PD | 0.021 | 0.184 | fraction |
| MTERF4 | NSUN4 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| PPRC1 | PIAS4 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| ASS1 | PIAS4 | 0.009 | 0.101 | bioplex_WMM WMM_only |
| MTERF4 | PIAS4 | 0.009 | 0.089 | bioplex_WMM WMM_only |
| ASS1 | PPRC1 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| MTERF4 | PPRC1 | 0.008 | 0.095 | bioplex_WMM WMM_only |
| NSUN4 | PIAS4 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| MTERF4 | ASS1 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| PPRC1 | NSUN4 | 0.008 | 0.064 | bioplex_WMM WMM_only |
| PIAS4 | G6PD | 0.008 | 0.032 | bioplex_WMM WMM_only |
| TOR1AIP1 | PIAS4 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| ASS1 | NSUN4 | 0.008 | 0.022 | bioplex_WMM youn_WMM WMM_only |
| PPRC1 | G6PD | 0.007 | 0.009 | bioplex_WMM WMM_only |
| TOR1AIP1 | PPRC1 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| MTERF4 | G6PD | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TOR1AIP1 | ASS1 | 0.007 | 0.006 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MTERF4 | TOR1AIP1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| CHCHD4 | INSL3 | 0.007 | 0.004 | youn_WMM WMM_only |
| ASS1 | G6PD | 0.007 | 0.004 | bioplex_WMM WMM_only treiber_WMM |
| TOR1AIP1 | NSUN4 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| CHCHD4 | ASS1 | 0.006 | 0.001 | bioplex (ASS1) |
| NSUN4 | G6PD | 0.006 | 0.01 | bioplex_WMM WMM_only |
| TOR1AIP1 | G6PD | 0.006 | 0.003 | bioplex_WMM WMM_only |
| CHCHD4 | G6PD | 0.005 | 0.011 | bioplex_WMM WMM_only |
| MTERF4 | INSL3 | 0.0 | 0.007 | bioplex (INSL3) bioplex_WMM |
Images
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Complex HuMAP2_03597 has an average edge precision of 0.133 which is ranked 6818 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CA10 | HuMAP2_03597 HuMAP2_04139 HuMAP2_04905 HuMAP2_05911 |
| MTERF4 | HuMAP2_01891 HuMAP2_03597 HuMAP2_04459 |
| INSL3 | HuMAP2_03597 |
| TOR1AIP1 | HuMAP2_02046 HuMAP2_02740 HuMAP2_03597 HuMAP2_04590 HuMAP2_05271 |
| ASS1 | HuMAP2_02860 HuMAP2_03597 HuMAP2_04905 HuMAP2_05668 HuMAP2_05911 |
| PIAS4 | HuMAP2_03597 HuMAP2_04139 HuMAP2_04905 HuMAP2_05911 |
| CHCHD4 | HuMAP2_02046 HuMAP2_02740 HuMAP2_02864 HuMAP2_03597 HuMAP2_04590 HuMAP2_05271 |
| PPRC1 | HuMAP2_02924 HuMAP2_03597 HuMAP2_04905 HuMAP2_05911 |
| NSUN4 | HuMAP2_03597 HuMAP2_04905 |
| UNC13D | HuMAP2_03597 |
| G6PD | HuMAP2_03597 |