hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03603
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IFT122 | Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140) | UniProt NCBI |
| WDR35 | WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog) | UniProt NCBI |
| WDR19 | WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) | UniProt NCBI |
| IFT140 | Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) | UniProt NCBI |
| IFT43 | Intraflagellar transport protein 43 homolog | UniProt NCBI |
| C11orf74 | Protein C11orf74 (Protein HEPIS) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030991 | 1.03206737618e-12 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | intraciliary transport particle A |
| CORUM:6585 | 2.26981451009e-12 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Intraflagellar transport complex A |
| WP:WP4532 | 3.27530587254e-12 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Intraflagellar transport proteins binding to dynein |
| GO:0035721 | 2.27003984279e-11 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | intraciliary retrograde transport |
| REAC:R-HSA-5620924 | 3.7758267894e-10 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Intraflagellar transport |
| GO:0030990 | 2.60849957036e-09 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | intraciliary transport particle |
| WP:WP4536 | 3.53651939717e-09 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Genes related to primary cilium development (based on CRISPR) |
| HP:0000691 | 3.1483575991e-08 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Microdontia |
| GO:0035735 | 3.22787683477e-08 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | intraciliary transport involved in cilium assembly |
| HP:0000774 | 3.32115744447e-08 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Narrow chest |
| HP:0000968 | 4.31117379363e-08 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Ectodermal dysplasia |
| GO:0097542 | 5.32624788388e-08 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | ciliary tip |
| HP:0005257 | 6.64486861709e-08 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Thoracic hypoplasia |
| GO:0042073 | 1.03878083327e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | intraciliary transport |
| HP:0001363 | 1.07861441229e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Craniosynostosis |
| HP:0011071 | 1.45771154714e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of permanent molar morphology |
| HP:0006479 | 1.45771154714e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of the dental pulp |
| HP:0000679 | 1.45771154714e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Taurodontia |
| HP:0000268 | 1.67727324635e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Dolichocephaly |
| HP:0011077 | 1.87954064695e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of molar |
| HP:0011070 | 1.87954064695e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of molar morphology |
| HP:0006486 | 1.87954064695e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of the dental root |
| GO:0099118 | 2.67615521812e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | microtubule-based protein transport |
| GO:0098840 | 2.67615521812e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | protein transport along microtubule |
| REAC:R-HSA-5617833 | 3.20449539048e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Cilium Assembly |
| HP:0008499 | 3.70149038815e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | High hypermetropia |
| HP:0000269 | 4.99675465005e-07 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Prominent occiput |
| HP:0000944 | 5.18875554541e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the metaphysis |
| HP:0009803 | 5.51439437395e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Short phalanx of finger |
| HP:0006482 | 6.59047852865e-07 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of dental morphology |
| HP:0009826 | 1.02982589712e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Limb undergrowth |
| HP:0009767 | 1.02982589712e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Aplasia/Hypoplasia of the phalanges of the hand |
| HP:0000773 | 1.18434459557e-06 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Short ribs |
| HP:0000687 | 1.71505595176e-06 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Widely spaced teeth |
| HP:0008905 | 1.71505595176e-06 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Rhizomelia |
| HP:0000772 | 1.97164622717e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the ribs |
| REAC:R-HSA-1852241 | 2.15632898754e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Organelle biogenesis and maintenance |
| HP:0011329 | 2.64946781006e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of cranial sutures |
| HP:0001156 | 5.12786393605e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Brachydactyly |
| HP:0000601 | 5.45924295507e-06 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Hypotelorism |
| HP:0004442 | 5.76330785731e-06 | 0.5 | IFT122 WDR19 IFT43 | Sagittal craniosynostosis |
| HP:0001547 | 5.85998338004e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the rib cage |
| HP:0012622 | 6.3781831231e-06 | 0.666666666667 | IFT122 WDR19 IFT140 IFT43 | Chronic kidney disease |
| HP:0011217 | 6.3781831231e-06 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal shape of the occiput |
| REAC:R-HSA-5610787 | 7.10312736365e-06 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Hedgehog 'off' state |
| HP:0008873 | 7.40834097508e-06 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Disproportionate short-limb short stature |
| HP:0011218 | 7.7106359991e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal shape of the frontal region |
| HP:0002007 | 7.7106359991e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Frontal bossing |
| HP:0000083 | 8.13127651204e-06 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Renal insufficiency |
| HP:0006712 | 8.1611328265e-06 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Aplasia/Hypoplasia of the ribs |
| HP:0001159 | 1.03434504041e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Syndactyly |
| HP:0000235 | 1.08746629409e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the fontanelles or cranial sutures |
| HP:0002983 | 1.22794365743e-05 | 0.666666666667 | IFT140 IFT43 WDR35 WDR19 | Micromelia |
| GO:0010970 | 1.3434313138e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | transport along microtubule |
| HP:0004207 | 1.43115920248e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal 5th finger morphology |
| HP:0000232 | 1.45393002531e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Everted lower lip vermilion |
| HP:0001395 | 1.51498453027e-05 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Hepatic fibrosis |
| HP:0003498 | 1.70970033575e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Disproportionate short stature |
| REAC:R-HSA-5358351 | 1.91901372307e-05 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Signaling by Hedgehog |
| HP:0012472 | 1.92257179205e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Eclabion |
| HP:0000766 | 1.94110265633e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the sternum |
| HP:0030799 | 1.95090261981e-05 | 0.5 | IFT122 IFT43 IFT140 | Scaphocephaly |
| HP:0008388 | 2.07510933131e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal toenail morphology |
| GO:0099111 | 2.3458390775e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | microtubule-based transport |
| HP:0009882 | 2.77748962842e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Short distal phalanx of finger |
| HP:0100259 | 2.87637479698e-05 | 0.666666666667 | IFT140 IFT43 WDR35 WDR19 | Postaxial polydactyly |
| HP:0009835 | 3.08202506509e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Aplasia/Hypoplasia of the distal phalanges of the hand |
| GO:0030705 | 3.08409640217e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | cytoskeleton-dependent intracellular transport |
| HP:0000540 | 4.4164150935e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Hypermetropia |
| GO:0061512 | 4.49707918505e-05 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | protein localization to cilium |
| HP:0011927 | 4.50018607965e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Short digit |
| HP:0006711 | 4.55612594662e-05 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Aplasia/Hypoplasia involving bones of the thorax |
| HP:0000668 | 5.30491233787e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Hypodontia |
| HP:0000682 | 5.96732202416e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of dental enamel |
| HP:0001231 | 6.68974624104e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal fingernail morphology |
| HP:0000463 | 7.07668399696e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Anteverted nares |
| HP:3000050 | 7.273048387e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of odontoid tissue |
| HP:0009832 | 7.47568100119e-05 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal distal phalanx morphology of finger |
| HP:0005288 | 8.09759161048e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the nares |
| HP:0045060 | 8.93773655313e-05 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Aplasia/hypoplasia involving bones of the extremities |
| HP:0006101 | 0.000110510255927 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Finger syndactyly |
| HP:0005692 | 0.000124871018367 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Joint hyperflexibility |
| HP:0011314 | 0.000127608081425 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of long bone morphology |
| HP:0009815 | 0.000130207948638 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Aplasia/hypoplasia of the extremities |
| HP:0000429 | 0.000142435415529 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the nasal alae |
| HP:0000090 | 0.000143381531621 | 0.5 | IFT140 WDR19 IFT43 | Nephronophthisis |
| HP:0005918 | 0.000146708649501 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal finger phalanx morphology |
| HP:0012211 | 0.000148155559522 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal renal physiology |
| HP:0010306 | 0.000230325766317 | 0.5 | IFT140 WDR35 WDR19 | Short thorax |
| HP:0006494 | 0.00023746147761 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Aplasia/Hypoplasia involving bones of the feet |
| GO:0031503 | 0.000243760878037 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | protein-containing complex localization |
| GO:0007018 | 0.000260256231992 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | microtubule-based movement |
| HP:0000939 | 0.000262695155171 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Osteoporosis |
| HP:0010442 | 0.000262695155171 | 0.666666666667 | IFT140 IFT43 WDR35 WDR19 | Polydactyly |
| HP:0100957 | 0.000265636855275 | 0.5 | IFT140 WDR19 IFT43 | Abnormal renal medulla morphology |
| HP:0000178 | 0.000331404976924 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of lower lip |
| HP:0000940 | 0.00034404492279 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal diaphysis morphology |
| HP:0009381 | 0.000350498256174 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Short finger |
| HP:0009804 | 0.000357041589874 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Reduced number of teeth |
| HP:0002648 | 0.000374349857348 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of calvarial morphology |
| HP:0000692 | 0.000398238023921 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Misalignment of teeth |
| HP:0000767 | 0.000427608120903 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Pectus excavatum |
| HP:0004209 | 0.00043519666828 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Clinodactyly of the 5th finger |
| HP:0009179 | 0.000450675026624 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Deviation of the 5th finger |
| HP:0008070 | 0.000458566576442 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Sparse hair |
| HP:0001382 | 0.000482861216719 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Joint hypermobility |
| HP:0410042 | 0.000497378279494 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal liver morphology |
| HP:0000765 | 0.000524659709911 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the thorax |
| HP:0006483 | 0.000525472050521 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal number of teeth |
| HP:0011061 | 0.000561533098737 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of dental structure |
| HP:0011357 | 0.000561533098737 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of hair density |
| HP:0000164 | 0.000574192448674 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the dentition |
| HP:0040019 | 0.000629046311597 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Finger clinodactyly |
| HP:0006265 | 0.000639163727168 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Aplasia/Hypoplasia of fingers |
| HP:0010938 | 0.000650669916921 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the external nose |
| HP:0006493 | 0.000691584689095 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Aplasia/hypoplasia involving bones of the lower limbs |
| HP:0002213 | 0.000756496387193 | 0.5 | IFT122 WDR35 IFT43 | Fine hair |
| HP:0000545 | 0.000770283954671 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Myopia |
| HP:0000290 | 0.000772231846415 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the forehead |
| HP:0002683 | 0.000788617661526 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the calvaria |
| HP:0012210 | 0.0008510845822 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal renal morphology |
| HP:0005105 | 0.000856953137455 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal nasal morphology |
| HP:0003774 | 0.000873314294634 | 0.5 | IFT140 WDR19 IFT43 | Stage 5 chronic kidney disease |
| HP:0005922 | 0.00101765014738 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal hand morphology |
| HP:0000639 | 0.00107651099983 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Nystagmus |
| HP:0006644 | 0.00112625143517 | 0.333333333333 | WDR35 WDR19 | Thoracic dysplasia |
| HP:0012547 | 0.00114894594913 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal involuntary eye movements |
| HP:0011277 | 0.00118659007425 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the urinary system physiology |
| HP:0000973 | 0.00129428949367 | 0.5 | IFT43 WDR35 WDR19 | Cutis laxa |
| GO:0060271 | 0.00130841386785 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | cilium assembly |
| HP:0001392 | 0.00138982123449 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the liver |
| GO:0044441 | 0.00150358061646 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | ciliary part |
| HP:0004097 | 0.00160229059062 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Deviation of finger |
| HP:0001167 | 0.0016100974522 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of finger |
| HP:0009115 | 0.00167931497848 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Aplasia/hypoplasia involving the skeleton |
| GO:0044782 | 0.00169595706398 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | cilium organization |
| HP:0009484 | 0.00183629101111 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Deviation of the hand or of fingers of the hand |
| HP:0001597 | 0.00188142954639 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of the nail |
| HP:0001162 | 0.00211215101544 | 0.5 | IFT140 WDR35 WDR19 | Postaxial hand polydactyly |
| WP:WP4352 | 0.00227681258456 | 0.5 | IFT122 IFT43 IFT140 | Ciliary landscape |
| HP:0000293 | 0.00241935032153 | 0.5 | IFT122 WDR35 WDR19 | Full cheeks |
| HP:0030084 | 0.00246208950628 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Clinodactyly |
| HP:0004349 | 0.0025466367478 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Reduced bone mineral density |
| HP:0005927 | 0.00269233158637 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Aplasia/hypoplasia involving bones of the hand |
| HP:0001799 | 0.00270155144475 | 0.333333333333 | IFT122 IFT43 | Short nail |
| HP:0001773 | 0.00293356764265 | 0.5 | IFT140 WDR35 WDR19 | Short foot |
| HP:0000286 | 0.00306728865182 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Epicanthus |
| HP:0002012 | 0.00313171112549 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the abdominal organs |
| HP:0000077 | 0.00326601354296 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the kidney |
| HP:0000539 | 0.00344395136497 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of refraction |
| HP:0006496 | 0.00373876477543 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Aplasia/hypoplasia involving bones of the upper limbs |
| HP:0010935 | 0.00375347227765 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the upper urinary tract |
| HP:0001760 | 0.00388883454292 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the foot |
| HP:0004322 | 0.00392821369626 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Short stature |
| HP:0008067 | 0.00416939096982 | 0.5 | IFT43 WDR35 WDR19 | Abnormally lax or hyperextensible skin |
| HP:0011297 | 0.00427590240036 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal digit morphology |
| GO:0005929 | 0.00430914744721 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | cilium |
| HP:0004348 | 0.00442722143038 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of bone mineral density |
| HP:0000506 | 0.00464723136975 | 0.5 | IFT122 WDR35 IFT43 | Telecanthus |
| HP:0002644 | 0.00506157887206 | 0.666666666667 | IFT140 IFT43 WDR35 WDR19 | Abnormality of pelvic girdle bone morphology |
| HP:0001155 | 0.00536595932357 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the hand |
| HP:0000002 | 0.00549380780319 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of body height |
| HP:0003549 | 0.00581053704408 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of connective tissue |
| HP:0006703 | 0.00585204575124 | 0.5 | IFT140 WDR35 WDR19 | Aplasia/Hypoplasia of the lungs |
| HP:0001407 | 0.00682280818411 | 0.333333333333 | IFT122 WDR19 | Hepatic cysts |
| GO:0120031 | 0.0069705370833 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | plasma membrane bounded cell projection assembly |
| GO:0030031 | 0.00770054580513 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | cell projection assembly |
| HP:0002817 | 0.00802906529576 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the upper limb |
| HP:0002813 | 0.0084565121287 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of limb bone morphology |
| HP:0040068 | 0.0084565121287 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of limb bone |
| HP:0010719 | 0.00865912215453 | 0.5 | IFT122 WDR35 IFT43 | Abnormality of hair texture |
| HP:0001780 | 0.00878617267619 | 0.666666666667 | IFT122 WDR19 IFT140 IFT43 | Abnormality of toe |
| HP:0011849 | 0.0089304858519 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal bone ossification |
| HP:0009836 | 0.00899388668352 | 0.333333333333 | IFT122 WDR19 | Broad distal phalanx of finger |
| HP:0002814 | 0.00928699225478 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the lower limb |
| HP:0002652 | 0.00982946309918 | 0.5 | IFT140 WDR35 WDR19 | Skeletal dysplasia |
| HP:0001970 | 0.0101912456166 | 0.333333333333 | IFT122 WDR19 | Tubulointerstitial nephritis |
| HP:0000496 | 0.0103505989336 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of eye movement |
| HP:0000366 | 0.0106092506178 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the nose |
| HP:0010647 | 0.0106650876034 | 0.5 | IFT43 WDR35 WDR19 | Abnormal elasticity of skin |
| HP:0040069 | 0.0108030411913 | 0.666666666667 | IFT122 WDR35 IFT140 WDR19 | Abnormal lower limb bone morphology |
| HP:0001161 | 0.0113217289996 | 0.5 | IFT140 WDR35 WDR19 | Hand polydactyly |
| HP:0001388 | 0.0115464072696 | 0.5 | IFT122 WDR35 IFT43 | Joint laxity |
| HP:0011844 | 0.0121735652911 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal appendicular skeleton morphology |
| HP:0004426 | 0.0129566396101 | 0.5 | IFT122 WDR35 WDR19 | Abnormality of the cheek |
| HP:0003330 | 0.0139359737399 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal bone structure |
| HP:0001510 | 0.0145196622671 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Growth delay |
| HP:0009997 | 0.0169695716892 | 0.5 | IFT140 WDR35 WDR19 | Duplication of phalanx of hand |
| HP:0004275 | 0.0172629242154 | 0.5 | IFT140 WDR35 WDR19 | Duplication of hand bones |
| HP:0009142 | 0.0172629242154 | 0.5 | IFT140 WDR35 WDR19 | Duplication of bones involving the upper extremities |
| HP:0011121 | 0.0218588319821 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of skin morphology |
| HP:0000079 | 0.0225628646024 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the urinary system |
| HP:0009122 | 0.0228855434819 | 0.666666666667 | IFT122 WDR35 IFT140 IFT43 | Aplasia/hypoplasia affecting bones of the axial skeleton |
| HP:0007401 | 0.0262553193116 | 0.333333333333 | IFT140 WDR19 | Macular atrophy |
| HP:0005930 | 0.0265015994402 | 0.5 | IFT122 WDR19 IFT140 | Abnormality of epiphysis morphology |
| HP:0000163 | 0.027635799518 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal oral cavity morphology |
| HP:0031816 | 0.027635799518 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal oral morphology |
| HP:0000107 | 0.028507232728 | 0.5 | IFT140 WDR35 IFT43 | Renal cyst |
| HP:0000951 | 0.0311492674319 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the skin |
| HP:0006706 | 0.032521154219 | 0.333333333333 | IFT122 WDR19 | Cystic liver disease |
| HP:0100886 | 0.0353157942626 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormality of globe location |
| HP:0011354 | 0.0367454103886 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Generalized abnormality of skin |
| GO:0007017 | 0.0374033126654 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | microtubule-based process |
| HP:0000153 | 0.0385037006662 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of the mouth |
| HP:0040064 | 0.0417522324256 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormality of limbs |
| HP:0000159 | 0.0426637093966 | 0.666666666667 | IFT122 IFT43 WDR35 WDR19 | Abnormal lip morphology |
| HP:0002088 | 0.0431284498901 | 0.666666666667 | IFT140 IFT43 WDR35 WDR19 | Abnormal lung morphology |
| HP:0000476 | 0.044443111782 | 0.333333333333 | WDR35 IFT43 | Cystic hygroma |
| HP:0000556 | 0.0448473615684 | 0.5 | IFT122 WDR19 IFT140 | Retinal dystrophy |
| HP:0000929 | 0.0467452239687 | 0.833333333333 | IFT122 IFT43 WDR35 IFT140 WDR19 | Abnormal skull morphology |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR35 | C11orf74 | 1.0 | 0.949 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| WDR35 | IFT43 | 0.999 | 0.949 | bioplex (IFT43) bioplex_WMM boldt (IFT43,WDR35) boldt_WMM |
| WDR19 | IFT43 | 0.988 | 0.902 | bioplex (IFT43) bioplex_WMM boldt (IFT43,WDR19) boldt_WMM |
| IFT140 | IFT43 | 0.983 | 0.898 | bioplex (IFT43) bioplex_WMM boldt (IFT140,IFT43) boldt_WMM |
| IFT43 | IFT122 | 0.951 | 0.858 | bioplex (IFT122,IFT43) bioplex_WMM boldt (IFT122,IFT43) boldt_WMM |
| C11orf74 | IFT43 | 0.945 | 0.856 | bioplex (C11orf74,IFT43) bioplex_WMM boldt boldt_WMM |
| C11orf74 | IFT140 | 0.863 | 0.8 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| WDR19 | IFT122 | 0.796 | 0.762 | bioplex (IFT122) bioplex_WMM boldt (IFT122,WDR19) boldt_WMM |
| WDR19 | C11orf74 | 0.789 | 0.758 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| C11orf74 | IFT122 | 0.782 | 0.756 | bioplex (C11orf74) bioplex_WMM boldt (IFT122) boldt_WMM |
| IFT140 | IFT122 | 0.72 | 0.732 | bioplex (IFT122) bioplex_WMM boldt (IFT122,IFT140) boldt_WMM |
| WDR35 | IFT122 | 0.656 | 0.695 | bioplex (IFT122) bioplex_WMM boldt (IFT122,WDR35) boldt_WMM |
| WDR35 | WDR19 | 0.069 | 0.349 | bioplex_WMM boldt (WDR19,WDR35) boldt_WMM |
| WDR19 | IFT140 | 0.011 | 0.141 | bioplex_WMM boldt (IFT140,WDR19) fraction boldt_WMM |
| WDR35 | IFT140 | 0.0 | 0.001 | bioplex_WMM boldt (IFT140,WDR35) fraction boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_03603 has an average edge precision of 0.694 which is ranked 1400 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IFT122 | HuMAP2_01229 HuMAP2_03603 |
| WDR35 | HuMAP2_01229 HuMAP2_03603 |
| WDR19 | HuMAP2_01229 HuMAP2_03603 |
| IFT140 | HuMAP2_01229 HuMAP2_01474 HuMAP2_03603 |
| IFT43 | HuMAP2_01229 HuMAP2_03603 HuMAP2_05938 |
| C11orf74 | HuMAP2_01229 HuMAP2_03603 |