hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03612
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | UniProt NCBI |
| ALG11 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase) | UniProt NCBI |
| GLCE | D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) | UniProt NCBI |
| FADS3 | Fatty acid desaturase 3 (EC 1.14.19.-) (Delta(13) fatty acid desaturase) (Delta(13) desaturase) | UniProt NCBI |
| ALG14 | UDP-N-acetylglucosamine transferase subunit ALG14 homolog | UniProt NCBI |
| GP1BB | Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4521 | 0.00140863716749 | 0.333333333333 | ALG11 ALG14 | Glycosylation and related congenital defects |
| REAC:R-HSA-3781860 | 0.0030072528049 | 0.333333333333 | ALG11 ALG14 | Diseases associated with N-glycosylation of proteins |
| KEGG:00513 | 0.00392074818894 | 0.333333333333 | ALG11 ALG14 | Various types of N-glycan biosynthesis |
| KEGG:00510 | 0.00587890830807 | 0.333333333333 | ALG11 ALG14 | N-Glycan biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FADS3 | ALG14 | 0.189 | 0.441 | bioplex (FADS3) bioplex_WMM |
| HAUS7 | ALG14 | 0.155 | 0.416 | bioplex (HAUS7) bioplex_WMM |
| HAUS7 | GP1BB | 0.047 | 0.292 | bioplex (HAUS7) bioplex_WMM |
| HAUS7 | ALG11 | 0.035 | 0.262 | bioplex (HAUS7) bioplex_WMM |
| HAUS7 | GLCE | 0.026 | 0.22 | bioplex (HAUS7) bioplex_WMM |
| ALG14 | GLCE | 0.008 | 0.094 | bioplex_WMM WMM_only |
| ALG14 | GP1BB | 0.007 | 0.009 | bioplex_WMM WMM_only |
| GLCE | ALG11 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| ALG14 | ALG11 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| GLCE | GP1BB | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ALG11 | GP1BB | 0.004 | 0.012 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03612 has an average edge precision of 0.16 which is ranked 6630 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HAUS7 | HuMAP2_00474 HuMAP2_03612 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| ALG11 | HuMAP2_03612 HuMAP2_05337 |
| GLCE | HuMAP2_03515 HuMAP2_03612 HuMAP2_03717 |
| FADS3 | HuMAP2_03047 HuMAP2_03612 |
| ALG14 | HuMAP2_03047 HuMAP2_03612 |
| GP1BB | HuMAP2_03612 HuMAP2_05337 HuMAP2_06334 |