hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03618
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PKN1 | Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N) | UniProt NCBI |
| ATP7A | Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) | UniProt NCBI |
| KIF5A | Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) | UniProt NCBI |
| COG6 | Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005293 | 0.0142767163782 | 0.5 | ATP7A KIF5A | Venous insufficiency |
| HP:0002028 | 0.0195010181256 | 0.5 | COG6 ATP7A | Chronic diarrhea |
| HP:0002624 | 0.0360996225593 | 0.5 | ATP7A KIF5A | Abnormal venous morphology |
| CORUM:6526 | 0.0499140284799 | 0.25 | KIF5A | SPG10-SPG33 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| COG6 | PKN1 | 0.401 | 0.561 | bioplex (COG6) bioplex_WMM |
| COG6 | ATP7A | 0.321 | 0.512 | bioplex (COG6) bioplex_WMM |
| COG6 | KIF5A | 0.064 | 0.347 | bioplex (COG6) bioplex_WMM boldt_WMM |
| PKN1 | KIF5A | 0.008 | 0.015 | bioplex_WMM gupta_WMM WMM_only |
| PKN1 | ATP7A | 0.007 | 0.005 | bioplex_WMM WMM_only |
| ATP7A | KIF5A | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03618 has an average edge precision of 0.241 which is ranked 5516 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PKN1 | HuMAP2_02575 HuMAP2_03618 HuMAP2_06782 |
| ATP7A | HuMAP2_02575 HuMAP2_03618 HuMAP2_05817 |
| KIF5A | HuMAP2_03618 HuMAP2_06530 |
| COG6 | HuMAP2_01954 HuMAP2_02575 HuMAP2_03618 HuMAP2_05817 |