hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03637
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK12 | Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12) | UniProt NCBI |
| YBX3 | Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB) | UniProt NCBI |
| SCAF4 | SR-related and CTD-associated factor 4 (CTD-binding SR-like protein RA4) (Splicing factor, arginine/serine-rich 15) | UniProt NCBI |
| CCNK | Cyclin-K | UniProt NCBI |
| PRR11 | Proline-rich protein 11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002944 | 0.00450823411379 | 0.4 | CCNK CDK12 | cyclin K-CDK12 complex |
| REAC:R-HSA-6796648 | 0.0253191001807 | 0.4 | CCNK CDK12 | TP53 Regulates Transcription of DNA Repair Genes |
| CORUM:1083 | 0.0499494897235 | 0.2 | CCNK | P-TEFb.4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCNK | CDK12 | 0.424 | 0.575 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| CDK12 | SCAF4 | 0.164 | 0.42 | bioplex_WMM youn_WMM gupta_WMM fraction |
| SCAF4 | YBX3 | 0.055 | 0.305 | bioplex_WMM youn_WMM gupta_WMM fraction |
| YBX3 | PRR11 | 0.041 | 0.27 | bioplex (PRR11) bioplex_WMM |
| CCNK | SCAF4 | 0.006 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CCNK | YBX3 | 0.005 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CCNK | PRR11 | 0.004 | 0.01 | bioplex (PRR11) |
| CDK12 | YBX3 | 0.004 | 0.01 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_03637 has an average edge precision of 0.2 which is ranked 6173 out of all 6965 complexes.
Related Complexes