hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03648
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RPA2 | Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) | UniProt NCBI |
| RPA3 | Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3) | UniProt NCBI |
| RPA1 | Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed] | UniProt NCBI |
| TFAM | Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2) | UniProt NCBI |
| PARP1 | Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) | UniProt NCBI |
| POLD1 | DNA polymerase delta catalytic subunit (EC 2.7.7.7) (EC 3.1.11.-) (DNA polymerase subunit delta p125) | UniProt NCBI |
| RPAIN | RPA-interacting protein (hRIP) | UniProt NCBI |
| RPA4 | Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1004 | 5.45940618965e-13 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | RC complex during S-phase of cell cycle |
| CORUM:1005 | 5.45940618965e-13 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | RC complex during G2/M-phase of cell cycle |
| KEGG:03430 | 1.47978859642e-11 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | Mismatch repair |
| REAC:R-HSA-110373 | 8.61401377895e-11 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| KEGG:03030 | 1.65428518365e-10 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | DNA replication |
| KEGG:03440 | 2.88547426816e-10 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | Homologous recombination |
| WP:WP466 | 3.9253319813e-10 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | DNA Replication |
| KEGG:03420 | 4.75912137342e-10 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | Nucleotide excision repair |
| REAC:R-HSA-73933 | 5.2544449687e-10 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Resolution of Abasic Sites (AP sites) |
| REAC:R-HSA-5696400 | 1.21174079583e-09 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Dual Incision in GG-NER |
| REAC:R-HSA-174437 | 1.27004442556e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Removal of the Flap Intermediate from the C-strand |
| REAC:R-HSA-174414 | 1.99535506367e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Processive synthesis on the C-strand of the telomere |
| CORUM:5229 | 4.70911134935e-09 | 0.375 | RPA2 RPA3 RPA1 | RPA complex |
| REAC:R-HSA-5358606 | 6.04867413181e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) |
| REAC:R-HSA-5358565 | 6.04867413181e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) |
| REAC:R-HSA-69166 | 6.04867413181e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Removal of the Flap Intermediate |
| REAC:R-HSA-5358508 | 8.24641855088e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Mismatch Repair |
| REAC:R-HSA-69183 | 8.24641855088e-09 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Processive synthesis on the lagging strand |
| GO:0043601 | 2.42915188566e-08 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | nuclear replisome |
| REAC:R-HSA-69186 | 2.92387969037e-08 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Lagging Strand Synthesis |
| REAC:R-HSA-5651801 | 3.61107457747e-08 | 0.5 | RPA2 RPA3 RPA1 POLD1 | PCNA-Dependent Long Patch Base Excision Repair |
| GO:0030894 | 3.68980820905e-08 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | replisome |
| REAC:R-HSA-5696399 | 4.95583477516e-08 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-73884 | 5.92850073883e-08 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Base Excision Repair |
| REAC:R-HSA-174417 | 6.40710506278e-08 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Telomere C-strand (Lagging Strand) Synthesis |
| REAC:R-HSA-5696397 | 7.62586526259e-08 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Gap-filling DNA repair synthesis and ligation in GG-NER |
| CORUM:2222 | 9.41110885571e-08 | 0.375 | RPA2 RPA3 RPA1 | BLM complex II |
| CORUM:2738 | 9.41110885571e-08 | 0.375 | RPA2 RPA3 RPA1 | BLM complex II |
| GO:0006289 | 1.47066608718e-07 | 0.75 | RPA2 POLD1 RPA3 RPA1 PARP1 RPA4 | nucleotide-excision repair |
| REAC:R-HSA-110314 | 1.65029347917e-07 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-180786 | 1.65029347917e-07 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Extension of Telomeres |
| REAC:R-HSA-5656169 | 1.89437369763e-07 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Termination of translesion DNA synthesis |
| REAC:R-HSA-5696398 | 1.95613054198e-07 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Nucleotide Excision Repair |
| GO:0006296 | 1.98894336804e-07 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | nucleotide-excision repair, DNA incision, 5'-to lesion |
| REAC:R-HSA-69190 | 2.16453264205e-07 | 0.5 | RPA2 RPA3 RPA1 POLD1 | DNA strand elongation |
| REAC:R-HSA-68962 | 2.46255883029e-07 | 0.5 | RPA2 RPA4 RPA3 RPA1 | Activation of the pre-replicative complex |
| GO:0033683 | 2.62622334356e-07 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | nucleotide-excision repair, DNA incision |
| GO:0043596 | 3.41710904424e-07 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | nuclear replication fork |
| KEGG:03460 | 3.4455015847e-07 | 0.5 | RPA2 RPA4 RPA3 RPA1 | Fanconi anemia pathway |
| REAC:R-HSA-69306 | 3.89276889356e-07 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | DNA Replication |
| CORUM:248 | 3.94967983144e-07 | 0.375 | RPA2 RPA3 RPA1 | BRAFT complex |
| REAC:R-HSA-110313 | 4.43739625768e-07 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| GO:0006261 | 4.71190498317e-07 | 0.75 | RPA2 RPAIN POLD1 RPA3 RPA1 RPA4 | DNA-dependent DNA replication |
| REAC:R-HSA-5693538 | 5.72743727546e-07 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | Homology Directed Repair |
| REAC:R-HSA-5696395 | 7.41082282042e-07 | 0.5 | RPA2 PARP1 RPA3 RPA1 | Formation of Incision Complex in GG-NER |
| GO:0032993 | 7.48248009588e-07 | 0.75 | RPA2 POLD1 RPA3 RPA1 PARP1 RPA4 | protein-DNA complex |
| CORUM:244 | 7.75439167847e-07 | 0.375 | RPA2 RPA3 RPA1 | BRAFT complex |
| REAC:R-HSA-73893 | 1.07016718079e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | DNA Damage Bypass |
| REAC:R-HSA-5693532 | 1.47228520714e-06 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | DNA Double-Strand Break Repair |
| GO:0005662 | 3.09998667106e-06 | 0.5 | RPA2 RPA4 RPA3 RPA1 | DNA replication factor A complex |
| GO:0005657 | 3.46319417673e-06 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | replication fork |
| REAC:R-HSA-6782210 | 3.79823767099e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Gap-filling DNA repair synthesis and ligation in TC-NER |
| REAC:R-HSA-3371511 | 3.95869190468e-06 | 0.375 | RPA2 RPA3 RPA1 | HSF1 activation |
| REAC:R-HSA-5685942 | 4.04643017452e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | HDR through Homologous Recombination (HRR) |
| REAC:R-HSA-6782135 | 4.04643017452e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Dual incision in TC-NER |
| GO:0090734 | 6.81217565361e-06 | 0.625 | RPA2 PARP1 RPA4 RPA3 RPA1 | site of DNA damage |
| REAC:R-HSA-6781827 | 8.50137867262e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| GO:0006310 | 8.64862247595e-06 | 0.75 | RPA2 RPAIN RPA3 RPA1 PARP1 RPA4 | DNA recombination |
| GO:0006281 | 9.24577430132e-06 | 0.875 | RPA2 RPAIN POLD1 RPA4 RPA1 PARP1 RPA3 | DNA repair |
| GO:0006260 | 9.44318891482e-06 | 0.75 | RPA2 RPAIN POLD1 RPA3 RPA1 RPA4 | DNA replication |
| REAC:R-HSA-157579 | 9.90934286775e-06 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Telomere Maintenance |
| REAC:R-HSA-110312 | 1.00665197731e-05 | 0.375 | RPA2 RPA3 RPA1 | Translesion synthesis by REV1 |
| GO:0006293 | 1.01832303085e-05 | 0.5 | RPA2 PARP1 RPA3 RPA1 | nucleotide-excision repair, preincision complex stabilization |
| GO:0006295 | 1.01832303085e-05 | 0.5 | RPA2 PARP1 RPA3 RPA1 | nucleotide-excision repair, DNA incision, 3'-to lesion |
| REAC:R-HSA-69002 | 1.20493481886e-05 | 0.5 | RPA2 RPA4 RPA3 RPA1 | DNA Replication Pre-Initiation |
| REAC:R-HSA-5655862 | 1.22205513984e-05 | 0.375 | RPA2 RPA3 RPA1 | Translesion synthesis by POLK |
| REAC:R-HSA-5656121 | 1.22205513984e-05 | 0.375 | RPA2 RPA3 RPA1 | Translesion synthesis by POLI |
| GO:0006297 | 1.50599363112e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | nucleotide-excision repair, DNA gap filling |
| REAC:R-HSA-110320 | 1.74055112733e-05 | 0.375 | RPA2 RPA3 RPA1 | Translesion Synthesis by POLH |
| GO:0032201 | 2.98220816207e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | telomere maintenance via semi-conservative replication |
| REAC:R-HSA-73886 | 3.17336382382e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Chromosome Maintenance |
| GO:0006294 | 4.03418526699e-05 | 0.5 | RPA2 PARP1 RPA3 RPA1 | nucleotide-excision repair, preincision complex assembly |
| REAC:R-HSA-73894 | 4.24460256581e-05 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | DNA Repair |
| REAC:R-HSA-69239 | 4.53422061837e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | Synthesis of DNA |
| GO:0006298 | 5.34213382731e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | mismatch repair |
| REAC:R-HSA-69206 | 6.69420878977e-05 | 0.5 | RPA2 RPA4 RPA3 RPA1 | G1/S Transition |
| REAC:R-HSA-5693567 | 6.69420878977e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| GO:0000724 | 9.32372611137e-05 | 0.625 | RPA2 PARP1 RPA4 RPA3 RPA1 | double-strand break repair via homologous recombination |
| GO:0000725 | 9.32372611137e-05 | 0.625 | RPA2 PARP1 RPA4 RPA3 RPA1 | recombinational repair |
| GO:0042769 | 9.99014589936e-05 | 0.5 | RPA2 RPA3 RPA1 POLD1 | DNA damage response, detection of DNA damage |
| REAC:R-HSA-453279 | 0.000109636784979 | 0.5 | RPA2 RPA4 RPA3 RPA1 | Mitotic G1-G1/S phases |
| CORUM:5231 | 0.00011678598518 | 0.25 | RPA2 RPA1 | 53BP1-containing complex |
| REAC:R-HSA-6783310 | 0.00011709032871 | 0.375 | RPA2 RPA3 RPA1 | Fanconi Anemia Pathway |
| GO:0090305 | 0.000118880242109 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | nucleic acid phosphodiester bond hydrolysis |
| GO:0006284 | 0.000125134574466 | 0.5 | RPA2 RPA3 RPA1 POLD1 | base-excision repair |
| REAC:R-HSA-5685938 | 0.000127702698548 | 0.375 | RPA2 RPA3 RPA1 | HDR through Single Strand Annealing (SSA) |
| REAC:R-HSA-176187 | 0.000138935544096 | 0.375 | RPA2 RPA3 RPA1 | Activation of ATR in response to replication stress |
| REAC:R-HSA-69242 | 0.000150143341926 | 0.5 | RPA2 RPA3 RPA1 POLD1 | S Phase |
| REAC:R-HSA-5693616 | 0.000150806270193 | 0.375 | RPA2 RPA3 RPA1 | Presynaptic phase of homologous DNA pairing and strand exchange |
| GO:0019985 | 0.000154861828642 | 0.5 | RPA2 RPA3 RPA1 POLD1 | translesion synthesis |
| GO:0000781 | 0.000180332172518 | 0.625 | RPA2 PARP1 RPA4 RPA1 POLD1 | chromosome, telomeric region |
| REAC:R-HSA-5693579 | 0.000190419512819 | 0.375 | RPA2 RPA3 RPA1 | Homologous DNA Pairing and Strand Exchange |
| WP:WP45 | 0.000201347625851 | 0.375 | RPA2 RPA3 RPA1 | G1 to S cell cycle control |
| GO:0006259 | 0.000210601211554 | 0.875 | RPA2 RPAIN POLD1 RPA4 RPA1 PARP1 RPA3 | DNA metabolic process |
| GO:0006974 | 0.000212679246578 | 0.875 | RPA2 RPAIN POLD1 RPA4 RPA1 PARP1 RPA3 | cellular response to DNA damage stimulus |
| GO:0000723 | 0.000264842319514 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | telomere maintenance |
| GO:0000731 | 0.000276162599924 | 0.5 | RPA2 RPA3 RPA1 POLD1 | DNA synthesis involved in DNA repair |
| GO:0003684 | 0.000358332164808 | 0.5 | RPA2 RPA3 RPA1 POLD1 | damaged DNA binding |
| WP:WP4016 | 0.000384271844534 | 0.375 | RPA2 PARP1 RPA1 | DNA IR-damage and cellular response via ATR |
| GO:0006301 | 0.00038940760077 | 0.5 | RPA2 RPA3 RPA1 POLD1 | postreplication repair |
| GO:0032200 | 0.000402594533896 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | telomere organization |
| REAC:R-HSA-69278 | 0.000445835752854 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | Cell Cycle, Mitotic |
| GO:0033260 | 0.000457563898772 | 0.5 | RPA2 RPA3 RPA1 POLD1 | nuclear DNA replication |
| WP:WP531 | 0.000459085245731 | 0.25 | POLD1 RPA1 | DNA Mismatch Repair |
| WP:WP2446 | 0.000534181644969 | 0.375 | RPA2 RPA3 RPA1 | Retinoblastoma Gene in Cancer |
| GO:0035861 | 0.000576059220125 | 0.5 | RPA2 RPA4 RPA3 PARP1 | site of double-strand break |
| GO:0044786 | 0.000620237823973 | 0.5 | RPA2 RPA3 RPA1 POLD1 | cell cycle DNA replication |
| WP:WP3630 | 0.000701003457493 | 0.25 | TFAM PARP1 | NAD metabolism, sirtuins and aging |
| REAC:R-HSA-3371453 | 0.000775544821205 | 0.375 | RPA2 RPA3 RPA1 | Regulation of HSF1-mediated heat shock response |
| WP:WP186 | 0.000840978166984 | 0.25 | POLD1 RPA1 | Homologous recombination |
| CORUM:1098 | 0.000908974898571 | 0.25 | POLD1 RPA1 | DNA synthesome complex (13 subunits) |
| REAC:R-HSA-1640170 | 0.00108292913925 | 0.625 | RPA2 RPA4 RPA3 RPA1 POLD1 | Cell Cycle |
| CORUM:1099 | 0.00158317684197 | 0.25 | POLD1 RPA1 | DNA synthesome complex (17 subunits) |
| CORUM:1111 | 0.00158317684197 | 0.25 | POLD1 RPA1 | DNA synthesome complex (17 subunits) |
| REAC:R-HSA-912446 | 0.00174484118312 | 0.375 | RPA2 RPA3 RPA1 | Meiotic recombination |
| REAC:R-HSA-3371556 | 0.00174484118312 | 0.375 | RPA2 RPA3 RPA1 | Cellular response to heat stress |
| GO:0006283 | 0.00183129501431 | 0.5 | RPA2 RPA3 RPA1 POLD1 | transcription-coupled nucleotide-excision repair |
| REAC:R-HSA-6804756 | 0.0021428667452 | 0.375 | RPA2 RPA3 RPA1 | Regulation of TP53 Activity through Phosphorylation |
| GO:0006302 | 0.00221843806518 | 0.625 | RPA2 PARP1 RPA4 RPA3 RPA1 | double-strand break repair |
| REAC:R-HSA-69473 | 0.00236260250697 | 0.375 | RPA2 RPA3 RPA1 | G2/M DNA damage checkpoint |
| REAC:R-HSA-5693607 | 0.00259674522301 | 0.375 | RPA2 RPA3 RPA1 | Processing of DNA double-strand break ends |
| REAC:R-HSA-1500620 | 0.00421694153061 | 0.375 | RPA2 RPA3 RPA1 | Meiosis |
| GO:0003697 | 0.00533098594204 | 0.5 | RPA2 RPA4 RPA3 RPA1 | single-stranded DNA binding |
| GO:0098687 | 0.00533981403346 | 0.625 | RPA2 PARP1 RPA4 RPA1 POLD1 | chromosomal region |
| GO:0042276 | 0.00577307926818 | 0.375 | RPA2 RPA3 RPA1 | error-prone translesion synthesis |
| GO:0070987 | 0.00577307926818 | 0.375 | RPA2 RPA3 RPA1 | error-free translesion synthesis |
| REAC:R-HSA-1474165 | 0.00582709935665 | 0.375 | RPA2 RPA3 RPA1 | Reproduction |
| KEGG:03410 | 0.00597189217143 | 0.25 | POLD1 PARP1 | Base excision repair |
| GO:0060249 | 0.00627777582342 | 0.625 | RPA2 PARP1 RPA3 RPA1 POLD1 | anatomical structure homeostasis |
| REAC:R-HSA-5633007 | 0.0109755382127 | 0.375 | RPA2 RPA3 RPA1 | Regulation of TP53 Activity |
| GO:0003677 | 0.01150474629 | 0.875 | RPA2 POLD1 RPA1 RPA4 PARP1 TFAM RPA3 | DNA binding |
| GO:0000784 | 0.0127865021438 | 0.5 | RPA2 PARP1 RPA1 POLD1 | nuclear chromosome, telomeric region |
| REAC:R-HSA-69481 | 0.0131910130095 | 0.375 | RPA2 RPA3 RPA1 | G2/M Checkpoints |
| HPA:050020_12 | 0.0187713783843 | 0.5 | TFAM RPA2 PARP1 RPA1 | spleen; cells in white pulp[Supported,Medium] |
| HPA:007020_12 | 0.0247188185218 | 0.5 | TFAM RPA2 PARP1 RPA1 | cerebellum; cells in granular layer[Supported,Medium] |
| GO:0071897 | 0.0276791086381 | 0.5 | RPA2 RPA3 RPA1 POLD1 | DNA biosynthetic process |
| HPA:007030_12 | 0.0321408085258 | 0.5 | TFAM RPA2 PARP1 RPA1 | cerebellum; cells in molecular layer[Supported,Medium] |
| HPA:050020_13 | 0.0326910458311 | 0.375 | RPA2 PARP1 RPA1 | spleen; cells in white pulp[Supported,High] |
| HPA:043010_12 | 0.0335542438191 | 0.5 | TFAM RPA2 PARP1 RPA1 | skin 1; Langerhans[Supported,Medium] |
| HPA:028010_12 | 0.0339662958962 | 0.5 | TFAM RPA2 PARP1 RPA1 | lymph node; germinal center cells[Supported,Medium] |
| GO:0051606 | 0.0362947680097 | 0.5 | RPA2 RPA3 RPA1 POLD1 | detection of stimulus |
| REAC:R-HSA-74160 | 0.037866398773 | 0.625 | TFAM RPA2 PARP1 RPA3 RPA1 | Gene expression (Transcription) |
| HPA:021010_12 | 0.0380676236285 | 0.5 | TFAM RPA2 PARP1 RPA1 | heart muscle; myocytes[Supported,Medium] |
| HPA:009020_12 | 0.0392044529587 | 0.5 | TFAM RPA2 PARP1 RPA1 | cervix, uterine; squamous epithelial cells[Supported,Medium] |
| HPA:022020_12 | 0.0403658824352 | 0.5 | TFAM RPA2 PARP1 RPA1 | hippocampus; neuronal cells[Supported,Medium] |
| HPA:004030_12 | 0.0420338357117 | 0.5 | TFAM RPA2 PARP1 RPA1 | breast; myoepithelial cells[Supported,Medium] |
| HPA:033010_12 | 0.0422761557901 | 0.5 | TFAM RPA2 PARP1 RPA1 | parathyroid gland; glandular cells[Supported,Medium] |
| HPA:043040_12 | 0.0437515506565 | 0.5 | TFAM RPA2 PARP1 RPA1 | skin 1; melanocytes[Supported,Medium] |
| HPA:007010_12 | 0.0452641727451 | 0.5 | TFAM RPA2 PARP1 RPA1 | cerebellum; Purkinje cells[Supported,Medium] |
| HPA:048030_11 | 0.0481359125497 | 0.5 | TFAM RPA2 PARP1 RPA1 | soft tissue 2; fibroblasts[Supported,Low] |
| HPA:028020_12 | 0.0492123809871 | 0.5 | TFAM RPA2 PARP1 RPA1 | lymph node; non-germinal center cells[Supported,Medium] |
| CORUM:7352 | 0.0497224828424 | 0.125 | PARP1 | PARP1-LIG3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPA2 | RPA1 | 1.0 | 0.949 | hein_WMM bioplex (RPA2) bioplex_WMM Guru boldt youn_WMM hein (RPA1) Malo gupta_WMM fraction boldt_WMM |
| RPA3 | RPA1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (RPA1) Malo gupta_WMM fraction boldt_WMM |
| RPA2 | RPA3 | 1.0 | 0.949 | hein_WMM bioplex (RPA2) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| RPA2 | RPAIN | 0.304 | 0.499 | bioplex (RPA2,RPAIN) bioplex_WMM |
| RPA3 | POLD1 | 0.263 | 0.482 | youn_WMM gupta_WMM fraction |
| PARP1 | RPA2 | 0.165 | 0.42 | bioplex (RPA2) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| RPA3 | RPA4 | 0.128 | 0.399 | bioplex (RPA4) bioplex_WMM |
| PARP1 | RPA1 | 0.104 | 0.368 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RPA1 | RPA4 | 0.1 | 0.361 | bioplex (RPA4) bioplex_WMM |
| PARP1 | RPA3 | 0.1 | 0.36 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| RPA3 | RPAIN | 0.041 | 0.27 | bioplex (RPAIN) bioplex_WMM |
| RPA1 | RPAIN | 0.034 | 0.257 | bioplex (RPAIN) bioplex_WMM |
| TFAM | RPA1 | 0.022 | 0.211 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| POLD1 | RPA1 | 0.007 | 0.01 | youn_WMM gupta_WMM WMM_only |
| RPA2 | POLD1 | 0.007 | 0.008 | bioplex_WMM youn_WMM WMM_only |
| TFAM | RPA3 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PARP1 | POLD1 | 0.007 | 0.004 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TFAM | PARP1 | 0.007 | 0.003 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TFAM | POLD1 | 0.007 | 0.0 | bioplex_WMM boldt youn_WMM boldt_WMM |
| RPA2 | RPA4 | 0.006 | 0.004 | bioplex (RPA4) bioplex_WMM |
| TFAM | RPA2 | 0.005 | 0.011 | bioplex (RPA2) bioplex_WMM |
| PARP1 | RPA4 | 0.005 | 0.013 | bioplex (RPA4) bioplex_WMM |
| PARP1 | RPAIN | 0.0 | 0.017 | bioplex (RPAIN) bioplex_WMM |
Images
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Complex HuMAP2_03648 has an average edge precision of 0.285 which is ranked 4815 out of all 6965 complexes.
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