hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03664
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| OSBPL5 | Oxysterol-binding protein-related protein 5 (ORP-5) (OSBP-related protein 5) (Oxysterol-binding protein homolog 1) | UniProt NCBI |
| OSBPL8 | Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) | UniProt NCBI |
| NAGLU | Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] | UniProt NCBI |
| PRR11 | Proline-rich protein 11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1482801 | 0.000914071346391 | 0.5 | OSBPL5 OSBPL8 | Acyl chain remodelling of PS |
| GO:0140343 | 0.00270494046827 | 0.5 | OSBPL5 OSBPL8 | phosphatidylserine transfer activity |
| REAC:R-HSA-2206282 | 0.0499190562503 | 0.25 | NAGLU | MPS IIIB - Sanfilippo syndrome B |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| OSBPL5 | OSBPL8 | 0.444 | 0.587 | bioplex (OSBPL5) bioplex_WMM |
| PRR11 | OSBPL5 | 0.166 | 0.422 | bioplex (OSBPL5) bioplex_WMM |
| OSBPL5 | NAGLU | 0.034 | 0.261 | bioplex (OSBPL5) bioplex_WMM |
| PRR11 | NAGLU | 0.007 | 0.002 | bioplex_WMM WMM_only |
| OSBPL8 | NAGLU | 0.006 | 0.003 | bioplex_WMM WMM_only |
| PRR11 | OSBPL8 | 0.0 | 0.001 | bioplex (PRR11) bioplex_WMM |
Images
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Complex HuMAP2_03664 has an average edge precision of 0.213 which is ranked 5983 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| OSBPL5 | HuMAP2_03664 HuMAP2_04219 HuMAP2_04943 |
| OSBPL8 | HuMAP2_03664 HuMAP2_04943 |
| NAGLU | HuMAP2_03664 |
| PRR11 | HuMAP2_03637 HuMAP2_03664 HuMAP2_04219 HuMAP2_04943 |