hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03670
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZC3H15 | Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4) | UniProt NCBI |
| NTMT1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (N-terminal RCC1 methyltransferase) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A) [Cleaved into: N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed] | UniProt NCBI |
| ETF1 | Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1) | UniProt NCBI |
| LRRC41 | Leucine-rich repeat-containing protein 41 (Protein Muf1) | UniProt NCBI |
| DRG1 | Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) | UniProt NCBI |
| POLA1 | DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:809 | 0.0499726005494 | 0.166666666667 | ETF1 | eRF1-eRF3-GTP-Mg(2+) complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DRG1 | ZC3H15 | 0.999 | 0.949 | bioplex (DRG1) bioplex_WMM Guru boldt youn_WMM fraction boldt_WMM |
| DRG1 | LRRC41 | 0.941 | 0.853 | bioplex (DRG1) bioplex_WMM youn_WMM |
| DRG1 | ETF1 | 0.127 | 0.4 | youn (ETF1) bioplex_WMM youn_WMM fraction treiber_WMM |
| ZC3H15 | ETF1 | 0.092 | 0.355 | youn (ETF1) youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| POLA1 | DRG1 | 0.049 | 0.293 | bioplex_WMM Guru youn_WMM fraction |
| DRG1 | NTMT1 | 0.048 | 0.295 | bioplex (DRG1) bioplex_WMM youn_WMM |
| POLA1 | ZC3H15 | 0.018 | 0.177 | youn_WMM gupta_WMM fraction boldt_WMM |
| POLA1 | ETF1 | 0.018 | 0.178 | youn (ETF1) youn_WMM gupta_WMM fraction boldt_WMM bioplex_WMM |
| ZC3H15 | NTMT1 | 0.009 | 0.099 | bioplex_WMM gupta_WMM WMM_only |
| ZC3H15 | LRRC41 | 0.008 | 0.089 | bioplex_WMM youn_WMM WMM_only |
| LRRC41 | NTMT1 | 0.008 | 0.023 | bioplex_WMM youn_WMM WMM_only |
| ETF1 | NTMT1 | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
| POLA1 | LRRC41 | 0.007 | 0.0 | youn_WMM WMM_only bioplex_WMM |
| LRRC41 | ETF1 | 0.007 | 0.004 | youn (ETF1) youn_WMM |
Images
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Complex HuMAP2_03670 has an average edge precision of 0.266 which is ranked 5113 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZC3H15 | HuMAP2_01111 HuMAP2_02469 HuMAP2_03670 HuMAP2_05596 |
| NTMT1 | HuMAP2_03670 |
| ETF1 | HuMAP2_03606 HuMAP2_03670 HuMAP2_04153 HuMAP2_06250 HuMAP2_06475 |
| LRRC41 | HuMAP2_01111 HuMAP2_02469 HuMAP2_03670 |
| DRG1 | HuMAP2_01111 HuMAP2_02469 HuMAP2_03670 HuMAP2_05596 |
| POLA1 | HuMAP2_00663 HuMAP2_01177 HuMAP2_01225 HuMAP2_03670 HuMAP2_04366 HuMAP2_06629 |