hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03675
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NSMCE1 | Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27) | UniProt NCBI |
| SMC6 | Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (hSMC6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3108214 | 0.004164669804 | 1.0 | NSMCE1 SMC6 | SUMOylation of DNA damage response and repair proteins |
| GO:0030915 | 0.00946729163895 | 1.0 | NSMCE1 SMC6 | Smc5-Smc6 complex |
| GO:0106068 | 0.00946729163895 | 1.0 | NSMCE1 SMC6 | SUMO ligase complex |
| REAC:R-HSA-3108232 | 0.0229517718172 | 1.0 | NSMCE1 SMC6 | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.0246461304377 | 1.0 | NSMCE1 SMC6 | SUMOylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMC6 | NSMCE1 | 1.0 | 0.949 | hein_WMM bioplex (NSMCE1) bioplex_WMM hein (SMC6) Malo fraction |
Images
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Complex HuMAP2_03675 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NSMCE1 | HuMAP2_00383 HuMAP2_00828 HuMAP2_03675 HuMAP2_04865 HuMAP2_05208 HuMAP2_06156 |
| SMC6 | HuMAP2_00383 HuMAP2_00828 HuMAP2_01653 HuMAP2_03675 HuMAP2_04865 HuMAP2_05208 |