hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03680
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOB1 | RNA-binding protein NOB1 (Phosphorylation regulatory protein HP-10) (Protein ART-4) | UniProt NCBI |
| FGFRL1 | Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (FGF homologous factor receptor) (FGFR-like protein) (Fibroblast growth factor receptor 5) (FGFR-5) | UniProt NCBI |
| HLA-DPA1 | HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1) | UniProt NCBI |
| HS3ST3B1 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B) | UniProt NCBI |
| B4GALT4 | Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Lactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4) | UniProt NCBI |
| ATP13A2 | Cation-transporting ATPase 13A2 (EC 3.6.3.-) | UniProt NCBI |
| HBA1 | Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) | UniProt NCBI |
| DCBLD1 | Discoidin, CUB and LCCL domain-containing protein 1 | UniProt NCBI |
| CHST11 | Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) | UniProt NCBI |
| APOE | Apolipoprotein E (Apo-E) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1630316 | 0.00652483358031 | 0.333333333333 | CHST11 B4GALT4 HS3ST3B1 | Glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NOB1 | HLA-DPA1 | 0.242 | 0.468 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | ATP13A2 | 0.201 | 0.45 | bioplex (HLA-DPA1) bioplex_WMM |
| FGFRL1 | HLA-DPA1 | 0.069 | 0.349 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | HBA1 | 0.068 | 0.348 | bioplex (HLA-DPA1) bioplex_WMM |
| APOE | HLA-DPA1 | 0.051 | 0.299 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | B4GALT4 | 0.035 | 0.261 | bioplex (HLA-DPA1) bioplex_WMM |
| DCBLD1 | HLA-DPA1 | 0.031 | 0.239 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | HS3ST3B1 | 0.027 | 0.225 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | CHST11 | 0.021 | 0.188 | bioplex (HLA-DPA1) bioplex_WMM |
| DCBLD1 | FGFRL1 | 0.009 | 0.11 | bioplex_WMM WMM_only |
| DCBLD1 | HS3ST3B1 | 0.009 | 0.102 | bioplex_WMM WMM_only |
| CHST11 | HS3ST3B1 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| B4GALT4 | HS3ST3B1 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| FGFRL1 | HS3ST3B1 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| DCBLD1 | CHST11 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| APOE | HS3ST3B1 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| NOB1 | HS3ST3B1 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| DCBLD1 | B4GALT4 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| ATP13A2 | HS3ST3B1 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| B4GALT4 | CHST11 | 0.008 | 0.068 | bioplex_WMM WMM_only |
| FGFRL1 | CHST11 | 0.008 | 0.069 | bioplex_WMM WMM_only |
| DCBLD1 | APOE | 0.008 | 0.066 | bioplex_WMM WMM_only |
| DCBLD1 | NOB1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| APOE | CHST11 | 0.008 | 0.049 | bioplex_WMM WMM_only |
| NOB1 | CHST11 | 0.008 | 0.035 | bioplex_WMM WMM_only |
| DCBLD1 | HBA1 | 0.008 | 0.029 | bioplex_WMM WMM_only |
| DCBLD1 | ATP13A2 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| FGFRL1 | B4GALT4 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| HBA1 | HS3ST3B1 | 0.008 | 0.015 | bioplex_WMM WMM_only |
| ATP13A2 | CHST11 | 0.008 | 0.013 | bioplex_WMM WMM_only |
| APOE | B4GALT4 | 0.008 | 0.015 | bioplex_WMM WMM_only |
| APOE | FGFRL1 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| NOB1 | B4GALT4 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| FGFRL1 | NOB1 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| APOE | NOB1 | 0.007 | 0.018 | bioplex_WMM WMM_only |
| B4GALT4 | ATP13A2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| FGFRL1 | ATP13A2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| HBA1 | CHST11 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| APOE | ATP13A2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| NOB1 | ATP13A2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| FGFRL1 | HBA1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| B4GALT4 | HBA1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| APOE | HBA1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| NOB1 | HBA1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| ATP13A2 | HBA1 | 0.006 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03680 has an average edge precision of 0.096 which is ranked 6942 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NOB1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_03680 HuMAP2_05710 HuMAP2_06629 HuMAP2_06766 |
| FGFRL1 | HuMAP2_02078 HuMAP2_03680 |
| HLA-DPA1 | HuMAP2_03680 HuMAP2_05710 |
| HS3ST3B1 | HuMAP2_03680 |
| B4GALT4 | HuMAP2_03680 |
| ATP13A2 | HuMAP2_03680 HuMAP2_05710 |
| HBA1 | HuMAP2_03680 HuMAP2_04634 HuMAP2_06091 |
| DCBLD1 | HuMAP2_00580 HuMAP2_03680 HuMAP2_06092 |
| CHST11 | HuMAP2_03680 |
| APOE | HuMAP2_01915 HuMAP2_02283 HuMAP2_03680 HuMAP2_05710 |