hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03688
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GSDMA | Gasdermin-A (Gasdermin-1) | UniProt NCBI |
| S100A16 | Protein S100-A16 (Aging-associated gene 13 protein) (Protein S100-F) (S100 calcium-binding protein A16) | UniProt NCBI |
| TGM1 | Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) | UniProt NCBI |
| S100A14 | Protein S100-A14 (S100 calcium-binding protein A14) (S114) | UniProt NCBI |
| NCCRP1 | F-box only protein 50 (NCC receptor protein 1 homolog) (NCCRP-1) (Non-specific cytotoxic cell receptor protein 1 homolog) | UniProt NCBI |
| POF1B | Protein POF1B (Premature ovarian failure protein 1B) | UniProt NCBI |
| ARG1 | Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) | UniProt NCBI |
| CASP14 | Caspase-14 (CASP-14) (EC 3.4.22.-) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form] | UniProt NCBI |
| ALOX12B | Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) | UniProt NCBI |
| ECM1 | Extracellular matrix protein 1 (Secretory component p85) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011124 | 0.00453424357214 | 0.3 | TGM1 ALOX12B CASP14 | Abnormality of epidermal morphology |
| HP:0007479 | 0.0228430052933 | 0.2 | TGM1 ALOX12B | Congenital nonbullous ichthyosiform erythroderma |
| WP:WP2840 | 0.0453793070633 | 0.2 | GSDMA CASP14 | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| S100A14 | TGM1 | 0.139 | 0.406 | bioplex_WMM boldt boldt_WMM |
| ALOX12B | TGM1 | 0.092 | 0.355 | bioplex_WMM boldt boldt_WMM |
| NCCRP1 | TGM1 | 0.066 | 0.349 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| NCCRP1 | ECM1 | 0.038 | 0.265 | bioplex_WMM boldt boldt_WMM |
| ALOX12B | NCCRP1 | 0.036 | 0.264 | bioplex_WMM boldt boldt_WMM |
| TGM1 | GSDMA | 0.035 | 0.263 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| NCCRP1 | S100A14 | 0.034 | 0.257 | bioplex_WMM boldt boldt_WMM |
| S100A14 | ARG1 | 0.032 | 0.244 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ALOX12B | ECM1 | 0.029 | 0.233 | bioplex_WMM boldt boldt_WMM |
| NCCRP1 | POF1B | 0.025 | 0.212 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| S100A14 | POF1B | 0.023 | 0.209 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| TGM1 | S100A16 | 0.021 | 0.191 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| TGM1 | CASP14 | 0.021 | 0.188 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ECM1 | ARG1 | 0.021 | 0.187 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ALOX12B | S100A14 | 0.02 | 0.189 | bioplex_WMM boldt boldt_WMM |
| NCCRP1 | CASP14 | 0.019 | 0.184 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ECM1 | TGM1 | 0.019 | 0.183 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| TGM1 | POF1B | 0.018 | 0.182 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ECM1 | S100A14 | 0.018 | 0.18 | bioplex_WMM boldt boldt_WMM |
| TGM1 | ARG1 | 0.017 | 0.174 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| NCCRP1 | ARG1 | 0.016 | 0.161 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ALOX12B | GSDMA | 0.016 | 0.154 | bioplex_WMM WMM_only boldt_WMM |
| ECM1 | POF1B | 0.015 | 0.143 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| NCCRP1 | GSDMA | 0.015 | 0.14 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| ARG1 | CASP14 | 0.015 | 0.14 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ALOX12B | ARG1 | 0.015 | 0.14 | bioplex_WMM boldt boldt_WMM |
| ALOX12B | POF1B | 0.013 | 0.153 | bioplex_WMM boldt boldt_WMM |
| S100A14 | CASP14 | 0.013 | 0.155 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| S100A14 | GSDMA | 0.013 | 0.15 | bioplex_WMM WMM_only boldt_WMM |
| GSDMA | CASP14 | 0.012 | 0.149 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| ALOX12B | CASP14 | 0.012 | 0.147 | bioplex_WMM boldt boldt_WMM |
| ECM1 | CASP14 | 0.011 | 0.14 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ECM1 | GSDMA | 0.011 | 0.133 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| S100A14 | S100A16 | 0.011 | 0.142 | bioplex_WMM boldt boldt_WMM |
| GSDMA | ARG1 | 0.01 | 0.121 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| POF1B | S100A16 | 0.01 | 0.12 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ECM1 | S100A16 | 0.01 | 0.103 | bioplex_WMM boldt boldt_WMM |
| POF1B | ARG1 | 0.009 | 0.114 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| POF1B | GSDMA | 0.009 | 0.115 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| ALOX12B | S100A16 | 0.009 | 0.104 | bioplex_WMM boldt boldt_WMM |
| NCCRP1 | S100A16 | 0.008 | 0.041 | bioplex_WMM boldt boldt_WMM |
| POF1B | CASP14 | 0.008 | 0.033 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| ARG1 | S100A16 | 0.005 | 0.007 | bioplex_WMM boldt boldt_WMM |
| CASP14 | S100A16 | 0.004 | 0.015 | bioplex_WMM boldt boldt_WMM |
| GSDMA | S100A16 | 0.004 | 0.013 | bioplex_WMM WMM_only boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_03688 has an average edge precision of 0.168 which is ranked 6550 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GSDMA | HuMAP2_03688 HuMAP2_06378 |
| S100A16 | HuMAP2_03688 |
| TGM1 | HuMAP2_03003 HuMAP2_03688 HuMAP2_05854 |
| S100A14 | HuMAP2_03003 HuMAP2_03688 HuMAP2_05854 |
| NCCRP1 | HuMAP2_02794 HuMAP2_03003 HuMAP2_03688 HuMAP2_05854 |
| POF1B | HuMAP2_03688 |
| ARG1 | HuMAP2_03688 |
| CASP14 | HuMAP2_03688 |
| ALOX12B | HuMAP2_02794 HuMAP2_03003 HuMAP2_03688 HuMAP2_05322 |
| ECM1 | HuMAP2_02794 HuMAP2_03688 |