hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03694
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPME1 | Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) | UniProt NCBI |
| PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5876 | 1.67592346237e-05 | 1.0 | PPP2CA PPME1 | PPP2R1A-PPP2R1B-PPP2CA-PPME1-EIF4A1 complex |
| REAC:R-HSA-69273 | 0.000502777038712 | 1.0 | PPP2CA PPME1 | Cyclin A/B1/B2 associated events during G2/M transition |
| REAC:R-HSA-69275 | 0.0300912057669 | 1.0 | PPP2CA PPME1 | G2/M Transition |
| REAC:R-HSA-453274 | 0.0307297326061 | 1.0 | PPP2CA PPME1 | Mitotic G2-G2/M phases |
| CORUM:1543 | 0.0499173803268 | 0.5 | PPP2CA | PPP2CA-PPP2R1A complex |
| CORUM:6111 | 0.0499173803268 | 0.5 | PPP2CA | protein phosphatase 2A C-subunit-synapsin complex |
| CORUM:6159 | 0.0499173803268 | 0.5 | PPP2CA | LPP-PPP2CA-PPP2R3A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP2CA | PPME1 | 0.723 | 0.733 | hein_WMM bioplex (PPME1) bioplex_WMM gupta_WMM |
Images
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Complex HuMAP2_03694 has an average edge precision of 0.733 which is ranked 1248 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPME1 | HuMAP2_02007 HuMAP2_03694 |
| PPP2CA | HuMAP2_02007 HuMAP2_03694 HuMAP2_04458 HuMAP2_05962 |