hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03705
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIKESHI | Protein Hikeshi | UniProt NCBI |
| PGAM1 | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) | UniProt NCBI |
| PGAM4 | Probable phosphoglycerate mutase 4 (EC 5.4.2.11) (EC 5.4.2.4) | UniProt NCBI |
| PGAM2 | Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M) | UniProt NCBI |
| CCDC58 | Coiled-coil domain-containing protein 58 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004619 | 9.08185760231e-07 | 0.6 | PGAM4 PGAM1 PGAM2 | phosphoglycerate mutase activity |
| KEGG:00260 | 7.87603768796e-06 | 0.6 | PGAM4 PGAM1 PGAM2 | Glycine, serine and threonine metabolism |
| KEGG:00010 | 3.41403204501e-05 | 0.6 | PGAM4 PGAM1 PGAM2 | Glycolysis / Gluconeogenesis |
| KEGG:05230 | 4.11682217947e-05 | 0.6 | PGAM4 PGAM1 PGAM2 | Central carbon metabolism in cancer |
| KEGG:01230 | 4.90975651011e-05 | 0.6 | PGAM4 PGAM1 PGAM2 | Biosynthesis of amino acids |
| GO:0016868 | 0.000108905457596 | 0.6 | PGAM4 PGAM1 PGAM2 | intramolecular transferase activity, phosphotransferases |
| KEGG:04922 | 0.000122427590077 | 0.6 | PGAM4 PGAM1 PGAM2 | Glucagon signaling pathway |
| KEGG:01200 | 0.000205667969449 | 0.6 | PGAM4 PGAM1 PGAM2 | Carbon metabolism |
| GO:0016866 | 0.00160515829483 | 0.6 | PGAM4 PGAM1 PGAM2 | intramolecular transferase activity |
| WP:WP534 | 0.00314132080553 | 0.4 | PGAM2 PGAM1 | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00584945327803 | 0.4 | PGAM2 PGAM1 | Gluconeogenesis |
| MIRNA:hsa-miR-3907 | 0.0182219199199 | 0.4 | PGAM4 PGAM1 | hsa-miR-3907 |
| MIRNA:hsa-miR-6772-3p | 0.0270575118475 | 0.4 | PGAM4 PGAM1 | hsa-miR-6772-3p |
| REAC:R-HSA-70171 | 0.0287045163353 | 0.4 | PGAM2 PGAM1 | Glycolysis |
| MIRNA:hsa-miR-7112-5p | 0.0295366697088 | 0.4 | PGAM4 PGAM1 | hsa-miR-7112-5p |
| MIRNA:hsa-miR-4697-3p | 0.0321237558472 | 0.4 | PGAM4 PGAM1 | hsa-miR-4697-3p |
| MIRNA:hsa-miR-6733-3p | 0.0420272255805 | 0.4 | PGAM4 PGAM1 | hsa-miR-6733-3p |
| REAC:R-HSA-70326 | 0.0443461879505 | 0.4 | PGAM2 PGAM1 | Glucose metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PGAM4 | PGAM2 | 1.0 | 0.949 | bioplex (PGAM2) bioplex_WMM |
| PGAM1 | PGAM2 | 0.424 | 0.574 | bioplex (PGAM2) bioplex_WMM youn_WMM |
| PGAM1 | CCDC58 | 0.039 | 0.264 | bioplex_WMM fraction |
| PGAM1 | HIKESHI | 0.021 | 0.191 | bioplex (HIKESHI) fraction |
| PGAM1 | PGAM4 | 0.009 | 0.109 | bioplex_WMM youn_WMM WMM_only |
| CCDC58 | HIKESHI | 0.006 | 0.006 | fraction |
| PGAM2 | HIKESHI | 0.006 | 0.004 | fraction |
| PGAM2 | CCDC58 | 0.0 | 0.008 | fraction |
Images
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Complex HuMAP2_03705 has an average edge precision of 0.263 which is ranked 5166 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HIKESHI | HuMAP2_01649 HuMAP2_02386 HuMAP2_03705 HuMAP2_04603 |
| PGAM1 | HuMAP2_00164 HuMAP2_03705 |
| PGAM4 | HuMAP2_00164 HuMAP2_01140 HuMAP2_03705 |
| PGAM2 | HuMAP2_00164 HuMAP2_01140 HuMAP2_03705 |
| CCDC58 | HuMAP2_00546 HuMAP2_01331 HuMAP2_03705 |