hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03721
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBMX | RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed] | UniProt NCBI |
| HNRNPL | Heterogeneous nuclear ribonucleoprotein L (hnRNP L) | UniProt NCBI |
| HNRNPK | Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP) | UniProt NCBI |
| LDHB | L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP411 | 7.12553605747e-05 | 0.75 | RBMX HNRNPK HNRNPL | mRNA Processing |
| HPA:031010_13 | 0.000633779950094 | 0.75 | RBMX HNRNPK HNRNPL | ovary; follicle cells[Supported,High] |
| HPA:013010_13 | 0.00093798189622 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 1; cells in endometrial stroma[Supported,High] |
| REAC:R-HSA-72163 | 0.0012370641562 | 0.75 | RBMX HNRNPK HNRNPL | mRNA Splicing - Major Pathway |
| CORUM:5615 | 0.00126963544416 | 0.5 | HNRNPL HNRNPK | Emerin complex 52 |
| REAC:R-HSA-72172 | 0.00141192686346 | 0.75 | RBMX HNRNPK HNRNPL | mRNA Splicing |
| HPA:011010_13 | 0.00193884544916 | 0.75 | RBMX HNRNPK HNRNPL | colon; endothelial cells[Supported,High] |
| HPA:011030_13 | 0.00204712562431 | 0.75 | RBMX HNRNPK HNRNPL | colon; peripheral nerve/ganglion[Supported,High] |
| HPA:013010_03 | 0.00210273983896 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 1; cells in endometrial stroma[Uncertain,High] |
| HPA:041010_13 | 0.00264905188628 | 0.75 | RBMX HNRNPK HNRNPL | skeletal muscle; myocytes[Supported,High] |
| HPA:031010_03 | 0.00264905188628 | 0.75 | RBMX HNRNPK HNRNPL | ovary; follicle cells[Uncertain,High] |
| REAC:R-HSA-72203 | 0.00285014014969 | 0.75 | RBMX HNRNPK HNRNPL | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:024010_13 | 0.0031703873793 | 0.75 | RBMX HNRNPK HNRNPL | kidney; cells in glomeruli[Supported,High] |
| HPA:047020_12 | 0.00347435083739 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; chondrocytes[Supported,Medium] |
| HPA:007020_13 | 0.0038387390066 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in granular layer[Supported,High] |
| HPA:043040_13 | 0.00405171426946 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; melanocytes[Supported,High] |
| HPA:043030_13 | 0.00427238602698 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; keratinocytes[Supported,High] |
| HPA:027020_13 | 0.00473735436563 | 0.75 | RBMX HNRNPK HNRNPL | lung; pneumocytes[Supported,High] |
| HPA:006020_13 | 0.00503181450466 | 0.75 | RBMX HNRNPK HNRNPL | caudate; neuronal cells[Supported,High] |
| HPA:047040_12 | 0.00544296527066 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; peripheral nerve[Supported,Medium] |
| HPA:009020_13 | 0.00582049252778 | 0.75 | RBMX HNRNPK HNRNPL | cervix, uterine; squamous epithelial cells[Supported,High] |
| HPA:014020_13 | 0.00593145808864 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 2; glandular cells[Supported,High] |
| HPA:022020_13 | 0.00610052218759 | 0.75 | RBMX HNRNPK HNRNPL | hippocampus; neuronal cells[Supported,High] |
| HPA:058010_13 | 0.00644817227818 | 0.75 | RBMX HNRNPK HNRNPL | vagina; squamous epithelial cells[Supported,High] |
| HPA:007030_13 | 0.0066268155894 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in molecular layer[Supported,High] |
| HPA:056010_13 | 0.00674771511883 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; germinal center cells[Supported,High] |
| HPA:011030_03 | 0.00718236211525 | 0.75 | RBMX HNRNPK HNRNPL | colon; peripheral nerve/ganglion[Uncertain,High] |
| HPA:056020_13 | 0.00718236211525 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; non-germinal center cells[Supported,High] |
| HPA:007010_13 | 0.00718236211525 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; Purkinje cells[Supported,High] |
| HPA:009010_13 | 0.00743886355825 | 0.75 | RBMX HNRNPK HNRNPL | cervix, uterine; glandular cells[Supported,High] |
| HPA:013020_13 | 0.00770136360784 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 1; glandular cells[Supported,High] |
| HPA:048040_12 | 0.00770136360784 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 2; peripheral nerve[Supported,Medium] |
| HPA:047020_11 | 0.00783488424581 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; chondrocytes[Supported,Low] |
| HPA:031010_12 | 0.00831427131638 | 0.75 | RBMX HNRNPK HNRNPL | ovary; follicle cells[Supported,Medium] |
| HPA:053010_13 | 0.00859673358264 | 0.75 | RBMX HNRNPK HNRNPL | testis; Leydig cells[Supported,High] |
| HPA:056030_13 | 0.00918058234339 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; squamous epithelial cells[Supported,High] |
| HPA:024010_03 | 0.00940611765369 | 0.75 | RBMX HNRNPK HNRNPL | kidney; cells in glomeruli[Uncertain,High] |
| HPA:039010_13 | 0.0101046758484 | 0.75 | RBMX HNRNPK HNRNPL | salivary gland; glandular cells[Supported,High] |
| HPA:011010_03 | 0.0101843487884 | 0.75 | RBMX HNRNPK HNRNPL | colon; endothelial cells[Uncertain,High] |
| HPA:027020_03 | 0.0106711364101 | 0.75 | RBMX HNRNPK HNRNPL | lung; pneumocytes[Uncertain,High] |
| HPA:007020_03 | 0.0109202023524 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in granular layer[Uncertain,High] |
| HPA:043030_03 | 0.0115162571215 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; keratinocytes[Uncertain,High] |
| HPA:026010_12 | 0.011690427788 | 0.75 | RBMX HNRNPK HNRNPL | liver; bile duct cells[Supported,Medium] |
| HPA:004010_12 | 0.0117781632296 | 0.75 | RBMX HNRNPK HNRNPL | breast; adipocytes[Supported,Medium] |
| HPA:041010_03 | 0.0122233832836 | 0.75 | RBMX HNRNPK HNRNPL | skeletal muscle; myocytes[Uncertain,High] |
| HPA:002010_13 | 0.0125874733426 | 0.75 | RBMX HNRNPK HNRNPL | appendix; glandular cells[Supported,High] |
| HPA:016010_13 | 0.0125874733426 | 0.75 | RBMX HNRNPK HNRNPL | esophagus; squamous epithelial cells[Supported,High] |
| HPA:043040_03 | 0.0125874733426 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; melanocytes[Uncertain,High] |
| HPA:008030_13 | 0.0129586703655 | 0.75 | RBMX HNRNPK HNRNPL | cerebral cortex; neuronal cells[Supported,High] |
| HPA:015010_13 | 0.0135289372622 | 0.75 | RBMX HNRNPK HNRNPL | epididymis; glandular cells[Supported,High] |
| HPA:024020_13 | 0.0137226518885 | 0.75 | RBMX HNRNPK HNRNPL | kidney; cells in tubules[Supported,High] |
| CORUM:1181 | 0.0149958507614 | 0.5 | RBMX HNRNPK | C complex spliceosome |
| HPA:031010_11 | 0.0164101932347 | 0.75 | RBMX HNRNPK HNRNPL | ovary; follicle cells[Supported,Low] |
| HPA:006020_03 | 0.01651997263 | 0.75 | RBMX HNRNPK HNRNPL | caudate; neuronal cells[Uncertain,High] |
| HPA:007030_03 | 0.01651997263 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in molecular layer[Uncertain,High] |
| KEGG:03040 | 0.016608760826 | 0.5 | RBMX HNRNPK | Spliceosome |
| HPA:055010_13 | 0.0170761600268 | 0.75 | RBMX HNRNPK HNRNPL | thyroid gland; glandular cells[Supported,High] |
| HPA:009020_03 | 0.0170761600268 | 0.75 | RBMX HNRNPK HNRNPL | cervix, uterine; squamous epithelial cells[Uncertain,High] |
| HPA:053020_13 | 0.017188862818 | 0.75 | RBMX HNRNPK HNRNPL | testis; cells in seminiferous ducts[Supported,High] |
| HPA:014010_12 | 0.0185798771417 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 2; cells in endometrial stroma[Supported,Medium] |
| HPA:047040_11 | 0.0186990413257 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; peripheral nerve[Supported,Low] |
| HPA:001040_13 | 0.0188187097484 | 0.75 | RBMX HNRNPK HNRNPL | adrenal gland; glandular cells[Supported,High] |
| HPA:057010_13 | 0.0188187097484 | 0.75 | RBMX HNRNPK HNRNPL | urinary bladder; urothelial cells[Supported,High] |
| HPA:056010_03 | 0.019302446397 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; germinal center cells[Uncertain,High] |
| HPA:022010_12 | 0.0205475883704 | 0.75 | RBMX HNRNPK HNRNPL | hippocampus; glial cells[Supported,Medium] |
| HPA:018010_13 | 0.0209312173501 | 0.75 | RBMX HNRNPK HNRNPL | fallopian tube; glandular cells[Supported,High] |
| HPA:029010_13 | 0.0210601377494 | 0.75 | RBMX HNRNPK HNRNPL | nasopharynx; respiratory epithelial cells[Supported,High] |
| HPA:005010_13 | 0.0211895818928 | 0.75 | RBMX HNRNPK HNRNPL | bronchus; respiratory epithelial cells[Supported,High] |
| HPA:022020_03 | 0.021450045509 | 0.75 | RBMX HNRNPK HNRNPL | hippocampus; neuronal cells[Uncertain,High] |
| HPA:058010_03 | 0.0217126163903 | 0.75 | RBMX HNRNPK HNRNPL | vagina; squamous epithelial cells[Uncertain,High] |
| HPA:052010_13 | 0.0221104417449 | 0.75 | RBMX HNRNPK HNRNPL | stomach 2; glandular cells[Supported,High] |
| HPA:045010_13 | 0.0234712568487 | 0.75 | RBMX HNRNPK HNRNPL | small intestine; glandular cells[Supported,High] |
| HPA:051010_13 | 0.0237498929607 | 0.75 | RBMX HNRNPK HNRNPL | stomach 1; glandular cells[Supported,High] |
| HPA:011020_13 | 0.0244560243519 | 0.75 | RBMX HNRNPK HNRNPL | colon; glandular cells[Supported,High] |
| HPA:056020_03 | 0.0244560243519 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; non-germinal center cells[Uncertain,High] |
| HPA:035020_13 | 0.025175887812 | 0.75 | RBMX HNRNPK HNRNPL | placenta; trophoblastic cells[Supported,High] |
| HPA:013010_12 | 0.02561445023 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 1; cells in endometrial stroma[Supported,Medium] |
| HPA:031020_12 | 0.0259096106078 | 0.75 | RBMX HNRNPK HNRNPL | ovary; ovarian stroma cells[Supported,Medium] |
| HPA:048030_12 | 0.026506652998 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 2; fibroblasts[Supported,Medium] |
| HPA:009010_03 | 0.026657319863 | 0.75 | RBMX HNRNPK HNRNPL | cervix, uterine; glandular cells[Uncertain,High] |
| HPA:014020_03 | 0.0269603482222 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 2; glandular cells[Uncertain,High] |
| HPA:047030_12 | 0.0281952055319 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; fibroblasts[Supported,Medium] |
| HPA:012010_13 | 0.0283521381117 | 0.75 | RBMX HNRNPK HNRNPL | duodenum; glandular cells[Supported,High] |
| HPA:050020_12 | 0.0296284087039 | 0.75 | RBMX HNRNPK HNRNPL | spleen; cells in white pulp[Supported,Medium] |
| HPA:037010_13 | 0.0296284087039 | 0.75 | RBMX HNRNPK HNRNPL | rectum; glandular cells[Supported,High] |
| HPA:048040_11 | 0.0306101023554 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 2; peripheral nerve[Supported,Low] |
| HPA:013020_03 | 0.0307757765426 | 0.75 | RBMX HNRNPK HNRNPL | endometrium 1; glandular cells[Uncertain,High] |
| HPA:011030_12 | 0.0312763482879 | 0.75 | RBMX HNRNPK HNRNPL | colon; peripheral nerve/ganglion[Supported,Medium] |
| HPA:026020_12 | 0.031444391961 | 0.75 | RBMX HNRNPK HNRNPL | liver; hepatocytes[Supported,Medium] |
| HPA:046010_12 | 0.0316130305275 | 0.75 | RBMX HNRNPK HNRNPL | smooth muscle; smooth muscle cells[Supported,Medium] |
| HPA:019010_13 | 0.0338599256539 | 0.75 | RBMX HNRNPK HNRNPL | gallbladder; glandular cells[Supported,High] |
| HPA:008020_12 | 0.0340369984952 | 0.75 | RBMX HNRNPK HNRNPL | cerebral cortex; glial cells[Supported,Medium] |
| HPA:004010_11 | 0.0342146813303 | 0.75 | RBMX HNRNPK HNRNPL | breast; adipocytes[Supported,Low] |
| HPA:047020_02 | 0.0352936444685 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; chondrocytes[Uncertain,Medium] |
| HPA:047040_13 | 0.0358677115697 | 0.5 | HNRNPL HNRNPK | soft tissue 1; peripheral nerve[Supported,High] |
| HPA:056030_03 | 0.0362097393399 | 0.75 | RBMX HNRNPK HNRNPL | tonsil; squamous epithelial cells[Uncertain,High] |
| HPA:007020_12 | 0.0365805245307 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in granular layer[Supported,Medium] |
| HPA:047010_11 | 0.0382800635721 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; adipocytes[Supported,Low] |
| HPA:024010_12 | 0.038664676769 | 0.75 | RBMX HNRNPK HNRNPL | kidney; cells in glomeruli[Supported,Medium] |
| HPA:047040_02 | 0.0390518301534 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 1; peripheral nerve[Uncertain,Medium] |
| HPA:050010_12 | 0.0410259794916 | 0.75 | RBMX HNRNPK HNRNPL | spleen; cells in red pulp[Supported,Medium] |
| HPA:039010_03 | 0.0416307958449 | 0.75 | RBMX HNRNPK HNRNPL | salivary gland; glandular cells[Uncertain,High] |
| HPA:027020_12 | 0.0418336999884 | 0.75 | RBMX HNRNPK HNRNPL | lung; pneumocytes[Supported,Medium] |
| HPA:041010_12 | 0.0438987109299 | 0.75 | RBMX HNRNPK HNRNPL | skeletal muscle; myocytes[Supported,Medium] |
| HPA:007030_12 | 0.0447431662559 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; cells in molecular layer[Supported,Medium] |
| HPA:011010_12 | 0.0447431662559 | 0.75 | RBMX HNRNPK HNRNPL | colon; endothelial cells[Supported,Medium] |
| HPA:007010_03 | 0.0451693794799 | 0.75 | RBMX HNRNPK HNRNPL | cerebellum; Purkinje cells[Uncertain,High] |
| HPA:043020_12 | 0.0458137035926 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; fibroblasts[Supported,Medium] |
| HPA:032020_12 | 0.0460298167372 | 0.75 | RBMX HNRNPK HNRNPL | pancreas; islets of Langerhans[Supported,Medium] |
| HPA:006020_12 | 0.0462466007541 | 0.75 | RBMX HNRNPK HNRNPL | caudate; neuronal cells[Supported,Medium] |
| HPA:043010_12 | 0.0462466007541 | 0.75 | RBMX HNRNPK HNRNPL | skin 1; Langerhans[Supported,Medium] |
| HPA:002020_12 | 0.0469009879466 | 0.75 | RBMX HNRNPK HNRNPL | appendix; lymphoid tissue[Supported,Medium] |
| HPA:048040_02 | 0.0471204653595 | 0.75 | RBMX HNRNPK HNRNPL | soft tissue 2; peripheral nerve[Uncertain,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HNRNPK | HNRNPL | 0.988 | 0.902 | hein_WMM bioplex (HNRNPK) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| LDHB | HNRNPK | 0.838 | 0.782 | bioplex (HNRNPK,LDHB) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| RBMX | HNRNPK | 0.73 | 0.735 | hein_WMM bioplex (HNRNPK,RBMX) bioplex_WMM fraction treiber_WMM |
| RBMX | HNRNPL | 0.008 | 0.035 | hein_WMM bioplex (RBMX) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| LDHB | HNRNPL | 0.007 | 0.004 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| LDHB | RBMX | 0.007 | 0.003 | bioplex (RBMX) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
Images
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Complex HuMAP2_03721 has an average edge precision of 0.41 which is ranked 3196 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RBMX | HuMAP2_01393 HuMAP2_02261 HuMAP2_03721 HuMAP2_04343 HuMAP2_05678 HuMAP2_06411 |
| HNRNPL | HuMAP2_03721 HuMAP2_04515 |
| HNRNPK | HuMAP2_02471 HuMAP2_03721 |
| LDHB | HuMAP2_00244 HuMAP2_01375 HuMAP2_03721 HuMAP2_05958 HuMAP2_06602 HuMAP2_06767 HuMAP2_06910 |