hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03733
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK5RAP3 | CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27) | UniProt NCBI |
| UFL1 | E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1) | UniProt NCBI |
| DDRGK1 | DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1) | UniProt NCBI |
| BICD2 | Protein bicaudal D homolog 2 (Bic-D 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0071569 | 7.26438828159e-06 | 0.75 | DDRGK1 UFL1 CDK5RAP3 | protein ufmylation |
| GO:1990564 | 0.0270421395626 | 0.5 | DDRGK1 UFL1 | protein polyufmylation |
| GO:1990592 | 0.0270421395626 | 0.5 | DDRGK1 UFL1 | protein K69-linked ufmylation |
| MIRNA:hsa-miR-6730-3p | 0.0346755687702 | 0.5 | BICD2 UFL1 | hsa-miR-6730-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDRGK1 | UFL1 | 1.0 | 0.949 | hein_WMM bioplex (DDRGK1) bioplex_WMM youn_WMM hein (UFL1) gupta_WMM |
| UFL1 | CDK5RAP3 | 0.991 | 0.909 | hein_WMM bioplex (CDK5RAP3) bioplex_WMM youn_WMM hein (UFL1) |
| DDRGK1 | CDK5RAP3 | 0.874 | 0.807 | hein_WMM bioplex (CDK5RAP3,DDRGK1) bioplex_WMM youn_WMM gupta_WMM |
| CDK5RAP3 | BICD2 | 0.053 | 0.301 | fraction |
| DDRGK1 | BICD2 | 0.0 | 0.002 | bioplex_WMM fraction |
Images
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Complex HuMAP2_03733 has an average edge precision of 0.594 which is ranked 1973 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDK5RAP3 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| UFL1 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| DDRGK1 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| BICD2 | HuMAP2_02644 HuMAP2_03733 |