hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03741
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPP6R1 | Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1) | UniProt NCBI |
| ANKRD44 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) | UniProt NCBI |
| NOTCH2 | Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3154 | 0.0249904952816 | 0.333333333333 | NOTCH2 | Notch2(N-TM)-Notch2(N-EC)-Delta complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP6R1 | ANKRD44 | 1.0 | 0.949 | hein_WMM bioplex (ANKRD44) bioplex_WMM youn_WMM hein (PPP6R1) |
| NOTCH2 | ANKRD44 | 0.873 | 0.805 | bioplex (ANKRD44) bioplex_WMM |
| NOTCH2 | PPP6R1 | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_03741 has an average edge precision of 0.585 which is ranked 2009 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPP6R1 | HuMAP2_02481 HuMAP2_03741 HuMAP2_05435 HuMAP2_06268 |
| ANKRD44 | HuMAP2_02481 HuMAP2_03741 HuMAP2_05435 HuMAP2_06153 HuMAP2_06268 |
| NOTCH2 | HuMAP2_01320 HuMAP2_03741 HuMAP2_06153 HuMAP2_06268 |