hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03762
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ADAR | Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP) | UniProt NCBI |
| BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1) | UniProt NCBI |
| BTBD10 | BTB/POZ domain-containing protein 10 (Glucose metabolism-related protein 1) | UniProt NCBI |
| BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A) | UniProt NCBI |
| CDC20 | Cell division cycle protein 20 homolog (p55CDC) | UniProt NCBI |
| BUB3 | Mitotic checkpoint protein BUB3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4240 | 3.02401526514e-10 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Regulation of sister chromatid separation at the metaphase-anaphase transition |
| CORUM:190 | 9.01288868683e-09 | 0.5 | CDC20 BUB1B BUB3 | Mitotic checkpoint complex (MCC) |
| HP:0100650 | 1.12933306268e-06 | 0.5 | BUB1 BUB3 BUB1B | Vaginal neoplasm |
| KEGG:04110 | 2.74873837611e-06 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Cell cycle |
| REAC:R-HSA-141424 | 3.32075312801e-06 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Amplification of signal from the kinetochores |
| REAC:R-HSA-141444 | 3.32075312801e-06 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141405 | 5.75676182894e-06 | 0.5 | CDC20 BUB1B BUB3 | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| REAC:R-HSA-141430 | 5.75676182894e-06 | 0.5 | CDC20 BUB1B BUB3 | Inactivation of APC/C via direct inhibition of the APC/C complex |
| REAC:R-HSA-69618 | 6.12327343665e-06 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Mitotic Spindle Checkpoint |
| CORUM:1851 | 8.39001385941e-06 | 0.333333333333 | BUB1 BUB3 | BUB1-BUB3 complex |
| HP:0001682 | 9.16612699891e-06 | 0.5 | BUB1 BUB3 BUB1B | Subvalvular aortic stenosis |
| REAC:R-HSA-2500257 | 9.73323752851e-06 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Resolution of Sister Chromatid Cohesion |
| GO:0071173 | 1.00004074113e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | spindle assembly checkpoint |
| GO:0007094 | 1.00004074113e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic spindle assembly checkpoint |
| GO:0071174 | 1.00004074113e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic spindle checkpoint |
| GO:0031577 | 1.00004074113e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | spindle checkpoint |
| HP:0011103 | 1.12796815876e-05 | 0.5 | BUB1 BUB3 BUB1B | Abnormal left ventricular outflow tract morphology |
| GO:0045841 | 1.14807138073e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of mitotic metaphase/anaphase transition |
| REAC:R-HSA-179409 | 1.20153549581e-05 | 0.5 | CDC20 BUB1B BUB3 | APC-Cdc20 mediated degradation of Nek2A |
| GO:1902100 | 1.31194039242e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of metaphase/anaphase transition of cell cycle |
| HP:0006721 | 1.36946854865e-05 | 0.5 | BUB1 BUB3 BUB1B | Acute lymphoblastic leukemia |
| REAC:R-HSA-5663220 | 1.47397775141e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | RHO GTPases Activate Formins |
| GO:2000816 | 1.49273703752e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of mitotic sister chromatid separation |
| GO:1905819 | 1.69158658226e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of chromosome separation |
| GO:0033048 | 2.14812534311e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of mitotic sister chromatid segregation |
| HP:0002859 | 2.2948325134e-05 | 0.5 | BUB1 BUB3 BUB1B | Rhabdomyosarcoma |
| GO:0033046 | 2.69127816091e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of sister chromatid segregation |
| GO:0051985 | 2.99853000209e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of chromosome segregation |
| HP:0012126 | 3.09909944032e-05 | 0.5 | BUB1 BUB3 BUB1B | Stomach cancer |
| HP:0001909 | 3.41088604816e-05 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Leukemia |
| HP:0009728 | 4.6264255405e-05 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of striated muscle |
| GO:0030071 | 4.94625447876e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of mitotic metaphase/anaphase transition |
| HP:0002247 | 5.2290813676e-05 | 0.5 | BUB1 BUB3 BUB1B | Duodenal atresia |
| HP:0010880 | 5.2290813676e-05 | 0.5 | BUB1 BUB3 BUB1B | Increased nuchal translucency |
| REAC:R-HSA-2467813 | 5.32074208241e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Separation of Sister Chromatids |
| GO:1902099 | 5.42823133593e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of metaphase/anaphase transition of cell cycle |
| GO:0045839 | 5.42823133593e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of mitotic nuclear division |
| HP:0030724 | 6.14216680087e-05 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Central nervous system cyst |
| HP:0010576 | 6.14216680087e-05 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Intracranial cystic lesion |
| REAC:R-HSA-68877 | 6.31725452927e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Mitotic Prometaphase |
| REAC:R-HSA-68882 | 6.31725452927e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 6.45096420202e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Mitotic Metaphase and Anaphase |
| GO:0007091 | 6.49684869516e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | metaphase/anaphase transition of mitotic cell cycle |
| GO:0044784 | 7.08670803224e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | metaphase/anaphase transition of cell cycle |
| GO:0051784 | 7.71580656381e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of nuclear division |
| GO:0010965 | 7.71580656381e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of mitotic sister chromatid separation |
| GO:0051306 | 9.09855163313e-05 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic sister chromatid separation |
| GO:1905818 | 0.000106591013601 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of chromosome separation |
| HP:0002101 | 0.000109614122056 | 0.5 | BUB1 BUB3 BUB1B | Abnormal lung lobation |
| HP:0011100 | 0.000131452960702 | 0.5 | BUB1 BUB3 BUB1B | Intestinal atresia |
| HP:0002667 | 0.000143381531621 | 0.5 | BUB1 BUB3 BUB1B | Nephroblastoma |
| HP:0003003 | 0.00015600923299 | 0.5 | BUB1 BUB3 BUB1B | Colon cancer |
| HP:0011794 | 0.00015600923299 | 0.5 | BUB1 BUB3 BUB1B | Embryonal renal neoplasm |
| HP:0011119 | 0.000168739236629 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the nasal dorsum |
| GO:0033047 | 0.000177369828603 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of mitotic sister chromatid segregation |
| HP:0001679 | 0.000267973034972 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal aortic morphology |
| HP:0000821 | 0.000289880677921 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Hypothyroidism |
| HP:0200008 | 0.000304375323156 | 0.5 | BUB1 BUB3 BUB1B | Intestinal polyposis |
| HP:0004377 | 0.000313099655019 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Hematological neoplasm |
| REAC:R-HSA-69620 | 0.000322105305692 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Cell Cycle Checkpoints |
| HP:0002926 | 0.000331404976924 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of thyroid physiology |
| GO:0033045 | 0.000333147323349 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of sister chromatid segregation |
| REAC:R-HSA-174184 | 0.000336891436266 | 0.5 | CDC20 BUB1B BUB3 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
| REAC:R-HSA-179419 | 0.000351485615181 | 0.5 | CDC20 BUB1B BUB3 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint |
| HP:0002898 | 0.000369253258459 | 0.5 | BUB1 BUB3 BUB1B | Embryonal neoplasm |
| WP:WP179 | 0.000374020007573 | 0.5 | CDC20 BUB1 BUB3 | Cell Cycle |
| REAC:R-HSA-176409 | 0.000381921489935 | 0.5 | CDC20 BUB1B BUB3 | APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-176814 | 0.000397774586562 | 0.5 | CDC20 BUB1B BUB3 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
| HP:0100273 | 0.000417247653264 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of the colon |
| HP:0002589 | 0.000417247653264 | 0.5 | BUB1 BUB3 BUB1B | Gastrointestinal atresia |
| HP:0005266 | 0.000417247653264 | 0.5 | BUB1 BUB3 BUB1B | Intestinal polyp |
| GO:0051304 | 0.000417891539136 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | chromosome separation |
| REAC:R-HSA-195258 | 0.000432427470222 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | RHO GTPase Effectors |
| REAC:R-HSA-176408 | 0.000465554212544 | 0.5 | CDC20 BUB1B BUB3 | Regulation of APC/C activators between G1/S and early anaphase |
| HP:0007565 | 0.000469218904624 | 0.5 | BUB1 BUB3 BUB1B | Multiple cafe-au-lait spots |
| HP:0001360 | 0.000496744784051 | 0.5 | BUB1 BUB3 BUB1B | Holoprosencephaly |
| HP:0002246 | 0.000496744784051 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the duodenum |
| HP:0001659 | 0.000554974810191 | 0.5 | BUB1 BUB3 BUB1B | Aortic regurgitation |
| REAC:R-HSA-453276 | 0.00058095037578 | 0.5 | CDC20 BUB1B BUB3 | Regulation of mitotic cell cycle |
| REAC:R-HSA-174143 | 0.00058095037578 | 0.5 | CDC20 BUB1B BUB3 | APC/C-mediated degradation of cell cycle proteins |
| HP:0006753 | 0.000585718024741 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of the stomach |
| HP:0000501 | 0.000629046311597 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Glaucoma |
| HP:0001680 | 0.000650558436223 | 0.5 | BUB1 BUB3 BUB1B | Coarctation of aorta |
| HP:0002797 | 0.000756496387193 | 0.5 | BUB1 BUB3 BUB1B | Osteolysis |
| HP:0002863 | 0.000756496387193 | 0.5 | BUB1 BUB3 BUB1B | Myelodysplasia |
| HP:0100834 | 0.000873314294634 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of the large intestine |
| GO:0051983 | 0.000926409268263 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of chromosome segregation |
| REAC:R-HSA-68886 | 0.000954435464227 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | M Phase |
| HP:0000820 | 0.00113781647792 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the thyroid gland |
| HP:0001541 | 0.00114168764513 | 0.5 | BUB1 BUB3 BUB1B | Ascites |
| HP:0000142 | 0.00124200653741 | 0.5 | BUB1 BUB3 BUB1B | Abnormal vagina morphology |
| HP:0003560 | 0.00140319898651 | 0.5 | BUB1 BUB3 BUB1B | Muscular dystrophy |
| REAC:R-HSA-194315 | 0.00160911313747 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Signaling by Rho GTPases |
| HP:0001711 | 0.00170171010284 | 0.5 | BUB1 BUB3 BUB1B | Abnormal left ventricle morphology |
| HP:0002488 | 0.00176606420523 | 0.5 | BUB1 BUB3 BUB1B | Acute leukemia |
| HP:0011004 | 0.00177010317298 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal systemic arterial morphology |
| HP:0030448 | 0.00183201380014 | 0.5 | BUB1 BUB3 BUB1B | Soft tissue sarcoma |
| HP:0000445 | 0.00183201380014 | 0.5 | BUB1 BUB3 BUB1B | Wide nose |
| HP:0001000 | 0.00199789335791 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of skin pigmentation |
| KEGG:05166 | 0.00204927990704 | 0.5 | CDC20 BUB1B BUB3 | Human T-cell leukemia virus 1 infection |
| HP:0009726 | 0.00218636590141 | 0.5 | BUB1 BUB3 BUB1B | Renal neoplasm |
| HP:0000957 | 0.00241935032153 | 0.5 | BUB1 BUB3 BUB1B | Cafe-au-lait spot |
| HP:0000062 | 0.002500522119 | 0.5 | BUB1 BUB3 BUB1B | Ambiguous genitalia |
| HP:0000003 | 0.00275483584429 | 0.5 | BUB1 BUB3 BUB1B | Multicystic kidney dysplasia |
| HP:0000325 | 0.00275483584429 | 0.5 | BUB1 BUB3 BUB1B | Triangular face |
| GO:2001251 | 0.00306979744334 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of chromosome organization |
| REAC:R-HSA-69278 | 0.00331294271573 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Cell Cycle, Mitotic |
| HP:0000457 | 0.00351554680502 | 0.5 | BUB1 BUB3 BUB1B | Depressed nasal ridge |
| HP:0031652 | 0.00351554680502 | 0.5 | BUB1 BUB3 BUB1B | Abnormal aortic valve physiology |
| HP:0030962 | 0.0035891046318 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal morphology of the great vessels |
| HP:0010786 | 0.00361941962178 | 0.5 | BUB1 BUB3 BUB1B | Urinary tract neoplasm |
| HP:0100242 | 0.00383322991569 | 0.5 | BUB1 BUB3 BUB1B | Sarcoma |
| HP:0001305 | 0.00394320526633 | 0.5 | BUB1 BUB3 BUB1B | Dandy-Walker malformation |
| HP:0005445 | 0.00405525264868 | 0.5 | BUB1 BUB3 BUB1B | Widened posterior fossa |
| HP:0010787 | 0.00428563912502 | 0.5 | BUB1 BUB3 BUB1B | Genital neoplasm |
| GO:0007088 | 0.00436089686659 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of mitotic nuclear division |
| HP:0010950 | 0.00489918791641 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the fourth ventricle |
| HP:0002198 | 0.00489918791641 | 0.5 | BUB1 BUB3 BUB1B | Dilated fourth ventricle |
| HP:0002350 | 0.00502849121292 | 0.5 | BUB1 BUB3 BUB1B | Cerebellar cyst |
| HP:0002577 | 0.00510933828714 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the stomach |
| HP:0010987 | 0.00515743219305 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal cellular immune system morphology |
| HP:0001881 | 0.00515743219305 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal leukocyte morphology |
| GO:0000070 | 0.00537058982175 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic sister chromatid segregation |
| GO:0051783 | 0.00552795012078 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | regulation of nuclear division |
| HP:0032251 | 0.00570898035154 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal immune system morphology |
| HP:0000932 | 0.00570901006754 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the posterior cranial fossa |
| REAC:R-HSA-1640170 | 0.00675311119139 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | Cell Cycle |
| GO:0051754 | 0.00676235117068 | 0.333333333333 | BUB1 BUB1B | meiotic sister chromatid cohesion, centromeric |
| GO:0007093 | 0.006914256367 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic cell cycle checkpoint |
| HP:0002693 | 0.0070826612539 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the skull base |
| HP:0000340 | 0.00829057557506 | 0.5 | BUB1 BUB3 BUB1B | Sloping forehead |
| HP:0002119 | 0.00857296153256 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Ventriculomegaly |
| GO:0000819 | 0.0107072105801 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | sister chromatid segregation |
| HP:0007379 | 0.0110999618929 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of the genitourinary tract |
| HP:0000369 | 0.0122955534548 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Low-set ears |
| HP:0007370 | 0.0126678913364 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Aplasia/Hypoplasia of the corpus callosum |
| HP:0001320 | 0.0139573410906 | 0.5 | BUB1 BUB3 BUB1B | Cerebellar vermis hypoplasia |
| HP:0002250 | 0.0139573410906 | 0.5 | BUB1 BUB3 BUB1B | Abnormal large intestine morphology |
| HP:0001561 | 0.0152783894038 | 0.5 | BUB1 BUB3 BUB1B | Polyhydramnios |
| HP:0000357 | 0.0155135678776 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal location of ears |
| HP:0001438 | 0.0158443316134 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of abdomen morphology |
| HP:0002244 | 0.0163927867751 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the small intestine |
| HP:0001273 | 0.0176975810126 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal corpus callosum morphology |
| GO:0000075 | 0.0184709841663 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | cell cycle checkpoint |
| HP:0025015 | 0.0190617513532 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormal vascular morphology |
| HP:0000348 | 0.0200551569888 | 0.5 | BUB1 BUB3 BUB1B | High forehead |
| HP:0006817 | 0.0200551569888 | 0.5 | BUB1 BUB3 BUB1B | Aplasia/Hypoplasia of the cerebellar vermis |
| GO:0045144 | 0.020283420769 | 0.333333333333 | BUB1 BUB1B | meiotic sister chromatid segregation |
| GO:0051177 | 0.020283420769 | 0.333333333333 | BUB1 BUB1B | meiotic sister chromatid cohesion |
| GO:0007135 | 0.020283420769 | 0.333333333333 | BUB1 BUB1B | meiosis II |
| GO:0061983 | 0.020283420769 | 0.333333333333 | BUB1 BUB1B | meiosis II cell cycle process |
| HP:0007378 | 0.0213861967068 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm of the gastrointestinal tract |
| HP:0007957 | 0.0213861967068 | 0.5 | BUB1 BUB3 BUB1B | Corneal opacity |
| HP:0002648 | 0.0221643816853 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of calvarial morphology |
| HP:0002118 | 0.0221643816853 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the cerebral ventricles |
| GO:1901991 | 0.0222594167129 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of mitotic cell cycle phase transition |
| HP:0000368 | 0.0238534736244 | 0.5 | BUB1 BUB3 BUB1B | Low-set, posteriorly rotated ears |
| HP:0000568 | 0.0253441504586 | 0.5 | BUB1 BUB3 BUB1B | Microphthalmia |
| HP:0011355 | 0.0264290937445 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Localized skin lesion |
| HP:0002104 | 0.0265015994402 | 0.5 | BUB1 BUB3 BUB1B | Apnea |
| GO:0098813 | 0.02660044644 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | nuclear chromosome segregation |
| HP:0011793 | 0.0279206634233 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Neoplasm by anatomical site |
| HP:0000107 | 0.028507232728 | 0.5 | BUB1 BUB3 BUB1B | Renal cyst |
| GO:1901988 | 0.0287203705471 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | negative regulation of cell cycle phase transition |
| HP:0002334 | 0.0289200021372 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of the cerebellar vermis |
| HP:0002500 | 0.0310897526003 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the cerebral white matter |
| HP:0002664 | 0.0331529578102 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Neoplasm |
| HP:0100887 | 0.0341842384581 | 0.5 | BUB1 BUB3 BUB1B | Abnormality of globe size |
| HP:0010938 | 0.0343201422612 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the external nose |
| KEGG:04114 | 0.0348461971614 | 0.333333333333 | CDC20 BUB1 | Oocyte meiosis |
| HP:0031653 | 0.0355921289237 | 0.5 | BUB1 BUB3 BUB1B | Abnormal heart valve physiology |
| HP:0004209 | 0.0380225871731 | 0.5 | BUB1 BUB3 BUB1B | Clinodactyly of the 5th finger |
| GO:0140014 | 0.0384847308813 | 0.666666666667 | CDC20 BUB1 BUB3 BUB1B | mitotic nuclear division |
| HP:0009179 | 0.0390245705401 | 0.5 | BUB1 BUB3 BUB1B | Deviation of the 5th finger |
| HP:0002683 | 0.0399525789326 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the calvaria |
| HP:0011792 | 0.0421345110279 | 0.5 | BUB1 BUB3 BUB1B | Neoplasm by histology |
| HP:0010993 | 0.0479843212756 | 0.666666666667 | ADAR BUB1 BUB3 BUB1B | Abnormality of the cerebral subcortex |
| CORUM:2718 | 0.0499726005494 | 0.166666666667 | CDC20 | MAD2-CDC20 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BUB1B | BUB3 | 1.0 | 0.949 | hein_WMM bioplex (BUB3) bioplex_WMM youn_WMM hein (BUB1B,BUB3) gupta_WMM |
| BUB1 | BUB3 | 0.998 | 0.944 | hein_WMM bioplex (BUB1,BUB3) bioplex_WMM youn_WMM hein (BUB1,BUB3) |
| CDC20 | BUB1B | 0.82 | 0.773 | hein_WMM bioplex (CDC20) bioplex_WMM youn_WMM hein (BUB1B,CDC20) gupta_WMM |
| BUB1B | BUB1 | 0.179 | 0.438 | hein_WMM bioplex (BUB1) bioplex_WMM youn_WMM |
| CDC20 | BUB3 | 0.128 | 0.398 | hein_WMM bioplex (BUB3,CDC20) bioplex_WMM youn_WMM hein (CDC20) gupta_WMM |
| BUB3 | ADAR | 0.066 | 0.349 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| BUB3 | BTBD10 | 0.05 | 0.295 | bioplex (BUB3) bioplex_WMM |
| CDC20 | BUB1 | 0.011 | 0.145 | hein_WMM bioplex (BUB1) bioplex_WMM youn_WMM hein (BUB1,CDC20) |
| BUB1 | BTBD10 | 0.009 | 0.091 | bioplex_WMM WMM_only |
| BUB1B | BTBD10 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| CDC20 | BTBD10 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| BUB1B | ADAR | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
| BUB1 | ADAR | 0.007 | 0.001 | youn_WMM WMM_only |
| CDC20 | ADAR | 0.006 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_03762 has an average edge precision of 0.322 which is ranked 4318 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ADAR | HuMAP2_03762 HuMAP2_05126 HuMAP2_05859 |
| BUB1B | HuMAP2_00635 HuMAP2_03465 HuMAP2_03762 HuMAP2_05264 |
| BTBD10 | HuMAP2_03465 HuMAP2_03762 HuMAP2_03890 HuMAP2_05859 |
| BUB1 | HuMAP2_03465 HuMAP2_03762 HuMAP2_05264 |
| CDC20 | HuMAP2_00635 HuMAP2_03601 HuMAP2_03762 |
| BUB3 | HuMAP2_03465 HuMAP2_03762 HuMAP2_05264 HuMAP2_05859 |