hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03773
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TNFSF13B | Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form] | UniProt NCBI |
| MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) | UniProt NCBI |
| FAM160B1 | Protein FAM160B1 | UniProt NCBI |
| MAP3K15 | Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15) | UniProt NCBI |
| HOOK2 | Protein Hook homolog 2 (h-hook2) (hHK2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5691 | 0.0249780992026 | 0.2 | TNFSF13B | TALL1 homo-oligomer complex |
| CORUM:6120 | 0.0499494897235 | 0.2 | HOOK2 | Hook2-Vps16 complex |
| CORUM:6121 | 0.0499494897235 | 0.2 | HOOK2 | Hook2-Vps41 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAP3K15 | TNFSF13B | 0.984 | 0.899 | bioplex (TNFSF13B) bioplex_WMM |
| FAM160B1 | TNFSF13B | 0.974 | 0.886 | bioplex (TNFSF13B) bioplex_WMM |
| HOOK2 | TNFSF13B | 0.817 | 0.773 | bioplex (TNFSF13B) bioplex_WMM |
| TNFSF13B | MAP3K5 | 0.791 | 0.758 | bioplex (TNFSF13B) bioplex_WMM |
| FAM160B1 | HOOK2 | 0.011 | 0.143 | bioplex_WMM WMM_only |
| MAP3K15 | MAP3K5 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| FAM160B1 | MAP3K5 | 0.009 | 0.101 | bioplex_WMM WMM_only |
| MAP3K15 | FAM160B1 | 0.009 | 0.099 | bioplex_WMM WMM_only |
| HOOK2 | MAP3K5 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| MAP3K15 | HOOK2 | 0.008 | 0.077 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03773 has an average edge precision of 0.393 which is ranked 3401 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TNFSF13B | HuMAP2_03773 HuMAP2_04886 |
| MAP3K5 | HuMAP2_03773 HuMAP2_04886 |
| FAM160B1 | HuMAP2_02675 HuMAP2_03773 HuMAP2_04886 |
| MAP3K15 | HuMAP2_02307 HuMAP2_03773 HuMAP2_04886 |
| HOOK2 | HuMAP2_03373 HuMAP2_03773 HuMAP2_03893 HuMAP2_04886 HuMAP2_05370 |