hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03778
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GLYR1 | Putative oxidoreductase GLYR1 (EC 1.-.-.-) (3-hydroxyisobutyrate dehydrogenase-like protein) (Cytokine-like nuclear factor N-PAC) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) | UniProt NCBI |
| NOP58 | Nucleolar protein 58 (Nucleolar protein 5) | UniProt NCBI |
| FBL | rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) | UniProt NCBI |
| GNL3 | Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin) | UniProt NCBI |
| CEBPZ | CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) | UniProt NCBI |
| NOP56 | Nucleolar protein 56 (Nucleolar protein 5A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03008 | 4.54936912922e-07 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | Ribosome biogenesis in eukaryotes |
| CORUM:3055 | 1.90909466772e-06 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | Nop56p-associated pre-rRNA complex |
| GO:0031428 | 1.81582264982e-05 | 0.5 | NOP56 FBL NOP58 | box C/D snoRNP complex |
| REAC:R-HSA-6791226 | 5.09116254048e-05 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 6.31725452927e-05 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 7.75166031651e-05 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | rRNA processing |
| REAC:R-HSA-6790901 | 0.000202041038028 | 0.5 | NOP56 FBL NOP58 | rRNA modification in the nucleus and cytosol |
| GO:0005732 | 0.00175581235783 | 0.5 | NOP56 FBL NOP58 | small nucleolar ribonucleoprotein complex |
| REAC:R-HSA-8953854 | 0.00833913786065 | 0.666666666667 | NOP56 NOP58 FBL GNL3 | Metabolism of RNA |
| GO:0032040 | 0.0129043378459 | 0.5 | NOP56 FBL NOP58 | small-subunit processome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FBL | NOP58 | 1.0 | 0.949 | hein_WMM bioplex (FBL) bioplex_WMM Guru hein (FBL) gupta_WMM fraction treiber_WMM |
| NOP56 | FBL | 1.0 | 0.949 | hein_WMM bioplex (FBL) bioplex_WMM hein (FBL,NOP56) gupta_WMM fraction treiber_WMM |
| NOP56 | NOP58 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (NOP56) Malo gupta_WMM fraction treiber_WMM |
| NOP56 | GNL3 | 0.948 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| CEBPZ | NOP56 | 0.761 | 0.749 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| NOP56 | GLYR1 | 0.752 | 0.745 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| GNL3 | GLYR1 | 0.03 | 0.239 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NOP58 | GNL3 | 0.012 | 0.147 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| CEBPZ | GNL3 | 0.01 | 0.106 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| CEBPZ | GLYR1 | 0.01 | 0.104 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| FBL | GLYR1 | 0.006 | 0.003 | hein_WMM bioplex (FBL) bioplex_WMM gupta_WMM fraction treiber_WMM |
| NOP58 | GLYR1 | 0.005 | 0.009 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| CEBPZ | NOP58 | 0.0 | 0.01 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| FBL | GNL3 | 0.0 | 0.0 | hein_WMM bioplex (FBL) bioplex_WMM gupta_WMM treiber_WMM |
| CEBPZ | FBL | 0.0 | 0.004 | hein_WMM bioplex (FBL) bioplex_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_03778 has an average edge precision of 0.388 which is ranked 3447 out of all 6965 complexes.
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