hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03797
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UNG | Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) | UniProt NCBI |
| FBXL16 | F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16) | UniProt NCBI |
| FOXC2 | Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14) | UniProt NCBI |
| FOXC1 | Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3) | UniProt NCBI |
| ZNF235 | Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6) | UniProt NCBI |
| PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) | UniProt NCBI |
| PTPDC1 | Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-) | UniProt NCBI |
| ZFP1 | Zinc finger protein 1 homolog (Zfp-1) (Zinc finger protein 475) | UniProt NCBI |
| FAM122A | Protein FAM122A | UniProt NCBI |
| FAM214A | Protein FAM214A | UniProt NCBI |
| CDCA4 | Cell division cycle-associated protein 4 (Hematopoietic progenitor protein) | UniProt NCBI |
| PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) | UniProt NCBI |
| FAM122B | Protein FAM122B | UniProt NCBI |
| XPOT | Exportin-T (Exportin(tRNA)) (tRNA exportin) | UniProt NCBI |
| SERTAD4 | SERTA domain-containing protein 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3927 | 0.00882682840019 | 0.133333333333 | FOXC2 FOXC1 | BMP Signaling Pathway in Eyelid Development |
| WP:WP1591 | 0.0404394629458 | 0.133333333333 | FOXC2 FOXC1 | Heart Development |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP2R2A | PPP2R2D | 1.0 | 0.949 | hein_WMM bioplex (PPP2R2D) bioplex_WMM boldt hein (PPP2R2D) gupta_WMM boldt_WMM |
| PPP2R2A | FAM122A | 0.935 | 0.85 | hein_WMM bioplex (FAM122A) bioplex_WMM hein (PPP2R2A) |
| PPP2R2D | FAM122A | 0.889 | 0.818 | hein_WMM bioplex (FAM122A,PPP2R2D) bioplex_WMM hein (PPP2R2D) |
| FOXC2 | PPP2R2D | 0.695 | 0.718 | hein_WMM bioplex (PPP2R2D) bioplex_WMM |
| SERTAD4 | PPP2R2D | 0.615 | 0.674 | bioplex (PPP2R2D,SERTAD4) bioplex_WMM |
| PPP2R2A | SERTAD4 | 0.254 | 0.478 | bioplex (SERTAD4) bioplex_WMM |
| PPP2R2D | FAM214A | 0.206 | 0.453 | bioplex (PPP2R2D) bioplex_WMM |
| PPP2R2D | FOXC1 | 0.072 | 0.355 | hein_WMM bioplex (PPP2R2D) bioplex_WMM |
| FAM122A | FAM122B | 0.055 | 0.311 | hein_WMM bioplex (FAM122A) bioplex_WMM |
| CDCA4 | PPP2R2D | 0.055 | 0.311 | hein_WMM bioplex (CDCA4,PPP2R2D) bioplex_WMM |
| SERTAD4 | ZNF235 | 0.052 | 0.3 | bioplex (SERTAD4) bioplex_WMM |
| UNG | PPP2R2D | 0.05 | 0.298 | hein_WMM hein (PPP2R2D) |
| PPP2R2D | FBXL16 | 0.047 | 0.293 | hein_WMM hein (PPP2R2D) |
| CDCA4 | PPP2R2A | 0.045 | 0.289 | hein_WMM bioplex (CDCA4) bioplex_WMM hein (PPP2R2A) |
| ZFP1 | SERTAD4 | 0.032 | 0.242 | bioplex (SERTAD4) bioplex_WMM |
| PPP2R2D | PTPDC1 | 0.028 | 0.232 | bioplex (PTPDC1) bioplex_WMM boldt (PTPDC1) boldt_WMM |
| PPP2R2A | XPOT | 0.025 | 0.211 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PPP2R2A | PTPDC1 | 0.014 | 0.143 | bioplex (PTPDC1) bioplex_WMM boldt (PTPDC1) boldt_WMM |
| CDCA4 | FAM122A | 0.012 | 0.146 | hein_WMM bioplex_WMM WMM_only |
| CDCA4 | FOXC2 | 0.011 | 0.146 | hein_WMM bioplex_WMM WMM_only |
| FOXC2 | FOXC1 | 0.011 | 0.144 | hein_WMM bioplex_WMM WMM_only |
| FOXC2 | FAM122A | 0.01 | 0.134 | hein_WMM bioplex_WMM WMM_only |
| CDCA4 | SERTAD4 | 0.01 | 0.121 | bioplex_WMM WMM_only |
| CDCA4 | FOXC1 | 0.01 | 0.103 | hein_WMM bioplex_WMM WMM_only |
| SERTAD4 | FAM122A | 0.009 | 0.113 | bioplex_WMM WMM_only |
| FAM122A | FBXL16 | 0.009 | 0.104 | hein_WMM WMM_only |
| FAM122A | FOXC1 | 0.009 | 0.105 | hein_WMM bioplex_WMM WMM_only |
| FOXC2 | FAM214A | 0.009 | 0.095 | bioplex_WMM WMM_only |
| FOXC2 | FBXL16 | 0.009 | 0.099 | hein_WMM WMM_only |
| FOXC1 | FBXL16 | 0.009 | 0.099 | hein_WMM WMM_only |
| CDCA4 | FAM214A | 0.008 | 0.087 | bioplex_WMM WMM_only |
| FAM122A | FAM214A | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SERTAD4 | FOXC2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SERTAD4 | FAM214A | 0.008 | 0.085 | bioplex_WMM WMM_only |
| CDCA4 | FBXL16 | 0.008 | 0.082 | hein_WMM WMM_only |
| UNG | FAM122B | 0.008 | 0.067 | hein_WMM youn_WMM WMM_only |
| ZFP1 | ZNF235 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CDCA4 | FAM122B | 0.008 | 0.035 | bioplex_WMM WMM_only |
| FOXC1 | FAM214A | 0.008 | 0.029 | bioplex_WMM WMM_only |
| UNG | FBXL16 | 0.008 | 0.023 | hein_WMM WMM_only |
| UNG | FAM122A | 0.008 | 0.023 | hein_WMM WMM_only |
| SERTAD4 | FAM122B | 0.007 | 0.012 | bioplex_WMM WMM_only |
| UNG | PPP2R2A | 0.007 | 0.006 | hein_WMM youn_WMM WMM_only |
| PPP2R2D | ZNF235 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| FAM122B | FBXL16 | 0.007 | 0.002 | hein_WMM WMM_only |
| PPP2R2A | ZNF235 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| PPP2R2A | FAM214A | 0.007 | 0.008 | bioplex_WMM WMM_only |
| SERTAD4 | FOXC1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| FOXC1 | XPOT | 0.007 | 0.001 | bioplex_WMM youn_WMM WMM_only |
| FAM122B | FOXC1 | 0.007 | 0.003 | youn_WMM WMM_only |
| PPP2R2D | XPOT | 0.007 | 0.003 | bioplex_WMM WMM_only |
| UNG | FOXC1 | 0.007 | 0.001 | youn_WMM WMM_only |
| FAM122B | XPOT | 0.007 | 0.003 | youn_WMM WMM_only |
| UNG | XPOT | 0.007 | 0.0 | youn_WMM WMM_only |
| ZFP1 | XPOT | 0.007 | 0.002 | youn_WMM WMM_only |
| ZFP1 | PPP2R2A | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| ZFP1 | PPP2R2D | 0.007 | 0.003 | bioplex_WMM WMM_only |
| PPP2R2A | FAM122B | 0.007 | 0.005 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PPP2R2A | FBXL16 | 0.005 | 0.008 | hein_WMM hein (PPP2R2A) |
| PPP2R2A | FOXC1 | 0.005 | 0.01 | hein_WMM bioplex_WMM youn_WMM hein (PPP2R2A) |
| PPP2R2D | FAM122B | 0.003 | 0.014 | hein_WMM bioplex_WMM hein (PPP2R2D) |
| PPP2R2A | FOXC2 | 0.0 | 0.008 | hein_WMM bioplex_WMM hein (PPP2R2A) |
Images
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Complex HuMAP2_03797 has an average edge precision of 0.163 which is ranked 6596 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UNG | HuMAP2_00728 HuMAP2_02007 HuMAP2_02476 HuMAP2_03797 |
| FBXL16 | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 HuMAP2_04602 |
| FOXC2 | HuMAP2_01142 HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| FOXC1 | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| ZNF235 | HuMAP2_02007 HuMAP2_03797 HuMAP2_05108 |
| PPP2R2D | HuMAP2_01142 HuMAP2_02007 HuMAP2_02812 HuMAP2_03564 HuMAP2_03797 |
| PTPDC1 | HuMAP2_02007 HuMAP2_03797 |
| ZFP1 | HuMAP2_00697 HuMAP2_02931 HuMAP2_03797 |
| FAM122A | HuMAP2_01142 HuMAP2_02007 HuMAP2_03564 HuMAP2_03797 HuMAP2_04512 HuMAP2_06203 |
| FAM214A | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| CDCA4 | HuMAP2_00115 HuMAP2_02007 HuMAP2_03797 HuMAP2_04512 |
| PPP2R2A | HuMAP2_01142 HuMAP2_02007 HuMAP2_03564 HuMAP2_03797 HuMAP2_04512 |
| FAM122B | HuMAP2_01385 HuMAP2_02190 HuMAP2_02560 HuMAP2_03569 HuMAP2_03797 HuMAP2_04534 |
| XPOT | HuMAP2_03797 HuMAP2_04290 |
| SERTAD4 | HuMAP2_01142 HuMAP2_02007 HuMAP2_03797 HuMAP2_05108 |