hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03808

Confidence: Medium

Genename	Protein Name	Links
CAND1	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)	UniProt NCBI
KPNA4	Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)	UniProt NCBI
KPNA3	Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-168276	0.00445214779833	0.666666666667	KPNA4 KPNA3	NS1 Mediated Effects on Host Pathways
REAC:R-HSA-168253	0.0046992786316	0.666666666667	KPNA4 KPNA3	Host Interactions with Influenza Factors
MIRNA:hsa-miR-154-3p	0.00634895043463	0.666666666667	CAND1 KPNA3	hsa-miR-154-3p
MIRNA:hsa-miR-487a-3p	0.0128404250361	0.666666666667	CAND1 KPNA3	hsa-miR-487a-3p
REAC:R-HSA-1169408	0.0147604473263	0.666666666667	KPNA4 KPNA3	ISG15 antiviral mechanism
REAC:R-HSA-1169410	0.0180259784934	0.666666666667	KPNA4 KPNA3	Antiviral mechanism by IFN-stimulated genes
MIRNA:hsa-miR-374a-3p	0.0243005432667	0.666666666667	CAND1 KPNA3	hsa-miR-374a-3p
MIRNA:hsa-miR-4700-3p	0.0257170229754	0.666666666667	KPNA4 CAND1	hsa-miR-4700-3p
MIRNA:hsa-miR-4477b	0.0317827062049	0.666666666667	KPNA4 CAND1	hsa-miR-4477b

Protein 1	Protein 2	Score	Precision	Evidence
KPNA4	KPNA3	1.0	0.949	hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM
KPNA3	CAND1	0.057	0.32	bioplex_WMM Guru gupta_WMM fraction treiber_WMM
KPNA4	CAND1	0.053	0.301	bioplex_WMM Guru gupta_WMM fraction

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ComplexPrecisionDistribution

Complex HuMAP2_03808 has an average edge precision of 0.523 which is ranked 2380 out of all 6965 complexes.

Related Complexes

Genename	Complexes
CAND1	HuMAP2_01882 HuMAP2_03808
KPNA4	HuMAP2_00216 HuMAP2_02831 HuMAP2_03808 HuMAP2_05463 HuMAP2_05713
KPNA3	HuMAP2_00216 HuMAP2_02831 HuMAP2_03808 HuMAP2_05463 HuMAP2_05713