hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03829
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STRADA | STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96) | UniProt NCBI |
| CHFR | E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR) | UniProt NCBI |
| DTX3 | Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING finger protein 154) (RING-type E3 ubiquitin transferase DTX3) | UniProt NCBI |
| CAB39L | Calcium-binding protein 39-like (Antigen MLAA-34) (MO25beta) (Mo25-like protein) | UniProt NCBI |
| C5orf24 | UPF0461 protein C5orf24 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-380972 | 0.00508433997358 | 0.4 | CAB39L STRADA | Energy dependent regulation of mTOR by LKB1-AMPK |
| REAC:R-HSA-165159 | 0.00995219083388 | 0.4 | CAB39L STRADA | mTOR signalling |
| KEGG:04152 | 0.0262966325762 | 0.4 | CAB39L STRADA | AMPK signaling pathway |
| KEGG:04150 | 0.0433693821301 | 0.4 | CAB39L STRADA | mTOR signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAB39L | STRADA | 0.893 | 0.819 | bioplex (CAB39L) bioplex_WMM |
| STRADA | C5orf24 | 0.128 | 0.398 | bioplex (C5orf24) bioplex_WMM |
| CHFR | C5orf24 | 0.079 | 0.351 | bioplex (C5orf24) bioplex_WMM |
| DTX3 | CHFR | 0.067 | 0.351 | bioplex (DTX3) bioplex_WMM |
| STRADA | CHFR | 0.008 | 0.04 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03829 has an average edge precision of 0.392 which is ranked 3409 out of all 6965 complexes.
Related Complexes