hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03835
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MIS18BP1 | Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243) | UniProt NCBI |
| MIS18A | Protein Mis18-alpha (FAPP1-associated protein 1) | UniProt NCBI |
| OIP5 | Protein Mis18-beta (Cancer/testis antigen 86) (CT86) (Opa-interacting protein 5) (OIP-5) | UniProt NCBI |
| CCDC170 | Coiled-coil domain-containing protein 170 | UniProt NCBI |
| CCDC96 | Coiled-coil domain-containing protein 96 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6434 | 1.35146690511e-09 | 0.6 | OIP5 MIS18A MIS18BP1 | MIS18 complex |
| REAC:R-HSA-606279 | 0.000161043167075 | 0.6 | OIP5 MIS18A MIS18BP1 | Deposition of new CENPA-containing nucleosomes at the centromere |
| REAC:R-HSA-774815 | 0.000161043167075 | 0.6 | OIP5 MIS18A MIS18BP1 | Nucleosome assembly |
| REAC:R-HSA-73886 | 0.000549269398166 | 0.6 | OIP5 MIS18A MIS18BP1 | Chromosome Maintenance |
| GO:0034080 | 0.0119783897598 | 0.6 | OIP5 MIS18A MIS18BP1 | CENP-A containing nucleosome assembly |
| GO:0061641 | 0.0119783897598 | 0.6 | OIP5 MIS18A MIS18BP1 | CENP-A containing chromatin organization |
| GO:0031055 | 0.0137266123698 | 0.6 | OIP5 MIS18A MIS18BP1 | chromatin remodeling at centromere |
| GO:0006336 | 0.022411068229 | 0.6 | OIP5 MIS18A MIS18BP1 | DNA replication-independent nucleosome assembly |
| GO:0034508 | 0.022411068229 | 0.6 | OIP5 MIS18A MIS18BP1 | centromere complex assembly |
| GO:0034724 | 0.0237016209836 | 0.6 | OIP5 MIS18A MIS18BP1 | DNA replication-independent nucleosome organization |
| GO:0043486 | 0.0264291737868 | 0.6 | OIP5 MIS18A MIS18BP1 | histone exchange |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MIS18A | OIP5 | 0.963 | 0.871 | bioplex (MIS18A,OIP5) bioplex_WMM youn_WMM gupta_WMM |
| CCDC96 | MIS18A | 0.877 | 0.811 | bioplex (MIS18A) bioplex_WMM |
| MIS18BP1 | MIS18A | 0.152 | 0.41 | bioplex (MIS18A) bioplex_WMM gupta_WMM |
| MIS18A | CCDC170 | 0.078 | 0.352 | bioplex (MIS18A) bioplex_WMM |
| CCDC96 | CCDC170 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CCDC170 | OIP5 | 0.008 | 0.065 | bioplex_WMM gupta_WMM WMM_only |
| CCDC96 | OIP5 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| MIS18BP1 | CCDC170 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| CCDC96 | MIS18BP1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| MIS18BP1 | OIP5 | 0.005 | 0.012 | bioplex (OIP5) bioplex_WMM gupta_WMM |
Images
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Complex HuMAP2_03835 has an average edge precision of 0.28 which is ranked 4882 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MIS18BP1 | HuMAP2_00565 HuMAP2_03835 |
| MIS18A | HuMAP2_00565 HuMAP2_01357 HuMAP2_02965 HuMAP2_03832 HuMAP2_03835 |
| OIP5 | HuMAP2_01357 HuMAP2_03832 HuMAP2_03835 HuMAP2_04792 |
| CCDC170 | HuMAP2_00565 HuMAP2_02965 HuMAP2_03832 HuMAP2_03835 |
| CCDC96 | HuMAP2_00565 HuMAP2_01357 HuMAP2_02965 HuMAP2_03832 HuMAP2_03835 |