hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03853
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) | UniProt NCBI |
| PSG4 | Pregnancy-specific beta-1-glycoprotein 4 (PS-beta-G-4) (PSBG-4) (Pregnancy-specific glycoprotein 4) (Pregnancy-specific beta-1-glycoprotein 9) (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) | UniProt NCBI |
| PSG11 | Pregnancy-specific beta-1-glycoprotein 11 (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific beta-1-glycoprotein 13) (PS-beta-G-13) (PSBG-13) (Pregnancy-specific glycoprotein 13) | UniProt NCBI |
| RNF157 | E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) | UniProt NCBI |
| PSG8 | Pregnancy-specific beta-1-glycoprotein 8 (PS-beta-G-8) (PSBG-8) (Pregnancy-specific glycoprotein 8) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-202733 | 0.000462229124052 | 0.6 | PSG4 PSG8 PSG11 | Cell surface interactions at the vascular wall |
| MIRNA:hsa-miR-4646-3p | 0.0450989032615 | 0.4 | PSG4 CELSR3 | hsa-miR-4646-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PSG4 | PSG11 | 0.534 | 0.638 | bioplex (PSG11) bioplex_WMM |
| PSG4 | PSG8 | 0.134 | 0.406 | bioplex (PSG8) bioplex_WMM |
| PSG8 | CELSR3 | 0.126 | 0.399 | bioplex (PSG8) bioplex_WMM |
| PSG8 | RNF157 | 0.073 | 0.355 | bioplex (PSG8) bioplex_WMM |
| PSG4 | CELSR3 | 0.009 | 0.1 | bioplex_WMM WMM_only |
| PSG4 | RNF157 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| CELSR3 | RNF157 | 0.008 | 0.044 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03853 has an average edge precision of 0.29 which is ranked 4743 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CELSR3 | HuMAP2_00026 HuMAP2_03853 HuMAP2_04334 |
| PSG4 | HuMAP2_00012 HuMAP2_00026 HuMAP2_03196 HuMAP2_03853 HuMAP2_06107 |
| PSG11 | HuMAP2_00012 HuMAP2_03196 HuMAP2_03853 |
| RNF157 | HuMAP2_00026 HuMAP2_03853 HuMAP2_04334 |
| PSG8 | HuMAP2_00026 HuMAP2_03009 HuMAP2_03853 HuMAP2_04334 HuMAP2_06107 |