hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03859
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MARVELD2 | MARVEL domain-containing protein 2 (Tricellulin) | UniProt NCBI |
| POMC | Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin] | UniProt NCBI |
| TTL | Tubulin--tyrosine ligase (TTL) (EC 6.3.2.25) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579031 | 0.0498572752401 | 0.333333333333 | POMC | Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| POMC | TTL | 0.165 | 0.42 | bioplex (POMC) bioplex_WMM |
| MARVELD2 | TTL | 0.057 | 0.323 | bioplex (MARVELD2) |
Images
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Complex HuMAP2_03859 has an average edge precision of 0.371 which is ranked 3622 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MARVELD2 | HuMAP2_03136 HuMAP2_03859 HuMAP2_03954 HuMAP2_05842 |
| POMC | HuMAP2_03859 HuMAP2_06802 |
| TTL | HuMAP2_03859 HuMAP2_06802 |