hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03862
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAD51D | DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) (TRAD) | UniProt NCBI |
| XRCC2 | DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:262 | 1.67592346237e-06 | 1.0 | XRCC2 RAD51D | RAD51L3-XRCC2 complex |
| CORUM:2228 | 5.02777038712e-06 | 1.0 | XRCC2 RAD51D | BLM-RAD51L3-XRCC2 complex |
| CORUM:258 | 1.00555407742e-05 | 1.0 | XRCC2 RAD51D | BCDX2 complex |
| CORUM:68 | 1.00555407742e-05 | 1.0 | XRCC2 RAD51D | BCDX2 complex |
| CORUM:251 | 1.00555407742e-05 | 1.0 | XRCC2 RAD51D | BCDX2 complex |
| CORUM:261 | 1.67592346237e-05 | 1.0 | XRCC2 RAD51D | RAD51B-RAD51C-RAD51D-XRCC2-XRCC3 complex |
| KEGG:03440 | 0.000113800084426 | 1.0 | XRCC2 RAD51D | Homologous recombination |
| REAC:R-HSA-5693554 | 0.000544675125272 | 1.0 | XRCC2 RAD51D | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) |
| REAC:R-HSA-5693568 | 0.000831258037338 | 1.0 | XRCC2 RAD51D | Resolution of D-loop Structures through Holliday Junction Intermediates |
| REAC:R-HSA-5693537 | 0.000884887588134 | 1.0 | XRCC2 RAD51D | Resolution of D-Loop Structures |
| REAC:R-HSA-5693616 | 0.00117817419405 | 1.0 | XRCC2 RAD51D | Presynaptic phase of homologous DNA pairing and strand exchange |
| REAC:R-HSA-5693579 | 0.00137425723915 | 1.0 | XRCC2 RAD51D | Homologous DNA Pairing and Strand Exchange |
| GO:0033063 | 0.00270494046827 | 1.0 | XRCC2 RAD51D | Rad51B-Rad51C-Rad51D-XRCC2 complex |
| REAC:R-HSA-5685942 | 0.00348592080174 | 1.0 | XRCC2 RAD51D | HDR through Homologous Recombination (HRR) |
| GO:0042148 | 0.00450823411379 | 1.0 | XRCC2 RAD51D | strand invasion |
| GO:0033061 | 0.00676235117068 | 1.0 | XRCC2 RAD51D | DNA recombinase mediator complex |
| REAC:R-HSA-5693567 | 0.014052618232 | 1.0 | XRCC2 RAD51D | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-5693538 | 0.0153849773846 | 1.0 | XRCC2 RAD51D | Homology Directed Repair |
| REAC:R-HSA-5693532 | 0.0224003929981 | 1.0 | XRCC2 RAD51D | DNA Double-Strand Break Repair |
| HP:0011835 | 0.0497341708567 | 0.5 | XRCC2 | Absent scaphoid |
| CORUM:5683 | 0.0499173803268 | 0.5 | XRCC2 | hRAD51C-hXRCC3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| XRCC2 | RAD51D | 0.758 | 0.747 | bioplex (XRCC2) bioplex_WMM |
Images
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Complex HuMAP2_03862 has an average edge precision of 0.747 which is ranked 1177 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAD51D | HuMAP2_02452 HuMAP2_03298 HuMAP2_03506 HuMAP2_03862 |
| XRCC2 | HuMAP2_00467 HuMAP2_02452 HuMAP2_03298 HuMAP2_03506 HuMAP2_03862 |