hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03863
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| USP22 | Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) | UniProt NCBI |
| ATXN7L1 | Ataxin-7-like protein 1 (Ataxin-7-like protein 4) | UniProt NCBI |
| USP27X | Ubiquitin carboxyl-terminal hydrolase 27 (EC 3.4.19.12) (Deubiquitinating enzyme 27) (Ubiquitin carboxyl-terminal hydrolase 22-like) (Ubiquitin thioesterase 27) (Ubiquitin-specific-processing protease 27) (X-linked ubiquitin carboxyl-terminal hydrolase 27) | UniProt NCBI |
| ENY2 | Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog) | UniProt NCBI |
| ATXN7 | Ataxin-7 (Spinocerebellar ataxia type 7 protein) | UniProt NCBI |
| ATXN7L3 | Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog) | UniProt NCBI |
| ATXN7L2 | Ataxin-7-like protein 2 | UniProt NCBI |
| PCDHB15 | Protocadherin beta-15 (PCDH-beta-15) | UniProt NCBI |
| TSFM | Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6643 | 6.10897359936e-09 | 0.5 | USP22 ATXN7L1 ATXN7L2 ATXN7L3 | SAGA complex, GCN5-linked |
| CORUM:6664 | 3.82814132258e-06 | 0.375 | ENY2 ATXN7L3 USP22 | STAGA complex, SPT3-linked |
| CORUM:6641 | 0.000326737313819 | 0.25 | USP22 ATXN7L3 | USP22-SAGA complex |
| GO:0000124 | 0.000837474301274 | 0.375 | ENY2 ATXN7L3 USP22 | SAGA complex |
| REAC:R-HSA-3214847 | 0.00813495132609 | 0.375 | ENY2 ATXN7L3 USP22 | HATs acetylate histones |
| GO:0016578 | 0.00896175085475 | 0.375 | ENY2 ATXN7L3 USP22 | histone deubiquitination |
| GO:0070461 | 0.0116327718591 | 0.375 | ENY2 ATXN7L3 USP22 | SAGA-type complex |
| GO:0071819 | 0.0126230555186 | 0.25 | ENY2 ATXN7L3 | DUBm complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATXN7L1 | ATXN7L3 | 1.0 | 0.949 | bioplex (ATXN7L3) bioplex_WMM |
| ATXN7L3 | ATXN7L2 | 0.987 | 0.901 | bioplex (ATXN7L3) bioplex_WMM |
| USP27X | ATXN7L3 | 0.981 | 0.896 | bioplex (ATXN7L3) bioplex_WMM |
| ATXN7L3 | USP22 | 0.938 | 0.85 | bioplex (ATXN7L3) bioplex_WMM |
| ATXN7 | ATXN7L3 | 0.696 | 0.718 | bioplex (ATXN7L3) bioplex_WMM |
| ATXN7L2 | TSFM | 0.69 | 0.715 | bioplex (TSFM) bioplex_WMM |
| ENY2 | ATXN7L3 | 0.347 | 0.536 | bioplex (ATXN7L3) bioplex_WMM |
| ENY2 | PCDHB15 | 0.026 | 0.22 | hein_WMM hein (PCDHB15) |
| ATXN7L1 | ATXN7 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| ATXN7L1 | ATXN7L2 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| ATXN7 | ATXN7L2 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| ATXN7L1 | USP27X | 0.009 | 0.108 | bioplex_WMM WMM_only |
| ENY2 | ATXN7L1 | 0.009 | 0.09 | bioplex_WMM WMM_only |
| USP27X | ATXN7L2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| USP27X | ATXN7 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| ENY2 | ATXN7L2 | 0.008 | 0.095 | bioplex_WMM WMM_only |
| ENY2 | ATXN7 | 0.008 | 0.095 | bioplex_WMM WMM_only |
| ENY2 | USP27X | 0.008 | 0.086 | bioplex_WMM WMM_only |
| ATXN7L1 | USP22 | 0.008 | 0.069 | bioplex_WMM WMM_only |
| ATXN7 | USP22 | 0.008 | 0.032 | bioplex_WMM WMM_only |
| USP22 | ATXN7L2 | 0.008 | 0.032 | bioplex_WMM WMM_only |
| USP27X | USP22 | 0.008 | 0.012 | bioplex_WMM WMM_only |
| ENY2 | USP22 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| USP27X | TSFM | 0.007 | 0.005 | bioplex_WMM WMM_only |
| USP22 | TSFM | 0.007 | 0.003 | youn_WMM gupta_WMM WMM_only |
| ENY2 | TSFM | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03863 has an average edge precision of 0.266 which is ranked 5105 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| USP22 | HuMAP2_03863 HuMAP2_04577 HuMAP2_04718 HuMAP2_04719 HuMAP2_05925 |
| ATXN7L1 | HuMAP2_02985 HuMAP2_03863 HuMAP2_03981 HuMAP2_04577 HuMAP2_04718 |
| USP27X | HuMAP2_02985 HuMAP2_03863 HuMAP2_03981 HuMAP2_04577 HuMAP2_04718 |
| ENY2 | HuMAP2_02985 HuMAP2_03863 HuMAP2_06547 |
| ATXN7 | HuMAP2_02985 HuMAP2_03863 HuMAP2_03981 HuMAP2_04718 |
| ATXN7L3 | HuMAP2_02985 HuMAP2_03863 HuMAP2_03981 HuMAP2_04577 HuMAP2_04718 |
| ATXN7L2 | HuMAP2_03863 HuMAP2_04577 HuMAP2_04629 |
| PCDHB15 | HuMAP2_03863 HuMAP2_06547 |
| TSFM | HuMAP2_03863 HuMAP2_04629 |