hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03873
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KMT2A | Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] | UniProt NCBI |
| KMT2B | Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 4) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7) | UniProt NCBI |
| CXXC1 | CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) | UniProt NCBI |
| SETD1A | Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.43) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) | UniProt NCBI |
| NCOA6 | Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein) | UniProt NCBI |
| RERE | Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein) | UniProt NCBI |
| KMT2D | Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.43) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) | UniProt NCBI |
| BOD1L1 | Biorientation of chromosomes in cell division protein 1-like 1 | UniProt NCBI |
| SETD1B | Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.43) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B) | UniProt NCBI |
| MDK | Midkine (MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein) | UniProt NCBI |
| ATN1 | Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) | UniProt NCBI |
| WDR5 | WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) | UniProt NCBI |
| ASH2L | Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) | UniProt NCBI |
| RBBP5 | Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3) | UniProt NCBI |
| KDM6A | Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) | UniProt NCBI |
| FAM199X | Protein FAM199X | UniProt NCBI |
| HCFC2 | Host cell factor 2 (HCF-2) (C2 factor) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042800 | 6.11799254372e-20 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | histone methyltransferase activity (H3-K4 specific) |
| CORUM:6470 | 2.07280763131e-17 | 0.411764705882 | ASH2L RBBP5 BOD1L1 HCFC2 SETD1B CXXC1 WDR5 | Set1B complex |
| GO:0035097 | 3.16484023508e-17 | 0.647058823529 | NCOA6 RBBP5 ASH2L KMT2A SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | histone methyltransferase complex |
| GO:0034708 | 9.26573292286e-16 | 0.647058823529 | NCOA6 RBBP5 ASH2L KMT2A SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | methyltransferase complex |
| GO:0051568 | 1.97054353454e-15 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | histone H3-K4 methylation |
| GO:0018024 | 2.560465454e-15 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | histone-lysine N-methyltransferase activity |
| CORUM:6467 | 2.97857249047e-15 | 0.352941176471 | WDR5 NCOA6 ASH2L KMT2D KDM6A RBBP5 | MLL4 complex |
| CORUM:6469 | 7.44171475608e-15 | 0.352941176471 | RBBP5 CXXC1 HCFC2 ASH2L WDR5 SETD1A | Set1A complex |
| CORUM:5195 | 7.44171475608e-15 | 0.352941176471 | RBBP5 ASH2L WDR5 KMT2B KDM6A NCOA6 | PTIP-HMT complex |
| GO:0042054 | 2.01754349441e-14 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | histone methyltransferase activity |
| CORUM:3075 | 3.27020765813e-14 | 0.352941176471 | WDR5 NCOA6 ASH2L KMT2D KDM6A RBBP5 | UTX-MLL2/3 complex |
| GO:0016279 | 4.41731640791e-14 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | protein-lysine N-methyltransferase activity |
| GO:0016278 | 5.31827842525e-14 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | lysine N-methyltransferase activity |
| CORUM:2730 | 2.6430054055e-13 | 0.294117647059 | SETD1B CXXC1 RBBP5 WDR5 ASH2L | Set1B complex |
| CORUM:2731 | 2.6430054055e-13 | 0.294117647059 | CXXC1 RBBP5 SETD1A WDR5 ASH2L | Set1A complex |
| GO:0034968 | 5.87110117159e-13 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | histone lysine methylation |
| REAC:R-HSA-3214841 | 1.21240082185e-12 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | PKMTs methylate histone lysines |
| GO:0008276 | 1.69073163303e-12 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | protein methyltransferase activity |
| GO:0018022 | 3.08859179405e-12 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | peptidyl-lysine methylation |
| GO:0008170 | 4.35194038244e-12 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | N-methyltransferase activity |
| GO:0016571 | 4.86493743113e-12 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | histone methylation |
| CORUM:6461 | 5.53913462445e-12 | 0.294117647059 | ASH2L RBBP5 KDM6A WDR5 NCOA6 | MLL3 complex |
| REAC:R-HSA-8936459 | 1.048766569e-11 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
| CORUM:6460 | 1.10708275342e-11 | 0.294117647059 | ASH2L RBBP5 KMT2D HCFC2 WDR5 | MLL2 complex |
| CORUM:1401 | 1.10708275342e-11 | 0.294117647059 | KMT2A RBBP5 SETD1A KMT2D WDR5 | MOF complex |
| GO:0048188 | 1.88156126781e-11 | 0.352941176471 | RBBP5 CXXC1 SETD1B ASH2L WDR5 SETD1A | Set1C/COMPASS complex |
| CORUM:1399 | 5.04882052328e-11 | 0.235294117647 | ASH2L RBBP5 KMT2D WDR5 | WDR5-ASH2L-RBBP5-MLL2 complex |
| CORUM:6457 | 5.04882052328e-11 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2A | MLL1 core complex |
| GO:0006479 | 8.18865632435e-11 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | protein methylation |
| GO:0008213 | 8.18865632435e-11 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | protein alkylation |
| CORUM:6851 | 2.52264707382e-10 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2A | MWRAD complex (MLL1, WDR5, RBBP5, ASH2L, DPY30) |
| GO:0008757 | 5.03757147827e-10 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | S-adenosylmethionine-dependent methyltransferase activity |
| REAC:R-HSA-3247509 | 1.11472748345e-09 | 0.529411764706 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KDM6A KMT2D RBBP5 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 1.11472748345e-09 | 0.529411764706 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KDM6A KMT2D RBBP5 | Chromatin organization |
| CORUM:1400 | 1.76338697506e-09 | 0.235294117647 | ASH2L RBBP5 KMT2D NCOA6 | ASCOM complex |
| CORUM:1256 | 1.76338697506e-09 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2A | MLL-HCF complex |
| CORUM:1254 | 1.76338697506e-09 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2B | Menin-associated histone methyltransferase complex |
| GO:0008168 | 1.81633548989e-09 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | methyltransferase activity |
| GO:0016741 | 2.83014669251e-09 | 0.529411764706 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KMT2D SETD1A | transferase activity, transferring one-carbon groups |
| CORUM:6462 | 3.52431045774e-09 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2A | MLL1 complex |
| REAC:R-HSA-8878171 | 1.2128142641e-08 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | Transcriptional regulation by RUNX1 |
| GO:0043414 | 1.79479468206e-08 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | macromolecule methylation |
| GO:0044666 | 2.33253150406e-08 | 0.294117647059 | ASH2L RBBP5 KDM6A KMT2D WDR5 | MLL3/4 complex |
| GO:0032259 | 3.52525715589e-08 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | methylation |
| GO:0045652 | 3.86595605783e-08 | 0.411764705882 | SETD1A ASH2L WDR5 KMT2A KMT2B KMT2D RBBP5 | regulation of megakaryocyte differentiation |
| GO:0030219 | 5.22207820314e-08 | 0.411764705882 | SETD1A ASH2L WDR5 KMT2A KMT2B KMT2D RBBP5 | megakaryocyte differentiation |
| CORUM:6850 | 5.37014188658e-08 | 0.176470588235 | ASH2L WDR5 RBBP5 | WRA complex (WDR5, RBBP5, ASH2L) |
| CORUM:6849 | 2.14654210848e-07 | 0.176470588235 | ASH2L WDR5 RBBP5 | WRAD complex (WDR5, RBBP5, ASH2L, DPY30) |
| CORUM:6845 | 2.14654210848e-07 | 0.176470588235 | ASH2L WDR5 RBBP5 | NIF1-ASH2L-RBBP5-WDR5 complex |
| CORUM:7367 | 2.14654210848e-07 | 0.176470588235 | ASH2L WDR5 RBBP5 | ASH2L-KDM6B-KDM6B-WDR5 complex |
| KEGG:00310 | 3.23053299605e-07 | 0.294117647059 | SETD1B KMT2A KMT2B KMT2D SETD1A | Lysine degradation |
| GO:0018205 | 3.32752526019e-07 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | peptidyl-lysine modification |
| CORUM:6340 | 5.36257130058e-07 | 0.176470588235 | ASH2L KMT2D RBBP5 | PITX2-MLL4-ASH2L-RBBP5-PTIP complex |
| REAC:R-HSA-5619507 | 6.23653571091e-07 | 0.352941176471 | WDR5 NCOA6 ASH2L KMT2D KDM6A RBBP5 | Activation of HOX genes during differentiation |
| REAC:R-HSA-5617472 | 6.23653571091e-07 | 0.352941176471 | WDR5 NCOA6 ASH2L KMT2D KDM6A RBBP5 | Activation of anterior HOX genes in hindbrain development during early embryogenesis |
| WP:WP2369 | 6.67919725034e-07 | 0.294117647059 | SETD1B KMT2A KMT2B KMT2D SETD1A | Histone Modifications |
| CORUM:5386 | 8.7193848414e-07 | 0.235294117647 | ASH2L RBBP5 WDR5 KMT2A | MLL1-WDR5 complex |
| GO:0016570 | 1.04743953552e-06 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | histone modification |
| GO:1990234 | 1.07690951522e-06 | 0.647058823529 | NCOA6 RBBP5 ASH2L KMT2A SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | transferase complex |
| GO:0016569 | 1.56833282804e-06 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | covalent chromatin modification |
| GO:0030099 | 3.30967373771e-06 | 0.470588235294 | NCOA6 RBBP5 ASH2L WDR5 KMT2A KMT2B KMT2D SETD1A | myeloid cell differentiation |
| GO:0006325 | 5.84090890574e-06 | 0.588235294118 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | chromatin organization |
| GO:0045637 | 9.38276295638e-06 | 0.411764705882 | SETD1A ASH2L WDR5 KMT2A KMT2B KMT2D RBBP5 | regulation of myeloid cell differentiation |
| GO:0044451 | 2.04449286854e-05 | 0.647058823529 | NCOA6 RBBP5 ASH2L KMT2A SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | nucleoplasm part |
| KEGG:04934 | 2.22418847978e-05 | 0.294117647059 | RBBP5 ASH2L KMT2A KMT2D WDR5 | Cushing syndrome |
| GO:1903706 | 2.43122026121e-05 | 0.470588235294 | MDK SETD1A ASH2L WDR5 KMT2A KMT2B KMT2D RBBP5 | regulation of hemopoiesis |
| GO:0030097 | 3.61958468547e-05 | 0.529411764706 | MDK NCOA6 RBBP5 ASH2L WDR5 KMT2A KMT2B KMT2D SETD1A | hemopoiesis |
| CORUM:2721 | 4.33591355368e-05 | 0.176470588235 | ASH2L WDR5 SETD1A | HCF-1 complex |
| GO:0048534 | 4.49350322324e-05 | 0.529411764706 | MDK NCOA6 RBBP5 ASH2L WDR5 KMT2A KMT2B KMT2D SETD1A | hematopoietic or lymphoid organ development |
| GO:0002520 | 7.79773550934e-05 | 0.529411764706 | MDK NCOA6 RBBP5 ASH2L WDR5 KMT2A KMT2B KMT2D SETD1A | immune system development |
| CORUM:1257 | 0.000172850469735 | 0.176470588235 | KMT2A WDR5 RBBP5 | ALL-1 supercomplex |
| CORUM:0000000 | 0.000193935089438 | 0.764705882353 | NCOA6 RBBP5 BOD1L1 ASH2L KMT2A SETD1B WDR5 HCFC2 CXXC1 KMT2B KDM6A KMT2D SETD1A | CORUM root |
| GO:1902494 | 0.000334175469582 | 0.647058823529 | NCOA6 RBBP5 ASH2L KMT2A SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | catalytic complex |
| GO:0051276 | 0.000547279675979 | 0.588235294118 | KMT2A RBBP5 ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D SETD1A | chromosome organization |
| HP:0005218 | 0.0011147633445 | 0.117647058824 | KMT2D KDM6A | Anoperineal fistula |
| HP:0011231 | 0.0011147633445 | 0.117647058824 | KMT2D KDM6A | Prominent eyelashes |
| HP:0000437 | 0.00126478794364 | 0.176470588235 | KMT2A KMT2D KDM6A | Depressed nasal tip |
| REAC:R-HSA-212436 | 0.00210864900921 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | Generic Transcription Pathway |
| REAC:R-HSA-3769402 | 0.00319907449972 | 0.176470588235 | ASH2L KMT2D RBBP5 | Deactivation of the beta-catenin transactivating complex |
| HP:0010447 | 0.0033420443378 | 0.117647058824 | KMT2D KDM6A | Anal fistula |
| HP:0000436 | 0.00357228189391 | 0.294117647059 | KMT2A KDM6A RERE KMT2D KMT2B | Abnormality of the nasal tip |
| REAC:R-HSA-73857 | 0.00472297469544 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | RNA Polymerase II Transcription |
| GO:0018193 | 0.00634353566295 | 0.529411764706 | KMT2A ASH2L SETD1B WDR5 CXXC1 KMT2B KDM6A KMT2D RBBP5 | peptidyl-amino acid modification |
| HP:0005819 | 0.00718499892275 | 0.176470588235 | KMT2A KMT2D KDM6A | Short middle phalanx of finger |
| GO:0005654 | 0.00724296738893 | 0.823529411765 | ATN1 NCOA6 RBBP5 BOD1L1 ASH2L KMT2A SETD1B WDR5 HCFC2 CXXC1 KMT2B KDM6A KMT2D SETD1A | nucleoplasm |
| MIRNA:hsa-miR-6719-3p | 0.00874574403308 | 0.176470588235 | KMT2A SETD1B KDM6A | hsa-miR-6719-3p |
| REAC:R-HSA-74160 | 0.0105057393904 | 0.470588235294 | SETD1A ASH2L SETD1B WDR5 KMT2A KMT2B KMT2D RBBP5 | Gene expression (Transcription) |
| REAC:R-HSA-1266738 | 0.0110380493192 | 0.411764705882 | NCOA6 ASH2L WDR5 KMT2A KDM6A KMT2D RBBP5 | Developmental Biology |
| HP:0007655 | 0.0111251923193 | 0.117647058824 | KMT2D KDM6A | Eversion of lateral third of lower eyelids |
| HP:0009843 | 0.0116529482079 | 0.176470588235 | KMT2A KMT2D KDM6A | Aplasia/Hypoplasia of the middle phalanges of the hand |
| HP:0025634 | 0.0116623507578 | 0.235294117647 | KMT2A KDM6A KMT2D RERE | Abnormal ureter physiology |
| MIRNA:hsa-miR-3189-5p | 0.0133124048285 | 0.176470588235 | SETD1A KMT2D WDR5 | hsa-miR-3189-5p |
| HP:0009833 | 0.0134715055303 | 0.176470588235 | KMT2A KMT2D KDM6A | Abnormal middle phalanx morphology of the hand |
| MIRNA:hsa-miR-4758-3p | 0.014856453261 | 0.176470588235 | SETD1A KMT2D WDR5 | hsa-miR-4758-3p |
| MIRNA:hsa-miR-5699-5p | 0.016513862164 | 0.176470588235 | SETD1A KMT2D WDR5 | hsa-miR-5699-5p |
| HP:0010314 | 0.0166765837362 | 0.117647058824 | KMT2D KDM6A | Premature thelarche |
| HP:0004871 | 0.0166765837362 | 0.117647058824 | KMT2D KDM6A | Perineal fistula |
| HP:0001007 | 0.0236865667579 | 0.235294117647 | KMT2A KDM6A KMT2D RERE | Hirsutism |
| MIRNA:hsa-miR-4660 | 0.0254760328328 | 0.176470588235 | KMT2A KMT2D SETD1B | hsa-miR-4660 |
| MIRNA:hsa-miR-27a-3p | 0.0270709698239 | 0.294117647059 | SETD1B KMT2A RBBP5 KMT2D ATN1 | hsa-miR-27a-3p |
| HP:0000687 | 0.0333279763674 | 0.176470588235 | KMT2A KMT2D KDM6A | Widely spaced teeth |
| REAC:R-HSA-201722 | 0.0383745779458 | 0.176470588235 | ASH2L KMT2D RBBP5 | Formation of the beta-catenin:TCF transactivating complex |
| HP:0001212 | 0.0399432405396 | 0.117647058824 | KMT2D KDM6A | Prominent fingertip pads |
| HP:0011298 | 0.0399432405396 | 0.117647058824 | KMT2D KDM6A | Prominent digit pad |
| HP:0004736 | 0.0399432405396 | 0.117647058824 | KMT2D KDM6A | Crossed fused renal ectopia |
| MIRNA:hsa-miR-92a-2-5p | 0.0426979844229 | 0.235294117647 | SETD1B KMT2A KMT2D MDK | hsa-miR-92a-2-5p |
| HP:0012048 | 0.0498955311578 | 0.117647058824 | KMT2B ATN1 | Oromandibular dystonia |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KMT2B | WDR5 | 1.0 | 0.949 | bioplex (WDR5) bioplex_WMM youn_WMM |
| WDR5 | RERE | 1.0 | 0.949 | hein_WMM bioplex (WDR5) bioplex_WMM hein (WDR5) gupta_WMM |
| WDR5 | KDM6A | 1.0 | 0.949 | bioplex (WDR5) bioplex_WMM |
| WDR5 | KMT2D | 0.999 | 0.946 | hein_WMM bioplex (WDR5) bioplex_WMM hein (WDR5) gupta_WMM boldt_WMM |
| CXXC1 | SETD1B | 0.997 | 0.931 | hein_WMM bioplex (CXXC1) bioplex_WMM youn_WMM hein (CXXC1,SETD1B) |
| CXXC1 | SETD1A | 0.994 | 0.919 | hein_WMM bioplex (CXXC1) bioplex_WMM youn_WMM hein (CXXC1) fraction |
| SETD1B | WDR5 | 0.981 | 0.896 | hein_WMM bioplex (WDR5) bioplex_WMM hein (SETD1B) |
| CXXC1 | BOD1L1 | 0.98 | 0.896 | hein_WMM bioplex (CXXC1) bioplex_WMM youn_WMM hein (BOD1L1,CXXC1) |
| KMT2B | HCFC2 | 0.97 | 0.881 | bioplex (HCFC2) bioplex_WMM |
| CXXC1 | WDR5 | 0.964 | 0.872 | hein_WMM bioplex (CXXC1,WDR5) bioplex_WMM hein (CXXC1,WDR5) |
| ASH2L | WDR5 | 0.931 | 0.846 | hein_WMM bioplex (WDR5) bioplex_WMM youn_WMM |
| WDR5 | SETD1A | 0.878 | 0.812 | hein_WMM bioplex (WDR5) bioplex_WMM youn_WMM |
| RBBP5 | WDR5 | 0.866 | 0.801 | hein_WMM bioplex (WDR5) bioplex_WMM youn_WMM |
| WDR5 | ATN1 | 0.832 | 0.779 | bioplex (WDR5) bioplex_WMM |
| CXXC1 | ASH2L | 0.677 | 0.706 | hein_WMM bioplex (CXXC1) bioplex_WMM youn_WMM hein (CXXC1) fraction |
| WDR5 | BOD1L1 | 0.635 | 0.685 | hein_WMM bioplex (WDR5) bioplex_WMM youn_WMM |
| WDR5 | FAM199X | 0.634 | 0.684 | bioplex (WDR5) bioplex_WMM gupta_WMM boldt_WMM |
| CXXC1 | RBBP5 | 0.617 | 0.675 | hein_WMM bioplex (CXXC1) bioplex_WMM youn_WMM hein (CXXC1) |
| HCFC2 | KMT2A | 0.483 | 0.613 | hein_WMM bioplex (HCFC2) bioplex_WMM youn_WMM |
| WDR5 | KMT2A | 0.273 | 0.486 | hein_WMM bioplex (WDR5) bioplex_WMM youn_WMM gupta_WMM |
| SETD1A | BOD1L1 | 0.157 | 0.416 | hein_WMM bioplex_WMM youn_WMM hein (BOD1L1) |
| WDR5 | NCOA6 | 0.137 | 0.406 | bioplex (WDR5) bioplex_WMM youn_WMM |
| ASH2L | HCFC2 | 0.078 | 0.353 | hein_WMM bioplex (HCFC2) bioplex_WMM |
| HCFC2 | SETD1A | 0.06 | 0.336 | bioplex (HCFC2) bioplex_WMM youn_WMM |
| RBBP5 | SETD1B | 0.043 | 0.269 | hein_WMM bioplex_WMM youn_WMM hein (SETD1B) |
| RBBP5 | HCFC2 | 0.037 | 0.265 | bioplex (HCFC2) bioplex_WMM |
| RBBP5 | ASH2L | 0.034 | 0.26 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CXXC1 | HCFC2 | 0.026 | 0.219 | bioplex (CXXC1,HCFC2) bioplex_WMM |
| SETD1A | MDK | 0.022 | 0.199 | bioplex (MDK) bioplex_WMM |
| ASH2L | SETD1B | 0.016 | 0.155 | hein_WMM bioplex_WMM youn_WMM hein (SETD1B) |
| HCFC2 | WDR5 | 0.014 | 0.144 | hein_WMM bioplex (HCFC2,WDR5) bioplex_WMM |
| CXXC1 | MDK | 0.013 | 0.141 | bioplex (MDK) bioplex_WMM |
| HCFC2 | BOD1L1 | 0.013 | 0.147 | bioplex (HCFC2) bioplex_WMM youn_WMM |
| ASH2L | BOD1L1 | 0.012 | 0.147 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RBBP5 | SETD1A | 0.011 | 0.142 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| KMT2B | KMT2A | 0.011 | 0.145 | bioplex_WMM youn_WMM WMM_only |
| KMT2B | BOD1L1 | 0.01 | 0.142 | bioplex_WMM youn_WMM WMM_only |
| KMT2D | RERE | 0.01 | 0.133 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| SETD1B | SETD1A | 0.01 | 0.129 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCOA6 | KDM6A | 0.01 | 0.129 | bioplex_WMM youn_WMM WMM_only |
| KMT2D | NCOA6 | 0.01 | 0.13 | bioplex_WMM youn_WMM WMM_only |
| KMT2D | KDM6A | 0.01 | 0.121 | bioplex_WMM youn_WMM WMM_only |
| KMT2A | BOD1L1 | 0.01 | 0.121 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | BOD1L1 | 0.01 | 0.105 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| KMT2B | SETD1A | 0.01 | 0.101 | bioplex_WMM youn_WMM WMM_only |
| KMT2B | NCOA6 | 0.01 | 0.101 | bioplex_WMM youn_WMM WMM_only |
| KMT2D | ATN1 | 0.01 | 0.1 | bioplex_WMM youn_WMM WMM_only |
| ATN1 | KDM6A | 0.01 | 0.099 | bioplex_WMM youn_WMM WMM_only |
| NCOA6 | ATN1 | 0.01 | 0.099 | bioplex_WMM youn_WMM WMM_only |
| KMT2A | NCOA6 | 0.01 | 0.103 | bioplex_WMM youn_WMM WMM_only |
| BOD1L1 | NCOA6 | 0.009 | 0.112 | bioplex_WMM youn_WMM WMM_only |
| KMT2B | KDM6A | 0.009 | 0.114 | bioplex_WMM youn_WMM WMM_only |
| SETD1A | KMT2A | 0.009 | 0.115 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| KMT2B | KMT2D | 0.009 | 0.109 | bioplex_WMM youn_WMM WMM_only |
| RERE | KDM6A | 0.009 | 0.104 | bioplex_WMM WMM_only |
| NCOA6 | RERE | 0.009 | 0.103 | bioplex_WMM WMM_only |
| ATN1 | RERE | 0.009 | 0.103 | bioplex_WMM WMM_only |
| KMT2B | ATN1 | 0.009 | 0.108 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | ATN1 | 0.009 | 0.107 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | NCOA6 | 0.009 | 0.107 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | KMT2D | 0.009 | 0.104 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | KDM6A | 0.009 | 0.104 | bioplex_WMM youn_WMM WMM_only |
| ASH2L | KMT2B | 0.009 | 0.107 | bioplex_WMM youn_WMM WMM_only |
| RBBP5 | KMT2B | 0.009 | 0.108 | bioplex_WMM youn_WMM WMM_only |
| SETD1A | NCOA6 | 0.009 | 0.106 | bioplex_WMM youn_WMM WMM_only |
| BOD1L1 | KDM6A | 0.009 | 0.103 | bioplex_WMM youn_WMM WMM_only |
| KMT2A | KMT2D | 0.009 | 0.101 | bioplex_WMM youn_WMM WMM_only |
| KMT2A | KDM6A | 0.009 | 0.102 | bioplex_WMM youn_WMM WMM_only |
| CXXC1 | KMT2B | 0.009 | 0.1 | bioplex_WMM youn_WMM WMM_only |
| ASH2L | KMT2A | 0.009 | 0.103 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| KMT2B | RERE | 0.009 | 0.093 | bioplex_WMM WMM_only |
| RBBP5 | NCOA6 | 0.009 | 0.09 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SETD1B | KMT2B | 0.009 | 0.091 | bioplex_WMM youn_WMM WMM_only |
| BOD1L1 | ATN1 | 0.009 | 0.094 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | RERE | 0.009 | 0.094 | bioplex_WMM WMM_only |
| KMT2A | ATN1 | 0.009 | 0.095 | bioplex_WMM youn_WMM WMM_only |
| ASH2L | NCOA6 | 0.009 | 0.098 | bioplex_WMM youn_WMM WMM_only |
| CXXC1 | KMT2D | 0.009 | 0.097 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RBBP5 | KMT2D | 0.009 | 0.092 | bioplex_WMM youn_WMM WMM_only |
| SETD1A | KDM6A | 0.008 | 0.095 | bioplex_WMM youn_WMM WMM_only |
| ASH2L | KDM6A | 0.008 | 0.095 | bioplex_WMM youn_WMM WMM_only |
| ASH2L | KMT2D | 0.008 | 0.091 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RBBP5 | KDM6A | 0.008 | 0.087 | bioplex_WMM youn_WMM WMM_only |
| SETD1A | KMT2D | 0.008 | 0.089 | bioplex_WMM youn_WMM WMM_only |
| RBBP5 | KMT2A | 0.008 | 0.087 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| KMT2A | RERE | 0.008 | 0.088 | bioplex_WMM WMM_only |
| FAM199X | KDM6A | 0.008 | 0.088 | bioplex_WMM WMM_only |
| SETD1A | ATN1 | 0.008 | 0.089 | bioplex_WMM youn_WMM WMM_only |
| FAM199X | ATN1 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| FAM199X | KMT2D | 0.008 | 0.089 | bioplex_WMM WMM_only |
| FAM199X | NCOA6 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| CXXC1 | KDM6A | 0.008 | 0.088 | bioplex_WMM youn_WMM WMM_only |
| BOD1L1 | RERE | 0.008 | 0.09 | bioplex_WMM WMM_only |
| CXXC1 | ATN1 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| CXXC1 | NCOA6 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| CXXC1 | RERE | 0.008 | 0.084 | hein_WMM bioplex_WMM WMM_only |
| ASH2L | ATN1 | 0.008 | 0.082 | bioplex_WMM youn_WMM WMM_only |
| RBBP5 | ATN1 | 0.008 | 0.082 | bioplex_WMM youn_WMM WMM_only |
| SETD1B | KMT2A | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| FAM199X | RERE | 0.008 | 0.082 | bioplex_WMM WMM_only |
| SETD1A | RERE | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CXXC1 | KMT2A | 0.008 | 0.07 | bioplex_WMM youn_WMM WMM_only |
| KMT2B | FAM199X | 0.008 | 0.061 | bioplex_WMM WMM_only |
| ASH2L | RERE | 0.008 | 0.06 | bioplex_WMM WMM_only |
| SETD1B | HCFC2 | 0.008 | 0.059 | bioplex_WMM WMM_only |
| RBBP5 | RERE | 0.008 | 0.058 | bioplex_WMM WMM_only |
| HCFC2 | KDM6A | 0.008 | 0.051 | bioplex_WMM WMM_only |
| HCFC2 | NCOA6 | 0.008 | 0.048 | bioplex_WMM WMM_only |
| HCFC2 | ATN1 | 0.008 | 0.048 | bioplex_WMM WMM_only |
| HCFC2 | KMT2D | 0.008 | 0.048 | bioplex_WMM WMM_only |
| SETD1B | FAM199X | 0.008 | 0.042 | bioplex_WMM WMM_only |
| ASH2L | MDK | 0.008 | 0.031 | bioplex (MDK) bioplex_WMM |
| HCFC2 | RERE | 0.008 | 0.028 | bioplex_WMM WMM_only |
| RBBP5 | FAM199X | 0.008 | 0.011 | bioplex_WMM WMM_only |
| KMT2A | FAM199X | 0.008 | 0.008 | bioplex_WMM WMM_only |
| BOD1L1 | FAM199X | 0.008 | 0.011 | bioplex_WMM WMM_only |
| RBBP5 | MDK | 0.007 | 0.009 | bioplex (MDK) bioplex_WMM |
| ASH2L | FAM199X | 0.007 | 0.008 | bioplex_WMM WMM_only |
| SETD1A | FAM199X | 0.007 | 0.009 | bioplex_WMM WMM_only |
| BOD1L1 | MDK | 0.007 | 0.003 | bioplex (MDK) bioplex_WMM |
| CXXC1 | FAM199X | 0.007 | 0.006 | bioplex_WMM WMM_only |
| HCFC2 | FAM199X | 0.007 | 0.004 | bioplex_WMM WMM_only |
| WDR5 | MDK | 0.007 | 0.004 | bioplex (MDK) bioplex_WMM treiber_WMM |
| RBBP5 | BOD1L1 | 0.005 | 0.007 | hein_WMM bioplex_WMM youn_WMM hein (BOD1L1) |
| BOD1L1 | KMT2D | 0.004 | 0.014 | bioplex_WMM youn_WMM fraction |
| ASH2L | SETD1A | 0.0 | 0.014 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
Images
Click to enlarge
Complex HuMAP2_03873 has an average edge precision of 0.216 which is ranked 5932 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KMT2A | HuMAP2_02172 HuMAP2_03873 HuMAP2_04830 |
| KMT2B | HuMAP2_00640 HuMAP2_02172 HuMAP2_03451 HuMAP2_03873 |
| CXXC1 | HuMAP2_00581 HuMAP2_02172 HuMAP2_03130 HuMAP2_03873 HuMAP2_06127 HuMAP2_06953 |
| SETD1A | HuMAP2_02172 HuMAP2_03130 HuMAP2_03873 HuMAP2_06127 HuMAP2_06953 |
| NCOA6 | HuMAP2_03873 |
| RERE | HuMAP2_03873 |
| KMT2D | HuMAP2_03873 |
| BOD1L1 | HuMAP2_02172 HuMAP2_03130 HuMAP2_03873 HuMAP2_06127 HuMAP2_06218 HuMAP2_06953 |
| SETD1B | HuMAP2_00581 HuMAP2_02172 HuMAP2_03130 HuMAP2_03873 HuMAP2_06127 HuMAP2_06953 |
| MDK | HuMAP2_03873 HuMAP2_06953 |
| ATN1 | HuMAP2_03873 |
| WDR5 | HuMAP2_02172 HuMAP2_03873 HuMAP2_06127 |
| ASH2L | HuMAP2_00581 HuMAP2_02172 HuMAP2_03873 HuMAP2_06127 HuMAP2_06953 |
| RBBP5 | HuMAP2_00581 HuMAP2_02172 HuMAP2_03873 HuMAP2_06127 HuMAP2_06953 |
| KDM6A | HuMAP2_03873 |
| FAM199X | HuMAP2_03065 HuMAP2_03873 |
| HCFC2 | HuMAP2_00640 HuMAP2_02172 HuMAP2_03873 HuMAP2_06953 |