hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03888
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SPEN | Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) | UniProt NCBI |
| BCLAF1 | Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1) | UniProt NCBI |
| THRAP3 | Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2916 | 0.000115031710136 | 0.666666666667 | BCLAF1 THRAP3 | Interactome of polycomb repressive complex 2 (PRC2) |
| MIRNA:hsa-miR-877-3p | 0.0204817271963 | 1.0 | BCLAF1 THRAP3 SPEN | hsa-miR-877-3p |
| CORUM:2908 | 0.0499776345577 | 0.333333333333 | SPEN | RBP-Jkappa-SHARP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BCLAF1 | THRAP3 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (BCLAF1) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| BCLAF1 | SPEN | 0.094 | 0.356 | hein_WMM bioplex_WMM youn_WMM hein (BCLAF1) gupta_WMM |
| SPEN | THRAP3 | 0.008 | 0.086 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_03888 has an average edge precision of 0.464 which is ranked 2779 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SPEN | HuMAP2_02061 HuMAP2_03888 HuMAP2_06370 |
| BCLAF1 | HuMAP2_02061 HuMAP2_02065 HuMAP2_03888 HuMAP2_06370 |
| THRAP3 | HuMAP2_02065 HuMAP2_03888 |