hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03893
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FAM160A2 | FTS and Hook-interacting protein (FHIP) (Protein FAM160A2) | UniProt NCBI |
| AKTIP | AKT-interacting protein (Ft1) (Fused toes protein homolog) | UniProt NCBI |
| HOOK2 | Protein Hook homolog 2 (h-hook2) (hHK2) | UniProt NCBI |
| FAM160A1 | Protein FAM160A1 | UniProt NCBI |
| HOOK3 | Protein Hook homolog 3 (h-hook3) (hHK3) | UniProt NCBI |
| HOOK1 | Protein Hook homolog 1 (h-hook1) (hHK1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6109 | 6.09820937128e-17 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | FHF complex |
| GO:0070695 | 4.91515675326e-14 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | FHF complex |
| GO:0045022 | 2.13866479475e-08 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | early endosome to late endosome transport |
| GO:0098927 | 2.82455062118e-08 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | vesicle-mediated transport between endosomal compartments |
| GO:0008333 | 4.17250787048e-08 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | endosome to lysosome transport |
| GO:0007040 | 5.99169276346e-08 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | lysosome organization |
| GO:0080171 | 5.99169276346e-08 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | lytic vacuole organization |
| GO:0030897 | 1.80981361376e-07 | 0.666666666667 | HOOK1 AKTIP HOOK3 HOOK2 | HOPS complex |
| GO:0007032 | 5.92717909488e-07 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | endosome organization |
| GO:0007041 | 1.91660450295e-06 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | lysosomal transport |
| GO:0007034 | 6.55437615032e-06 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | vacuolar transport |
| GO:0007033 | 1.45244802245e-05 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | vacuole organization |
| GO:0016482 | 2.26451406257e-05 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | cytosolic transport |
| GO:0099023 | 0.000133653758006 | 0.666666666667 | HOOK1 AKTIP HOOK3 HOOK2 | vesicle tethering complex |
| GO:0016050 | 0.000537394564545 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | vesicle organization |
| GO:0010256 | 0.00159745773058 | 0.833333333333 | HOOK1 AKTIP FAM160A2 HOOK3 HOOK2 | endomembrane system organization |
| GO:0051959 | 0.00592798461195 | 0.5 | HOOK1 HOOK2 HOOK3 | dynein light intermediate chain binding |
| GO:0031122 | 0.0239073169747 | 0.5 | HOOK1 HOOK2 HOOK3 | cytoplasmic microtubule organization |
| CORUM:6116 | 0.0499726005494 | 0.166666666667 | HOOK1 | Hook1-Vps16 complex |
| CORUM:6117 | 0.0499726005494 | 0.166666666667 | HOOK1 | Hook1-Vps18 complex |
| CORUM:6118 | 0.0499726005494 | 0.166666666667 | HOOK1 | Hook1-Vps39 complex |
| CORUM:6119 | 0.0499726005494 | 0.166666666667 | HOOK1 | Hook1-Vps41 complex |
| CORUM:6120 | 0.0499726005494 | 0.166666666667 | HOOK2 | Hook2-Vps16 complex |
| CORUM:6121 | 0.0499726005494 | 0.166666666667 | HOOK2 | Hook2-Vps41 complex |
| CORUM:6122 | 0.0499726005494 | 0.166666666667 | HOOK3 | Hook3-Vps16 complex |
| CORUM:6123 | 0.0499726005494 | 0.166666666667 | HOOK3 | Hook3-Vps41 complex |
| CORUM:6124 | 0.0499726005494 | 0.166666666667 | AKTIP | FTS-Vps16 complex |
| CORUM:6125 | 0.0499726005494 | 0.166666666667 | AKTIP | FTS-Vps18 complex |
| CORUM:6126 | 0.0499726005494 | 0.166666666667 | AKTIP | FTS-Vps41 complex |
| CORUM:7441 | 0.0499726005494 | 0.166666666667 | HOOK1 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AKTIP | FAM160A2 | 1.0 | 0.949 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| AKTIP | FAM160A1 | 1.0 | 0.949 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| AKTIP | HOOK3 | 0.999 | 0.949 | bioplex (AKTIP,HOOK3) bioplex_WMM youn_WMM gupta_WMM |
| AKTIP | HOOK1 | 0.989 | 0.904 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| HOOK3 | FAM160A2 | 0.887 | 0.818 | bioplex (HOOK3) bioplex_WMM youn_WMM |
| AKTIP | HOOK2 | 0.786 | 0.758 | bioplex (AKTIP) bioplex_WMM |
| HOOK3 | FAM160A1 | 0.241 | 0.468 | bioplex (HOOK3) bioplex_WMM youn_WMM |
| HOOK1 | HOOK3 | 0.025 | 0.215 | bioplex (HOOK3) bioplex_WMM youn_WMM gupta_WMM fraction |
| FAM160A1 | FAM160A2 | 0.012 | 0.149 | bioplex_WMM youn_WMM WMM_only |
| HOOK1 | FAM160A2 | 0.011 | 0.145 | bioplex_WMM youn_WMM WMM_only |
| HOOK1 | FAM160A1 | 0.01 | 0.112 | bioplex_WMM youn_WMM WMM_only |
| FAM160A2 | HOOK2 | 0.01 | 0.1 | bioplex_WMM WMM_only |
| FAM160A1 | HOOK2 | 0.008 | 0.077 | bioplex_WMM WMM_only |
| HOOK3 | HOOK2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| HOOK1 | HOOK2 | 0.008 | 0.011 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03893 has an average edge precision of 0.444 which is ranked 2913 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FAM160A2 | HuMAP2_00058 HuMAP2_03893 HuMAP2_05370 |
| AKTIP | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |
| HOOK2 | HuMAP2_03373 HuMAP2_03773 HuMAP2_03893 HuMAP2_04886 HuMAP2_05370 |
| FAM160A1 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |
| HOOK3 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |
| HOOK1 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 HuMAP2_06146 |