hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03894
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRAK2 | Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein) | UniProt NCBI |
| TRAK1 | Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) | UniProt NCBI |
| CARD19 | Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD) | UniProt NCBI |
| RHOT1 | Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:177 | 1.50819606993e-05 | 0.5 | TRAK1 TRAK2 | OGT-TRAK1-TRAK2 complex |
| GO:0034643 | 0.000165189908538 | 0.75 | TRAK1 TRAK2 RHOT1 | establishment of mitochondrion localization, microtubule-mediated |
| GO:0047497 | 0.000165189908538 | 0.75 | TRAK1 TRAK2 RHOT1 | mitochondrion transport along microtubule |
| GO:0051654 | 0.000246852342475 | 0.75 | TRAK1 TRAK2 RHOT1 | establishment of mitochondrion localization |
| GO:0051646 | 0.00147288799354 | 0.75 | TRAK1 TRAK2 RHOT1 | mitochondrion localization |
| GO:0098957 | 0.00270494046827 | 0.5 | TRAK1 TRAK2 | anterograde axonal transport of mitochondrion |
| GO:0072384 | 0.0150889595431 | 0.75 | TRAK1 TRAK2 RHOT1 | organelle transport along microtubule |
| CORUM:5832 | 0.0499140284799 | 0.25 | TRAK1 | PINK1-MIRO2-Milton complex |
| CORUM:5836 | 0.0499140284799 | 0.25 | TRAK1 | MIRO2-Milton complex |
| CORUM:7345 | 0.0499140284799 | 0.25 | TRAK1 | DISC1-TRAK1 complex |
| CORUM:7346 | 0.0499140284799 | 0.25 | RHOT1 | DISC1-RHOT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TRAK2 | TRAK1 | 0.991 | 0.909 | bioplex (TRAK2) bioplex_WMM |
| CARD19 | TRAK2 | 0.801 | 0.766 | bioplex (TRAK2) bioplex_WMM |
| TRAK2 | RHOT1 | 0.198 | 0.45 | bioplex (TRAK2) bioplex_WMM |
| CARD19 | TRAK1 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| TRAK1 | RHOT1 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| CARD19 | RHOT1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03894 has an average edge precision of 0.375 which is ranked 3582 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRAK2 | HuMAP2_01016 HuMAP2_01718 HuMAP2_03894 HuMAP2_04384 |
| TRAK1 | HuMAP2_01016 HuMAP2_01718 HuMAP2_03894 HuMAP2_04384 |
| CARD19 | HuMAP2_00654 HuMAP2_01011 HuMAP2_01016 HuMAP2_01309 HuMAP2_02736 HuMAP2_03894 HuMAP2_04384 HuMAP2_04962 |
| RHOT1 | HuMAP2_01718 HuMAP2_03894 HuMAP2_04384 HuMAP2_05277 |