hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03896
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NFKB2 | Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit] | UniProt NCBI |
| REL | Proto-oncogene c-Rel | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2084 | 1.67592346237e-05 | 1.0 | NFKB2 REL | NFKB1-NFKB2-REL-RELA-RELB complex |
| CORUM:5194 | 6.03332446455e-05 | 1.0 | NFKB2 REL | TNF-alpha/NF-kappa B signaling complex (SEC16A, CHUK, IKBKB, NFKB2, REL, IKBKG, MAP3K14, RELA, FBXW7, USP2) |
| CORUM:5193 | 0.000110610948517 | 1.0 | NFKB2 REL | TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) |
| CORUM:5196 | 0.000110610948517 | 1.0 | NFKB2 REL | TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1) |
| CORUM:5230 | 0.000110610948517 | 1.0 | NFKB2 REL | CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex |
| WP:WP3858 | 0.000140835743389 | 1.0 | NFKB2 REL | Toll-like Receptor Signaling |
| WP:WP4329 | 0.000162072879297 | 1.0 | NFKB2 REL | miRNAs involvement in the immune response in sepsis |
| WP:WP3617 | 0.000162072879297 | 1.0 | NFKB2 REL | Photodynamic therapy-induced NF-kB survival signaling |
| CORUM:5232 | 0.000227925590883 | 1.0 | NFKB2 REL | TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I) |
| CORUM:5233 | 0.000462554875615 | 1.0 | NFKB2 REL | TNF-alpha/NF-kappa B signaling complex 5 |
| WP:WP231 | 0.00142624133782 | 1.0 | NFKB2 REL | TNF alpha Signaling Pathway |
| KEGG:05203 | 0.00256458703081 | 1.0 | NFKB2 REL | Viral carcinogenesis |
| WP:WP4217 | 0.00257192893285 | 1.0 | NFKB2 REL | Ebola Virus Pathway on Host |
| WP:WP3926 | 0.038834152205 | 0.5 | NFKB2 | ApoE and miR-146 in inflammation and atherosclerosis |
| WP:WP4562 | 0.0443803979089 | 0.5 | REL | Canonical NF-KB pathway |
| HP:0030804 | 0.0497341708567 | 0.5 | NFKB2 | Trachyonychia |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NFKB2 | REL | 0.755 | 0.747 | hein_WMM bioplex (REL) bioplex_WMM |
Images
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Complex HuMAP2_03896 has an average edge precision of 0.747 which is ranked 1177 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NFKB2 | HuMAP2_01917 HuMAP2_03076 HuMAP2_03896 |
| REL | HuMAP2_01917 HuMAP2_03076 HuMAP2_03896 |