hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03897
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HEATR5A | HEAT repeat-containing protein 5A | UniProt NCBI |
| PPM1A | Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) | UniProt NCBI |
| PPM1B | Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta) | UniProt NCBI |
| INPPL1 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2) | UniProt NCBI |
| ARFGAP1 | ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0006499 | 0.0270421395626 | 0.4 | PPM1A PPM1B | N-terminal protein myristoylation |
| GO:0018377 | 0.0270421395626 | 0.4 | PPM1A PPM1B | protein myristoylation |
| GO:0006498 | 0.0450641792523 | 0.4 | PPM1A PPM1B | N-terminal protein lipidation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPM1A | PPM1B | 0.999 | 0.949 | bioplex (PPM1A) bioplex_WMM boldt_WMM |
| HEATR5A | PPM1B | 0.553 | 0.645 | bioplex (PPM1B) bioplex_WMM |
| INPPL1 | PPM1A | 0.383 | 0.55 | bioplex (PPM1A) bioplex_WMM |
| INPPL1 | ARFGAP1 | 0.184 | 0.437 | bioplex (ARFGAP1) bioplex_WMM youn_WMM |
| HEATR5A | ARFGAP1 | 0.007 | 0.005 | youn_WMM WMM_only |
| HEATR5A | INPPL1 | 0.007 | 0.001 | youn_WMM WMM_only |
| INPPL1 | PPM1B | 0.006 | 0.007 | bioplex_WMM WMM_only |
| ARFGAP1 | PPM1B | 0.0 | 0.014 | bioplex_WMM fraction |
Images
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Complex HuMAP2_03897 has an average edge precision of 0.326 which is ranked 4263 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HEATR5A | HuMAP2_00986 HuMAP2_02243 HuMAP2_03317 HuMAP2_03897 |
| PPM1A | HuMAP2_03588 HuMAP2_03897 HuMAP2_05609 |
| PPM1B | HuMAP2_03897 HuMAP2_05609 |
| INPPL1 | HuMAP2_02612 HuMAP2_03588 HuMAP2_03897 |
| ARFGAP1 | HuMAP2_02612 HuMAP2_02622 HuMAP2_03588 HuMAP2_03897 |